A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the long-term effects of an investigational medication in individuals with early Alzheimer's disease who have the APOE4/4 genotype. The APOE4/4 genotype is a specific genetic variation associated with an increased risk of Alzheimer's disease. The purpose of this investigation is to evaluate the safety and effectiveness of …
What is the purpose of this study?This study is researching an experimental drug called REGN7544 (called "study drug"). The study is focused on participants with POTS.The aim of the study is to see how safe, tolerable, and effective the study drug is.The study is looking at several other research questions, …
To evaluate PK after Saroglitazar Magnesium 1 mg dose on alternate days in subjects with moderate hepatic impairment with cirrhosis due to CLD based on Child-Pugh-Turcotte (CPT) score.To assess safety and tolerability of Sa-roglitazar Magnesium 1 mg dose on alter-nate days in subjects with moderate hepatic impairment with cirrhosis due …
What is the purpose of this study?Chronic liver disease (CLD) in children can be caused by a variety of conditions and have serious consequences if left untreated. Liver organoids are defined as 3D structure derived from human liver tissue and is a promising new approach to treating liver disease in …
This is a study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.The primary objective of this study is to evaluate the efficacy of IMVT-1402 versus placebo as assessed by T3 (total triiodothyronine [T3] or …
What is the purpose of this study?The purpose of this study is to better understand how pregnancies affected by severe Hemolytic Disease of the Fetus and Newborn (HDFN) are managed and what outcomes result from different treatment approaches. By analyzing past pregnancies from 2006 to 2023, this study aims to …
This study investigates the effects of an investigational medication on people with moderate to very severe Chronic Obstructive Pulmonary Disease (COPD). COPD is a long-term lung disease that makes it hard to breathe. The purpose of this study is to see how well the investigational medication works compared to a …
This is a multicenter study in pediatric patients aged 5 to 17 years with a primary diagnosis of Autism Spectrum Disorder associated with irritability to evaluate the efficacy of high and low doses of lumateperone compared to placebo for the treatment of irritability associated with Autism Spectrum Disorder and to …
This study investigates the safety and effects of using an investigational medication with irinotecan to treat young patients with solid tumors that have returned or not responded to treatment. Solid tumors are masses of tissue that form when cells grow uncontrollably. The investigational medication is designed to target and break …
