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Found 649 iu-health-enterprise-system trials

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

M
Michael W. Sim, MD
18 years - 100 years
All genders
This study investigates a new approach for treating HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). The purpose of this study is to see if reducing the intensity of treatment, based on levels of ctHPVDNA (pieces of cancer DNA in blood samples), can be as effective as the standard treatment. OPSCC is …
T
Thomas Nowak, MD
18 years - 100 years
All genders
Interventional
What is the purpose of this study?The purpose of this research study is to determine if the Enterra® Therapy System can decrease nausea and vomiting symptoms and improve the quality of life for patients with chronic nausea, with or without vomiting, that have normal gastric emptying. THIS STUDY IS ENROLLING BY …
J
Jessica Parker Metter
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This phase III trial compares the effect of olaparib for one year versus two years, with or without bevacizumab, for the treatment of BRCA 1/2 mutated or homologous recombination deficient stage III or IV ovarian cancer. Olaparib is a polyadenosine 5'-diphosphoribose polymerase (PARP) enzyme …
A
Angela M. Richardson, MD, PhD
18 years or above
All genders
What is the purpose of this study?The purpose of this study is to look at the effect of oxygen on tumor tissue and cerebrospinal fluid(CSF). Tissue in your body is exposed to less oxygen than is in the air around you. Traditional studies use cells and tissue kept in room …
R
Robert Fujiki
8 years - 80 years
Accepts healthy volunteer
All genders
What is the purpose of this study?Paradoxical Vocal Fold Movement (PVFM; also called Induced Laryngeal Obstruction [ILO]) consists of vocal fold adduction which occurs upon inspiration and results in dyspnea. The etiology of PVFM is often multifactorial and varied across patients. PVFM has been categorized in the literature based on …
R
Rohan Maniar
18 years - 100 years
All genders
This study investigates the use of an investigational medication in treating people with early-stage non-small cell lung cancer (NSCLC) after surgery. NSCLC is a type of lung cancer that occurs when cells in the lung grow uncontrollably. The purpose of this study is to see if the investigational medication can …
A
Anita Turk, MD
18 years - 100 years
All genders
Phase 3
This study investigates treatments for metastatic colorectal cancer, which is a type of cancer that starts in the colon or rectum and spreads to other parts of the body. The purpose of this study is to compare two treatments: one using an investigational medication with a chemotherapy regimen called mFOLFOX6, …
T
Tarah Ballinger, MD
18 years - 100 years
All genders
Phase 3
This study investigates an investigational medication combined with other treatments for adults with advanced breast cancer that is hormone receptor-positive (HR+) and human epidermal growth factor receptor 2-negative (HER2-). Participants must have a specific gene change called a PIK3CA mutation and their cancer must have spread to other parts of …
M
Mike Davis
18 years or above
All genders
Observational
This study investigates a possible genetic disorder called Primary Ciliary Dyskinesia (PCD) in adults with bronchiectasis, a lung disease where the airways are damaged and infected repeatedly. PCD happens when tiny structures called cilia, which move mucus out of the lungs, do not work right. This can lead to mucus …
B
Brian Weiss
12 months - 21 years
All genders
Phase 1/2
Interventional
This study investigates the use of an investigational medication in patients with relapsed or refractory solid tumors, including central nervous system tumors and lymphoma. The purpose is to find the best dose and understand the side effects and potential benefits. Solid tumors and lymphoma are types of cancer that can …
581 - 590 of 649