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Found 645 iu-health-enterprise-system trials

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Prospective Randomized Controlled Trial of Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System

T
Thomas Nowak, MD
18 years - 100 years
All genders
Interventional
What is the purpose of this study?The purpose of this research study is to determine if the Enterra® Therapy System can decrease nausea and vomiting symptoms and improve the quality of life for patients with chronic nausea, with or without vomiting, that have normal gastric emptying. THIS STUDY IS ENROLLING BY …
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Sample Collection to Assess Physioxia in Brain Tumors

A
Angela M. Richardson, MD, PhD
18 years or above
All genders
What is the purpose of this study?The purpose of this study is to look at the effect of oxygen on tumor tissue and cerebrospinal fluid(CSF). Tissue in your body is exposed to less oxygen than is in the air around you. Traditional studies use cells and tissue kept in room …
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The Utility of Silk Bioprotein as a Wound Dressing in Female-to-Male Double-Incision Mastectomy

I
Ivan Hadad
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This study will investigate the utility of Silk bioprotein, an FDA-approved and readily available post-surgical dressing, as a wound dressing for patients undergoing double-incision mastectomy for female-to-male gender affirmation surgery.THIS STUDY IS ENROLLING BY INVITATION ONLY - Patients will be those who are already …
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A Phase II Study of Amivantamab SC (subcutaneous) in Participants with MET Amplification-Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study)

R
Rohan Maniar
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
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Personality traits and induced laryngeal obstruction

R
Robert Fujiki
8 years - 80 years
Accepts healthy volunteer
All genders
What is the purpose of this study?Paradoxical Vocal Fold Movement (PVFM; also called Induced Laryngeal Obstruction [ILO]) consists of vocal fold adduction which occurs upon inspiration and results in dyspnea. The etiology of PVFM is often multifactorial and varied across patients. PVFM has been categorized in the literature based on …
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Study on Investigational Therapy for Myasthenia Gravis

A
Alex Barboi
18 years - 75 years
All genders
Phase 2/3
Interventional
This study investigates the use of an investigational therapy for people with generalized myasthenia gravis (MG), a chronic disease that causes muscle weakness. MG affects the connection between nerves and muscles and involves the presence of certain antibodies. The investigational therapy uses special cells called T cells to target and …
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Investigating Lung Cell Populations in Pulmonary Vascular Disease

D
David Roe, MD
18 years - 60 years
Accepts healthy volunteer
All genders
This study investigates lung cell populations in patients with pulmonary vascular disease (PVD). Pulmonary vascular disease refers to conditions affecting the blood vessels in the lungs, which can lead to serious health issues. The purpose of this study is to understand the differences in lung cell populations between those with …
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Study on Low-Dose Radiation Therapy for Joint Pain Relief

A
Arpan Prabhu
40 years or above
All genders
Phase 2
Observational
This study investigates the use of low-dose radiation therapy (LDRT) for treating osteoarthritis, a condition that causes joint pain and stiffness. Osteoarthritis is a common form of arthritis where the protective cartilage that cushions the ends of bones wears down over time. The purpose of this study is to evaluate …
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Study on Adding an Investigational Medication to Chemotherapy for High-Risk Leukemia

S
Sandeep Batra, MD
1 year - 25 years
All genders
Phase 3
Interventional
This study investigates the effectiveness of adding an investigational medication to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL). It also examines outcomes for patients with mixed phenotype acute leukemia (MPAL) and B-lymphoblastic lymphoma (B-LLy) treated with standard chemotherapy. B-ALL is a type of cancer that affects …
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Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation (VCSIP-ECHO)

R
Robert Tepper, MD
6 months - 11 years
All genders
Observational
In a randomized clinical trial (RCT) published in JAMA, the investigators have providedvidence that vitamin C supplementation (500 mg daily during pregnancy) ameliorates theking during pregnancy on offspring lung function and subsequentdence of wheeze by 48% through 1 year of age. The investigators are currently completingd RCT of vitamin C …
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