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Found 645 iu-health-enterprise-system trials

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on the Effectiveness of Investigational Medication Versus Standard Treatment for Glioblastoma, a Type of Brain Cancer

K
Kathryn Nevel
18 years - 100 years
All genders
Phase 3
This study investigates the effectiveness and safety of an investigational medication compared to a standard treatment in adults with newly-diagnosed glioblastoma. Glioblastoma is a type of brain cancer. The study aims to see if the investigational medication can improve the time patients live without the cancer getting worse and overall …
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Investigating Safety and Effectiveness of an Investigational Medication for Low-grade Upper Tract Urothelial Cancer

H
Hristos Kaimakliotis, MD
18 years - 100 years
All genders
Phase 1/2
This study investigates the safety and effectiveness of an investigational medication for adults with low-grade upper tract urothelial carcinoma (LG-UTUC). LG-UTUC is a type of cancer that occurs in the urinary system, specifically the upper part of the ureter and kidney. The study will involve a safety lead-in period for …
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Investigation of an Investigational Medication for Advanced Solid Tumors with FGFR3 Alterations

T
Tareq Salous
18 years - 100 years
All genders
Phase 1
This study investigates the safety, side effects, and effectiveness of an investigational medication in treating advanced solid tumors with FGFR3 alterations, including metastatic urothelial cancer. FGFR3 is a gene that, when altered, can contribute to the growth of cancer cells. The purpose of this study is to understand how the …
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Study of Eye Health in Patients Using a Medication Being Studied for Cervical Cancer

S
Sharon E. Robertson
18 years - 100 years
Female
Phase 4
This study investigates the effects of an investigational medication on eye health in patients with recurrent or metastatic cervical cancer. Cervical cancer occurs when cells in the cervix grow uncontrollably. This study focuses on understanding any side effects related to the eyes that may arise from the treatment. A side …
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Voice Measures & Respiratory Kinematics in Children & Adults with & without Voice & Resonance Disorders

R
Robert Fujiki
4 years - 80 years
All genders
Observational
This study will examine laryngeal physiology and respiratory kinematics in children and adults with and without voice disorders and cleft palate.THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential participants for the patient group will be patients of the Voice and Swallow Clinics, or craniofacial anomalies clinic at IUH. Speech-Language …
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Study on Timing of Surveillance Colonoscopy After Growth (Polyp) Removal

J
John Guardiola
18 years - 100 years
All genders
Interventional
This study investigates the timing of follow-up colonoscopies after the removal of nonpedunculated colorectal polyps. These are growths in the colon that do not have a stalk and are between 20 to 50 mm in size. The purpose of this study is to see if having a follow-up colonoscopy at …
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Investigating Radiation Therapy for High-Risk Asymptomatic Bone Metastases (cancer that has spread to other parts of the body)

A
Arpan Prabhu
18 years - 100 years
All genders
Phase 3
This study investigates the effect of adding radiation therapy to usual care for patients with high-risk asymptomatic bone metastases. Bone metastases are cancer cells that have spread to the bones. High-risk means they are more likely to cause problems like fractures or pain. Radiation therapy uses powerful x-rays to kill …
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Research Study on the Safety and Effects of an Investigational Medication with Radiation in Children with High Grade Glioma

B
Brian Weiss
12 months - 22 years
All genders
Phase 1
This study investigates the safety and effects of an investigational medication when combined with radiation therapy in children with high grade glioma. High grade glioma is a type of cancer that occurs in the brain. The investigational medication works by blocking signals that make cancer cells grow, which may help …
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Research on Medicine for Pancreatic and Lung Cancer

A
Anita Turk, MD
18 years - 100 years
All genders
This study investigates the safety and effects of an investigational medication in combination with other agents for patients with pancreatic or non-small cell lung cancer. These cancers are being studied because they have specific genetic changes called MTAP loss and RAS mutation. The purpose is to see how the investigational …
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Investigating Additional Treatments for Infant Blood Cancer

A
Amanda J. Saraf, DO
1 year or below
All genders
Phase 2
This study investigates the addition of investigational medication and investigational immunotherapy to the usual chemotherapy for infants with newly diagnosed acute lymphoblastic leukemia (ALL). ALL is a type of cancer where the bone marrow makes too many immature lymphocytes (a type of white blood cell). In this study, the researchers …
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