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Found 703 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Ovarian Tissue Cryopreservation for Fertility Preservation in Pre and Post-Pubertal Children, Adolescents and Adults Facing a Fertility Threatening Diagnosis or Treatment Regimen

A
Amanda J. Saraf, DO
17 years or below
Female
What is the purpose of this study?Define and follow-up with the patients that undergo OTC for fertility preservation.Optimize techniques and quality assurance measures for freezing and thawing of ovarian tissue or gametesEstablish techniques for in vitro follicle maturation (IFM) or in vitro maturation of cumulus oocyte complexesInvestigate factors affecting successful …
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In Vitro Expansion and Gene Transfer Using Peripheral Blood Stem Cells

S
Scott Goebel, MD
40 years or below
Accepts healthy volunteer
All genders
The purpose of this study is to determine whether the quantity of peripheral blood stem cells can be made greater in the laboratory. Healthy male and female volunteer donors between the ages of 18-40 years will be used as a source of normal peripheral blood hematopoietic stem cells (HSC). Health …
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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Program toEvaluate the Efficacy and Safety of Tulisokibart in Participants with Moderately to SeverelyActive Crohn's Disease

M
Monika Fischer, MD
16 years - 75 years
All genders
Phase 3
Interventional
What is the purpose of this study?The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. The protocol consists of 2 studies. Study 1 includes induction and maintenance treatment, and Study 2 includes only induction treatment. Each study …
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Study on Investigational Medication for Crohn's Disease

16 years - 80 years
All genders
Phase 3
Interventional
This study investigates the use of an investigational medication for people with moderately to severely active Crohn's disease, a condition that causes inflammation in the digestive tract. The investigational medication is a type of antibody that targets a protein involved in the immune response in the gut. The study aims …
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Impact of Intravitreal Pegcetacoplan Treatment on Systemic Complement Levels in Age Related Macular Degeneration: A pilot study

A
Amir Hajrasouliha
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This study aims to understand how a new eye treatment, Pegcetacoplan, affects levels of certain proteins in the blood (complement proteins) that are linked to age-related macular degeneration and to measure the progression rate of the disease based on OCT landmarks using standard pretrained …
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Investigating Long-term Safety of an Investigational Medication in Children with Crohn's Disease, Ulcerative Colitis, or Juvenile Psoriatic Arthritis

M
Marian Pfefferkorn
3 years or above
All genders
Phase 3
Interventional
This study investigates the long-term safety of an investigational medication in children with conditions like Crohn's disease, ulcerative colitis, or juvenile psoriatic arthritis. Crohn's disease and ulcerative colitis are types of inflammatory bowel diseases that cause inflammation in the digestive tract, while juvenile psoriatic arthritis is a type of arthritis …
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Study on Treatment for High-risk Renal Cell Carcinoma

J
Jennifer King
18 years - 100 years
All genders
This study investigates the effects of adding an investigational medication to a standard treatment for patients with high-risk renal cell carcinoma (RCC). RCC is a type of kidney cancer. The purpose of this study is to see if the investigational medication, when combined with the standard treatment, works better than …
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Evaluation of genetic mutations in African American with glaucoma associated with long anterior zonules (LAZ)

W
Weiming Mao
18 years - 100 years
All genders
Observational
What is the purpose of this study?Long anterior zonules (LAZ) is the presence of the zonular fibers (a tissue that holds the lens in place) attaching to the anterior part of the lens. LAZ is a rare disease and is genetically associated with certain gene mutations.  It has been reported …
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Investigating the Safety and Effects of an Investigational Medication in Autoimmune Kidney Diseases

M
Myda Khalid
10 years or above
All genders
Phase 2
Interventional
This study investigates the safety and effects of an investigational medication in people with autoimmune kidney diseases. These conditions include IgA Nephropathy (IgAN), Primary Membranous Nephropathy (pMN), and Minimal Change Disease/Focal Segmental Glomerulosclerosis (MCD/FSGS). Autoimmune kidney diseases occur when the body's defense system attacks the kidneys, causing damage. This study …
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Investigating Cognitive Impairment Detection in Alzheimer's Disease

N
Nicole Fowler
65 years - 100 years
Accepts healthy volunteer
All genders
This study investigates the use of a Passive Digital Marker (PDM) to identify people at risk of Mild Cognitive Impairment (MCI) and Alzheimer's Disease and Related Dementias (ADRD). The PDM is a tool that uses electronic medical records to find patients who might be at risk. Patients identified by the …
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