A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Phase II/III randomized, double-blind, placebo-controlled, cognitiveendpoint, multicenter study of potential disease modifying therapies inindividuals at risk for and with dominantly inherited Alzheimer’s disease.
This is a two-part, multi-center, prospective longitudinal, exploratory study of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators and their impact in children with cystic fibrosis (CF) on endocrine growth factors and height, gastrointestinal function and gut microbiome, lung function and respiratory microbiome, liver and pancreatic function, sweat chloride, …
The objective of this study is to determine if early high volume intravenous fluiddministration (hyperhydration) may be effective in mitigating or preventing complications ofhiga toxin-producing E. coli (STEC) infection in children and adolescents when compared withditional approaches (conservative fluid management).
What is the purpose of this study?The main objective of this study is to determine if Home OCT-guided treatment results in 1) better visual acuity outcomes and/or 2) fewer number of injections over 104 weeks compared with treat and extend (T&E) dosing for nAMD.
What is the purpose of this study?Aim 1. Compare the effect of the Hypospadias Hub Intervention vs. control on the quality of SDM. Aim 2. Compare the effect of the Hypospadias Hub Decision Support Intervention vs. control on decisional conflict, decision-relevant knowledge, and decisional regret. Aim 3. Assess barriers and …
This study investigates the long-term effects of an investigational medication for Myotonic Dystrophy Type 1 (DM1). DM1 is a genetic disorder that affects muscle function and can cause muscle weakness and stiffness. This study aims to understand how the investigational medication affects people with DM1 over a long period.Participants will …
This study investigates the effects of two investigational medications, blinatumomab and nivolumab, in patients with B-cell acute lymphoblastic leukemia (B-ALL) that has relapsed. B-ALL is a type of cancer that affects the white blood cells. The study includes patients with Down syndrome and aims to compare the outcomes of using …
What is the purpose of this study?The DNA repair capacity (DRC) is a measure of a cell’s ability to repair DNA damage. High levels of DNA damage are observed in many lung diseases, including lung cancer and chronic obstructive lung disease (COPD, sometimes referred to as emphysema or chronic bronchitis). …
This study investigates the safety and effectiveness of combining an investigational medication with standard radiation therapy in treating children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG) or high-grade glioma (HGG). Glioma is a type of cancer that occurs in the brain or spine, and it is …
Are you or someone you know the mother of a young child (12-24 months)? JOIN OUR STUDY! Researchers at Purdue University are inviting volunteers to participate in a research project called Play and Learning Across a Year (PLAY). We want to learn more about what babies do at home. Participation …