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Found 723 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigation of the Efficacy and Safety of an Investigational Medication for Ulcerative Colitis

M
Monika Fischer, MD
18 years - 100 years
All genders
Phase 3
Interventional
This study investigates the efficacy and safety of an investigational medication in patients with moderately to severely active ulcerative colitis (UC). Ulcerative colitis is a chronic condition where the lining of the colon becomes inflamed and develops ulcers. The investigational medication is a monoclonal antibody that targets a specific protein …
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Empagliflozin and Physical Function in CKD (EMPA-FUNCTION) Feasibility Study

K
Kenneth Lim
18 years - 100 years
All genders
Interventional
What is the purpose of this study?The purpose of the study is to assess the therapeutic benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors in improving physical function in End Stage Renal disease (ESRD) patients.  The study is using the drug Empagliflozin, a FDA approved drug for patients with advanced CKD. …
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Attenuating DEPression with Internet CBT to Slow Cognitive Decline in Older ICU Survivors (ADEPT-ICU)

B
Babar Khan, MD
50 years - 100 years
All genders
Interventional
What is the purpose of this study?Depression affects one-third of intensive care unit (ICU) survivors and represents a potentially modifiable target to slow cognitive decline and reduce the risk of Alzheimer’s disease and related dementias (ADRD). Our multi-PI team proposes a two-arm RCT called ADEPT-ICU (Attenuating DEPression with Internet CBT …
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Investigating Music Interventions for Reducing Stress in Young Children Undergoing a Procedure to Replace Damaged Cells

S
Sheri Robb
3 years or below
All genders
This study investigates how music can help reduce stress in young children undergoing stem cell transplants and their parents. The purpose is to adapt a music-based intervention called Active Music Engagement (AME) for children under 3 years old and their parents. This adaptation aims to decrease distress and improve coping …
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Study on Safety and How Well Investigational Wound Dressing and Therapy Work

G
Greg Westin
22 years - 100 years
Accepts healthy volunteer
All genders
This study investigates the safety and effectiveness of an investigational wound dressing used with a special therapy for treating different types of wounds. The purpose is to gather information on how well the dressing and therapy work together after they have been approved for use. The study will include people …
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Investigation of a Treatment Being Tested for Preventing Episodic Migraine in Adults

M
Marlene Bultemeher
18 years - 100 years
All genders
Phase 3
Interventional
This study investigates the safety and effectiveness of an investigational medication compared to a placebo in preventing episodic migraines in adults. A migraine is a severe headache with throbbing pain, usually on one side of the head, often accompanied by nausea and sensitivity to light and sound. Episodic migraine is …
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A 2-Part, Multicenter, Randomized, Blinded, Active-Controlled Phase 2 Study to Sequentially Evaluate the Safety and Efficacy of BIIB091 Monotherapy and BIIB091 Combination Therapy With Diroximel Fumarate in Participants With Relapsing Forms of Multiple Sclerosis

A
Ajay Gupta
18 years - 55 years
All genders
Phase 2
Interventional
What is the purpose of this study?In this study, researchers will learn more about a study drug called BIIB091 in participants with MS who may be experiencing relapses. It is a 2-part study.In Part 1, one set of participants will take either BIIB091 or diroximel fumarate (DRF). In Part 2, …
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Investigating Long-Term Effects of Investigational Treatment in Phenylketonuria (PKU)

M
Melissa Lah, MD
100 years or below
All genders
Observational
This study investigates the effects of long-term treatment on people with phenylketonuria (PKU), a condition where the body cannot break down an amino acid called phenylalanine, which can lead to harmful levels in the body. The purpose of this study is to evaluate immune and inflammatory responses in participants receiving …
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A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF DNTH103 IN ADULTS WITH CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY (CAPTIVATE)

C
Cynthia Bodkin, MD
18 years - 75 years
All genders
Phase 3
Interventional
What is the purpose of this study?Study DNTH103-CIDP-301 is a global, multicenter, randomized, double-blind, placebo-controlled trial designedto evaluate the efficacy and safety of DNTH103 in adults with chronic inflammatory demyelinating polyneuropathy (CIDP). THIS STUDY IS ENROLLING BY INVITATION ONLY   
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Study of an Investigational Medication in Relapsing Multiple Sclerosis

A
Ajay Gupta
18 years - 55 years
All genders
Phase 3
Interventional
The purpose of this study is to compare the effectiveness and safety of an investigational medication to an existing treatment in adults with relapsing forms of multiple sclerosis (MS). Multiple sclerosis is a condition where the immune system mistakenly attacks the protective covering of nerves, leading to communication problems between …
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