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Found 687 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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R
Raj Vuppalanchi, MD
18 years - 75 years
All genders
Phase 3
Interventional
Why is this study being done?In some people, the liver makes an abnormal version of the alpha-1 antitrypsin (AAT) protein, called Z-AAT. Making an abnormal version of the AAT protein can result in liver disease as Z-AAT builds up in liver cells, which leads to liver problems such as liver …
C
Courtney Rowan, MD
1 years - 26 years
All genders
What is the purpose of this study?The goal of this study is to identify and validate response to therapy biomarkers for NIV respiratory support in children with ICCs. The central hypothesis is that response-to-therapy biomarkers can identify those most likely to benefit from intervention with NIV. The rationale is that …
M
Monika Fischer, MD
16 years - 75 years
All genders
Phase 3
Interventional
What is the purpose of this study?The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. The protocol consists of 2 studies. Study 1 includes induction and maintenance treatment, and Study 2 includes only induction treatment. Each study …
P
Paul Musey, MD
18 years - 55 years
All genders
Interventional
This study investigates the effects of an investigational medication on reducing acute stress reactions and acute stress disorder following a motor vehicle collision. Acute stress reactions are immediate psychological responses to a traumatic event, which can develop into acute stress disorder if symptoms persist. The purpose of this study is …
M
Monika Fischer, MD
18 years - 75 years
All genders
Phase 3
Interventional
This study investigates the use of an investigational medication for people with moderately to severely active Crohn's disease, a condition that causes inflammation in the digestive tract. The investigational medication is a type of antibody that targets a protein involved in the immune response in the gut. The study aims …
S
Sandeep Batra, MD
15 years - 20 years
All genders
This study investigates a home-based physical activity program designed for Hispanic or Latino/Latina adolescent and young adult (AYA) childhood cancer survivors. After cancer treatment, some AYA survivors may experience long-term effects like weight gain, tiredness, and reduced fitness. Hispanic or Latino/Latina survivors might face a higher risk of these effects. …
M
Marian Pfefferkorn
3 years or above
All genders
Phase 3
Interventional
This study investigates the long-term safety of an investigational medication in children with conditions like Crohn's disease, ulcerative colitis, or juvenile psoriatic arthritis. Crohn's disease and ulcerative colitis are types of inflammatory bowel diseases that cause inflammation in the digestive tract, while juvenile psoriatic arthritis is a type of arthritis …
M
Myda Khalid
10 years or above
All genders
Phase 2
Interventional
This study investigates the safety and effects of an investigational medication in people with autoimmune kidney diseases. These conditions include IgA Nephropathy (IgAN), Primary Membranous Nephropathy (pMN), and Minimal Change Disease/Focal Segmental Glomerulosclerosis (MCD/FSGS). Autoimmune kidney diseases occur when the body's defense system attacks the kidneys, causing damage. This study …
S
Sandeep Batra, MD
366 days - 42 years
All genders
Phase 3
This study investigates treatments for a type of blood cancer called Philadelphia chromosome-positive or ABL-class Philadelphia chromosome-like B-cell acute lymphoblastic leukemia (B-ALL). B-ALL is a cancer of the white blood cells. The study looks at the effects of combining blinatumomab, a special antibody that helps the immune system fight cancer, …
E
Eric Orman
18 years - 100 years
All genders
Phase 2
Interventional
This study investigates the effects of an investigational medication on hereditary hemochromatosis, a condition where the body absorbs too much iron from food, leading to excess iron storage in organs. The purpose of this study is to evaluate how the investigational medication affects liver iron concentration (LIC) in adults with …
561 - 570 of 687