Found 682 results for in-health
A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Phase III Trial of One vs. Two Years of Maintenance Olaparib, with or without Bevacizumab, in Patients with BRCA1/2 Mutated or Homologous Recombination Deficient (HRD+) Ovarian Cancer Following Response to First Line Platinum-Based Chemotherapy
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Jessica Parker Metter
What is the purpose of this study?This phase III trial compares the effect of olaparib for one year versus two years, with or without bevacizumab, for the treatment of BRCA 1/2 mutated or homologous recombination deficient stage III or IV ovarian cancer. Olaparib is a polyadenosine 5'-diphosphoribose polymerase (PARP) enzyme …
Gastric Per-Oral Endoscopic Myotomy (G-POEM) for the Treatment of Gastroparesis: A Database Repository
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Mohammad Al-Haddad, MD
What is the purpose of this study?The purpose of having a database is to collect data related to endoscopic procedures performed by Indiana University physicians specifically for the treatment of gastroparesis. This data will be used for research purposes only to determine the clinical impact of endoscopic treatments on gastroparesis. …
Oral manifestations of the severity of COVID-19
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Mythily Srinivasan
This study is being conducted to help determine whether specific proteins and other markers in saliva can predict development of taste changes, gum health and diabetes in previously coronavirus-2 infected patients with persistent symptoms or long COVID-19.
Organoid Model Predictive of Response to Immunotherapies
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Mateusz Opyrchal, MD, PhD
What is the purpose of this study?The purpose of this study is to create models out of tissue samples and treat those models with the same immunotherapy treatment the patient will be receiving, in order to validatehis process and to predict responses to therapies and use it to choose the …
Characteristics And Clinical Course Of Disease In Participants With Cardiomyopathy Associated With Friedreich Ataxia (Clarity-Fa)
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R. Mark Payne, MD
Study LX2006-02 is a prospective, longitudinal, low-intervention, multicenter, global study aimed at characterizing the nature and rate of cardiac disease progression in participants with genetically confirmed FA-CM.THIS STUDY IS ENROLLING BY INVITATION ONLY - Participants with a confirmed diagnosis of FA-CM, specifically identified by LVH by cMRI), will be contacted …
Adaptive Optics Gonioscopy In Vivo Imaging of the Effects of Rhopressa on the Trabecular Meshwork in Patients with Ocular Hypertension or Glaucoma
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Brett Joseph King
This is a prospective, randomized, single-masked study investigating the mechanism of action of Rhopressa (netarsudil) topical ophthalmic medication compared to a placebo drop (artificial tear). THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential participants with a diagnosis of ocular hypertension or open-angle glaucoma (excluding pigment dispersion) will be identified by …
Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma
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Brian Weiss
This phase II trial studies the effects of trastuzumab deruxtecan in treating patients with HER2 positive osteosarcoma that is newly diagnosed or has come back (recurrent). Trastuzumab deruxtecan is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug called deruxtecan. Trastuzumab attaches to HER2 positive cancer cells in a …
Healthy Females Needed To Help Develop A Vaccine for Chlamydia (IMPACT Study)
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Stephen Jordan
Chlamydia trachomatis (CT) is the most reported bacterial sexually transmitted infection (STI) in the United States. Untreated chlamydia infection in women can result in pelvic inflammatory disease, infertility, and/or ectopic pregnancy. Although chlamydia rates are at an all-time high, no vaccine is available because we don't yet understand how immunity to …
Hearing Health in Residents of Senior Living Facilities
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Irina Castellanos
The purpose of this study is to determine the prevalence rate of hearing loss and cerumen impaction in residents of senior living facilities and identify barriers to managing hearing devices and cerumen. Our long-term objective is to improve the effective identification and management of hearing health in senior living facilities. THIS …
Utilization of FibroScan in Fontan Associated Liver Disease prior to and after heart transplant or placement of single ventricle ventricular assist device
What is the purpose of this study?In this study, we propose to assess: 1) the role of FibroScan in patients with FALD prior to and after heart transplant or placement of single ventricle ventricular assist device (SVAD); 2) the association between liver stiffness measurement (LSM) from FibroScan and cardiac events, …
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