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Found 610 iu-health-enterprise-system trials

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

S
Shannon Hawkins
18 years or above
Female
What is the purpose of this study?The purpose of this study is to collect female reproductive tract tissues to investigate the key molecular events regulating endometriosis. Our central hypothesis is that by using well-characterized tissues, we can create novel models to improve treatments for endometriosis. THIS STUDY IS ENROLLING BY INVITATION …
B
Bryan Schneider, MD
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?This Phase III, randomized, open-label, multicenter study will evaluate the efficacy andy of giredestrant plus everolimus compared with the physician's choice of endocrineherapy plus everolimus in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer …
S
Sandeep Batra, MD
1 month - 21 years
All genders
Phase 3
Interventional
What is the purpose of this study?Rhabdomyosarcoma is a type of cancer that occurs in the soft tissues in the body. This phaseutcomes in patients with very low risk rhabdomyosarcoma (VLR-RMS) while decreasing the burden of therapy using treatment with 24 weeks of vincristined dactinomycin (VA) and examines the use …
S
Sandeep Batra, MD
21 years or below
All genders
Phase 3
Interventional
What is the purpose of this study?This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acuteyeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop …
T
Tony Navarrete
18 years - 100 years
All genders
Interventional
This study investigates two pacing methods for treating heart failure in patients with a specific heart condition. Heart failure is when the heart can't pump blood as well as it should. The study is comparing two types of cardiac-resynchronization therapy (CRT): biventricular pacing and pacing at the His or left …
K
Kathy Miller, MD
16 years - 100 years
All genders
Phase 3
This study investigates the effects of shorter chemotherapy-immunotherapy without anthracyclines compared to the usual treatment for early-stage triple negative breast cancer. Triple negative breast cancer is a type of breast cancer that does not have estrogen receptors, progesterone receptors, or too much of the protein called HER2. This study will …
T
Tim Lautenschlaeger, MD
18 years - 100 years
Accepts healthy volunteer
All genders
What is the purpose of this study?This study aims to invent a test that can see tiny pieces from people with cancer (specifically DNA from a person’s cancer) in blood and urine better than tests that can currently be done. In the future, this test can possibly be used to …
S
Sandeep Batra, MD
12 months - 21 years
All genders
Phase 1/2
Interventional
This study investigates the safety and effects of combining an investigational medication with radiation therapy in children and young adults who have been newly diagnosed with diffuse intrinsic pontine glioma (DIPG) or high-grade glioma (HGG), which are types of brain cancers. Glioma is a cancer that occurs in the brain …
K
Kathy Miller, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates the effects of an investigational medication alone compared to the same medication combined with tocilizumab in patients with advanced breast cancer. Advanced breast cancer includes conditions such as metastatic triple negative or ER-low breast cancer. This study involves Black and non-Black patients and aims to understand how …
N
Nawal Kassem
18 years - 100 years
All genders
This study investigates how to increase genetic testing in Black families with hereditary cancer syndromes. Hereditary cancer syndromes are conditions where gene changes increase the risk of cancer in families. The study focuses on Black patients who have been advised to undergo genetic testing. It aims to see if using …
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