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Found 647 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

R
Raj Vuppalanchi, MD
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This clinical trial (a medical research study) is an open-label extension of a previous research study, SARO.21.001, which evaluates the efficacy (improvement in liver enzymes and lipid profiles) and safety (side effects) of Saroglitazar Magnesium in participants with a medical condition known as Primary …
T
Troy Markel, MD
110 years or below
All genders
Interventional
What is the purpose of this study?The main purpose of this study is to demonstrate acceptable performance and assess safety of the HARMONIC 700 Shears device in a post-market setting when used per the instructions for use in pediatric and adult surgical procedures.THIS STUDY IS ENROLLING BY INVITATION ONLY - …
L
Lisa Landrum, MD, PhD, MS
18 years - 100 years
Female
Phase 2
What is the purpose of this study?This is a clinical trial to test letrozole in patients with uterine leiomyosarcoma. The main question is will treatment with letrozole extend progression-free survival in patients. Patients will receive 2/5 mg of letrozole daily. Translational Objectives: 1. To preliminarily assess IHC hormone receptor expression and correlation …
N
Noel Dasgupta
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?To evaluate the efficacy and safety of a single dose of NTLA-2001 compared to placebo in participants with ATTR-CM. 
J
James Stevens
50 years - 85 years
All genders
Phase 3
Interventional
This study investigates the long-term effects of an investigational medication in individuals with early Alzheimer's disease who have the APOE4/4 genotype. The APOE4/4 genotype is a specific genetic variation associated with an increased risk of Alzheimer's disease. The purpose of this investigation is to evaluate the safety and effectiveness of …
A
Alex Barboi
18 years - 55 years
All genders
Phase 2
Interventional
What is the purpose of this study?This study is researching an experimental drug called REGN7544 (called "study drug"). The study is focused on participants with POTS.The aim of the study is to see how safe, tolerable, and effective the study drug is.The study is looking at several other research questions, …
R
Raj Vuppalanchi, MD
18 years - 80 years
All genders
Phase 1
Interventional
To evaluate PK after Saroglitazar Magnesium 1 mg dose on alternate days in subjects with moderate hepatic impairment with cirrhosis due to CLD based on Child-Pugh-Turcotte (CPT) score.To assess safety and tolerability of Sa-roglitazar Magnesium 1 mg dose on alter-nate days in subjects with moderate hepatic impairment with cirrhosis due …
C
Chao Jarasvaraparn
17 years or below
All genders
Observational
What is the purpose of this study?Chronic liver disease (CLD) in children can be caused by a variety of conditions and have serious consequences if left untreated. Liver organoids are defined as 3D structure derived from human liver tissue and is a promising new approach to treating liver disease in …
C
Cary Mariash, MD
18 years - 75 years
All genders
Phase 2/3
Interventional
This is a study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.The primary objective of this study is to evaluate the efficacy of IMVT-1402 versus placebo as assessed by T3 (total triiodothyronine [T3] or …
H
Hiba Mustafa, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to better understand how pregnancies affected by severe Hemolytic Disease of the Fetus and Newborn (HDFN) are managed and what outcomes result from different treatment approaches. By analyzing past pregnancies from 2006 to 2023, this study aims to …
581 - 590 of 647