A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This is a two-part, multi-center, prospective longitudinal, exploratory study of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators and their impact in children with cystic fibrosis (CF) on endocrine growth factors and height, gastrointestinal function and gut microbiome, lung function and respiratory microbiome, liver and pancreatic function, sweat chloride, …
Who is Eligible Ages 18-80 Diagnosis of ALS with symptoms starting less than 18 months ago Able to swallow medication capsules No history of cancer within last 5 years No use of tracheostomy or almost continuous ventilator support What is Invovled In-person appointments at the IUH Neuroscience Center Participants will …
The objective of this study is to determine if early high volume intravenous fluiddministration (hyperhydration) may be effective in mitigating or preventing complications ofhiga toxin-producing E. coli (STEC) infection in children and adolescents when compared withditional approaches (conservative fluid management).
The purpose of this study is to determine if the use of image-guided, endovascular therapy (EVT) is an effective strategy with which to reduce Post Thrombotic Syndrome (PTS) diseaseverity and improve quality of life in patients with established disabling iliac-obstructivehrombotic syndrome (DIO-PTS).
What is the purpose of this study?The purpose of this research study is to evaluate the effectiveness of using a combination of pembrolizumab and olaparib when given before and after standard chemoradiation therapy in treating locally advanced head and neck squamous cell carcinoma. Pembrolizumab and olaparib are drugs that are …
What is the purpose of this study?The main objective of this study is to determine if Home OCT-guided treatment results in 1) better visual acuity outcomes and/or 2) fewer number of injections over 104 weeks compared with treat and extend (T&E) dosing for nAMD.
What is the purpose of this study?To evaluate the efficacy of divarasib compared with KRAS G12C inhibitors (sotorasib or adagrasib)To evaluate the efficacy of divarasib compared with KRAS G12C inhibitors (sotorasib or adagrasib)To evaluate, from the participant's perspective, the functioning and impact of key disease-related symptoms of participants treated with …
What is the purpose of this study?The purpose of this study to understand how patients cope with a hereditary cancer diagnosis, and what factors affect, either positively or negatively, the patient’s ability to cope with their diagnosis.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients …
What is the purpose of this study?Aim 1. Compare the effect of the Hypospadias Hub Intervention vs. control on the quality of SDM. Aim 2. Compare the effect of the Hypospadias Hub Decision Support Intervention vs. control on decisional conflict, decision-relevant knowledge, and decisional regret. Aim 3. Assess barriers and …
The purpose of the NAFLD Pediatric Database 2 is to better understand nonalcoholic fatty liver disease (''NAFLD) by following and evaluating children with this condition yearly.
