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Found 711 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Utilizing Palliative Leaders In Facilities to Transform care for Alzheimer's Disease (UPLIFT-AD)

K
Kathleen Unroe, MD
18 years - 100 years
All genders
The purpose of this study is to evaluate a comprehensive model for integrating both primary and specialty Palliative Care into nursing facilities.
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Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

M
Mitesh Shah, MD
100 years or below
All genders
Observational
What is the purpose of this study?The objectives of this registry study are to evaluate real-world clinical outcomes andd outcomes that measure the effectiveness and safety of STaRT.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their …
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Analysis of urine sediment characteristics in nephritis using high resolution microscopy

A
Andrew Schwaderer, MD
7 years - 17 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to develop a test for kidney disease that does not require a kidney biopsy or blood draw.  We will look at urine samples under a microscope and see if we find patterns in the kind of cells and …
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Distal Radius Interventions for Fracture Treatment (DRIFT)

E
Erika Daley
4 years - 10 years
All genders
Interventional
This protocol describes a multicenter, prospective randomized superiority trial comparingunctional outcomes between children treated with sedated reduction versus no formalduction.
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Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen

K
Kate Hawa
2 years - 21 years
Accepts healthy volunteer
All genders
Phase 4
This study will evaluate changes in the fecal microbiome in constipated pediatric patients before and after antegrade continence enema placement and initiation of antegrade enemaushes. Subjects will have their microbiome sequenced prior to placement by obtaining a. Pre-antegrade continence enema placement results will be compared to fecalbtained at 0, 4, …
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A Randomized, Open-label, Multicentric, Two-arm Pivotal Trial of SonoCloud-9 Combined With Carboplatin (CBDCA) vs Standard of Care Lomustine (CCNU) or Temozolomide (TMZ) in Patients Undergoing Planned Resection for First Recurrence Glioblastoma.

K
Kathryn Nevel
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?The brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls. Because of these barrier properties, the blood vessels are also impermeable to the passage of therapeutic …
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Investigational Medicine to Stop Tumor Growth in Kids with NF1

S
Steven Rhodes
1 years - 8 years
All genders
Phase 2
This study investigates the use of an investigational medication to prevent the growth of plexiform neurofibromas in children with Neurofibromatosis Type 1 (NF1). NF1 is a genetic disorder that often causes tumors to grow on nerve tissues, which can lead to various health problems. The study aims to see if …
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A Phase 3, Open-label, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of Romosozumab Compared with Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta

E
Erik Imel, MD
5 years - 17 years
All genders
Phase 3
Interventional
What is the purpose of this study?The primary objective of this study is to evaluate the effect of romosozumab treatment for 12-months compared with bisphosphonate(s) on the number of clinical fractures at 12-months; the number of any fractures at 12-months and change in lumbar spine bone mineral density (BMD) Z-score …
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A Phase 2 Study Using Chemoimmunotherapy With Gemcitabine, Cisplatin and Nivolumab in Newly Diagnosed Nasopharyngeal Carcinoma (NPC)

M
Marissa Just
1 years - 21 years
All genders
Phase 2
This phase II trial tests how well nivolumab in combination with chemotherapy drugs along with radiation therapy works in treating patients with nasopharyngeal cancer. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to …
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AN OBSERVATIONAL, LONG-TERM SAFETY STUDY OF TZIELD® (TEPLIZUMAB-MZWV) IN PATIENTS WITH STAGE 2 TYPE 1 DIABETES

J
Jamie Felton
100 years or below
All genders
Observational
What is the purpose of this study?The purpose of this research is to collect general information on patients with stage 2 type 1 diabetes (T1D) and further information on the long-term effects of TZIELD® in patients with Stage 2 T1D, treated as per standard of care.  THIS STUDY IS ENROLLING BY …
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