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Found 607 iu-health-enterprise-system trials
A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Heba Ismail
What is the purpose of this study?The purpose of this study is to evaluate the gut microbiome and circulating microbial metabolites of children and adults with prediabetes and diabetes so we can compare the differences across different stages of diabetes but also across different forms of diabetes and different age …
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Stacey Tarvin, MD
This study investigates how childhood-onset neuropsychiatric systemic lupus erythematosus (NPSLE) affects cognitive functions over time. Systemic lupus erythematosus (SLE) is a disease where the immune system attacks the body, causing inflammation and damage. The study uses a tool called pedANAM to assess cognitive and behavioral functions in children with this …
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April Savoy
For patients and caregivers, ADRD-DM presents unique challenges for detecting and preventing hypoglycemia.Individualized care for people with ADRD-DM should be based on patient and caregiver goals along with patients’ cognitive and physical abilities, reported outcomes, and hypoglycemia risk, based largely on prior hypoglycemic events. Providing details of hypoglycemic events and risks …
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Sandeep Batra, MD
This study investigates treatment options for children and young adults with low-grade glioma (LGG), a type of brain tumor. The purpose of this study is to compare the effects of an investigational medication with standard chemotherapy treatments, carboplatin and vincristine, in patients who do not have a specific genetic mutation …
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Anthony Ross
This study investigates an investigational medication for treating Langerhans cell histiocytosis (LCH), a disease where the body makes too many immature Langerhans cells, a type of white blood cell. These cells can build up and form tumors in organs like bones, skin, and lungs, causing damage. The purpose of the …
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Jared Brosch, MD
What is the purpose of this study?To assess the safety, tolerability, biomarker, cognitive, and clinical efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with the study drug improves disease-related biomarkers and slows the rate of progression of cognitive or clinical impairment.THIS STUDY IS …
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Archita Desai, MD
This study investigates the use of the Cirrhosis Risk Instrument for Stratifying Post Emergency Department mortality (CRISPE) tool in individuals with cirrhosis. Cirrhosis is a condition where the liver becomes scarred and its function is impaired. The purpose of this study is to validate the CRISPE tool prospectively to predict …
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Rachael Schulte
This study investigates a treatment for PIK3CA Related Overgrowth Spectrum (PROS), a condition caused by a mutation in the PIK3CA gene that leads to abnormal growths in the body. The purpose of this study is to evaluate the safety and effectiveness of an investigational medication targeting these mutations.Participants in this …
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Shannon Hawkins
What is the purpose of this study?The purpose of this study is to collect female reproductive tract tissues to investigate the key molecular events regulating endometriosis. Our central hypothesis is that by using well-characterized tissues, we can create novel models to improve treatments for endometriosis. THIS STUDY IS ENROLLING BY INVITATION …
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Bryan Schneider, MD
What is the purpose of this study?This Phase III, randomized, open-label, multicenter study will evaluate the efficacy andy of giredestrant plus everolimus compared with the physician's choice of endocrineherapy plus everolimus in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer …
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