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Found 703 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating Pacing Methods for Heart Failure Treatment

T
Tony Navarrete
18 years - 100 years
All genders
Interventional
This study investigates two pacing methods for treating heart failure in patients with a specific heart condition. Heart failure is when the heart can't pump blood as well as it should. The study is comparing two types of cardiac-resynchronization therapy (CRT): biventricular pacing and pacing at the His or left …
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Investigation of Treatment Combinations for Advanced Non-Small Cell Lung Cancer

R
Rohan Maniar
18 years - 100 years
All genders
Phase 2/3
This study investigates the effects of adding an investigational medication, cemiplimab, to the usual treatment of docetaxel and ramucirumab for patients with stage IV or recurrent non-small cell lung cancer. This type of lung cancer is advanced and may have returned after previous treatment. Cemiplimab is a monoclonal antibody that …
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Alnylam ALN-APP-001: Phase I, placebo-controlled trial of ALN-APP in participants with Early-Onset Alzheimer’s disease

J
Jared Brosch, MD
18 years - 100 years
All genders
Phase 1
Interventional
Who is Eligible Ages 18+ Must have had symptoms of Alzheimer’s disease prior to age 65 Diagnosis of Alzheimer’s disease Must be able to complete MRI Must be able to tolerate lumbar puncture No history of seizures, stroke or cancer in the last 5 years What is Involved In-person visits …
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Prevalence and Predictors of Hepatic Steatosis in Persons Living With HIV

N
Naga Chalasani, MD
18 years - 80 years
All genders
Observational
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver conditions associated withumulation that ranges from benign, non-progressive liver fat accumulation to severever injury, cirrhosis, and liver failure. NAFLD is the most common liver disease in USdults and the second leading cause for liver transplantation in the US. The natural …
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A Non-interventional, Prospective, Multi-country Study Collecting Real-world Data on the Characteristics, Treatment Patterns, and Outcomes of Patients With Transthyretin (ATTR) Amyloidosis

N
Noel Dasgupta
18 years or above
All genders
Observational
What is the purpose of this study?MaesTTRo is an international, longitudinal, non-interventional study of adult patients with transthyretin (ATTR) amyloidosis. The MaesTTRo study aims to enroll a global cohort of patients with transthyretin (ATTR) amyloidosis to longitudinally observe the natural course of the disease and describe real-world treatment patterns and …
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Comparing Surgical and Non-Surgical Treatments for Pelvis Fractures

Y
Yohan Jang
60 years - 100 years
All genders
Interventional
This study investigates the effectiveness of early surgical treatment compared to non-surgical care with early rehabilitation for pelvis fractures. A pelvis fracture is a break in one or more of the bones of the pelvis. The study focuses on patients aged 60 years or older with a specific type of …
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Comparative Analysis of Extracellular Vesicles in Polycystic Ovary Syndrome (PCOS), Congenital Adrenal Hyperplasia (CAH), and Premature Adrenarche (PA)

E
Erica Eugster, MD
M
Manahil Mustafa
3 years - 18 years
Female
Observational
What is the purpose of this study?Extracellular vesicles (EVs) are double-membrane particles that transport proteins, microRNAs (miRNAs), and lipids, playing a crucial role in cell-to-cell communication and reflecting the cellular environment. Recent research has highlighted their potential as biomarkers and therapeutic agents in various adult conditions, yet their role in …
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Investigating Safety and Effects of Investigational Medications that Stop the Virus from Multiplying in HIV-1 Patients

S
Samir Gupta, MD
18 years - 100 years
All genders
Phase 1/2
Interventional
This study investigates the safety, pharmacokinetics, and antiviral activity of investigational antiretroviral agents in people living with HIV-1. The purpose is to understand how these agents affect the virus, which is responsible for HIV infection. Antiretrovirals are medications that stop the virus from multiplying, thereby managing the infection.Participants will receive …
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The Heart Outcomes in Pregnancy Expectations for Mom and Baby Study

C
Caroline Rouse, MD
18 years - 100 years
Female
Observational
This is a prospective, observational study which is evaluating the obstetrical, neonatal, and cardiovascular outcomes of 1000 pregnant people with known heart disease to define how best to structure cardio-obstetrics care to optimize outcomes.THIS STUDY IS ENROLLING BY INVITATION ONLY - This study is enrolling participants from specified community and …
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Investigational Medication for Chronic Kidney Disease and High Blood Pressure

S
Sharon Moe, MD
18 years - 100 years
All genders
Phase 3
Interventional
This study investigates how well an investigational medication works when combined with another medicine in people with chronic kidney disease (CKD) and high blood pressure (hypertension). CKD is a condition where the kidneys are damaged and can't filter blood as well as they should. Hypertension is when the blood pressure …
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