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Found 649 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating Treatment for Children with Favorable Histology Wilms Tumors

M
Marissa Just
30 years or below
All genders
Phase 3
This study investigates treatment strategies for children with favorable histology Wilms tumors (FHWT), which is a common type of kidney cancer in children. The study aims to use risk factors, such as tumor histology, biology, and response to therapy, to determine the most effective treatment plan. Wilms Tumor is a …
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Investigating Long-Term Safety of an Investigational Treatment for Pompe Disease, a Rare Glycogen Storage Disorder

M
Melissa Lah, MD
18 years - 100 years
All genders
Observational
This study investigates the long-term safety of an investigational treatment for Pompe disease, a rare disorder caused by the buildup of a complex sugar called glycogen in the body's cells. The purpose is to gather information on potential risks associated with the treatment, including infusion-related reactions and medication errors.Participants will …
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Investigational Medication Study for Myotonic Dystrophy Type 1

L
Laurie Gutmann
18 years - 65 years
All genders
Interventional
This study investigates the effects of an investigational medication on individuals with Myotonic Dystrophy Type 1 (DM1). DM1 is a genetic disorder that affects muscle function, causing symptoms such as myotonia, which is a delayed relaxation of muscles after contraction. The purpose of this study is to assess the safety …
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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

K
Karl Shively
L
Luke A. Lopas, MD
18 years - 64 years
All genders
Phase 3
Interventional
The proposed study is a multi-center, prospective randomized controlled trial comparingurrent standard of care treatment to the SEXTANT treatment protocol in patients with Typeures of the tibia and IIIB fractures of the ankle and hindfoot.
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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

S
Sandeep Batra, MD
21 years or below
All genders
Phase 3
Interventional
What is the purpose of this study?This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acuteyeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop …
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Food Resources and Kitchen Skills plus Aerobic Training (FoRKS+) for Black Adults with Hypertension

Food Resources and Kitchen Skills plus Aerobic Training (FoRKS+) for Black Adults with Hypertension

D
Daniel Clark
35 years - 75 years
All genders
Interventional
FoRKS+ is a voluntary research study designed by researchers at the IU School of Medicine in partnership with Eskenazi Health to study the effect of brain-healthy foods and physical activity on cognition for Black adults with high blood pressure in the Eskenazi Health System.
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Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age

J
James Chmiel
1 year - 11 years
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the pharmacokinetics, safety, tolerability andy of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants with at1 triple combination responsive (TCR) mutation in the cystic fibrosis transmembraneductance regulator (CFTR) gene.
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Delivering Food Resources & Kitchen Skills (FoRKS) to Adults with Food Insecurity and Hypertension: An RCT

Delivering Food Resources & Kitchen Skills (FoRKS) to Adults with Food Insecurity and Hypertension: An RCT

D
Daniel Clark
35 years - 75 years
All genders
FoRKS is a voluntary research study designed by researchers at the IU School of Medicine in partnership with Eskenazi Health. The purpose of FoRKS is to study the effect increased food resources and kitchen skills have on health and nutrition for adults with high blood pressure in the Eskenazi Health …
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Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder

L
Leslie Hulvershorn, MD, MSc
10 years - 17 years
All genders
Phase 3
Interventional
This study investigates the safety and tolerability of an investigational medication in young people with schizophrenia or bipolar disorder. Schizophrenia is a mental disorder that affects how a person thinks, feels, and behaves. Bipolar disorder is a condition that causes extreme mood swings, including emotional highs (mania or hypomania) and …
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A Multicenter, Open-Label, Extension Clinical trial to evaluate Safety and Efficacy of Saroglitazar Magnesium in Participants with Primary Biliary Cholangitis (PBC)

R
Raj Vuppalanchi, MD
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This clinical trial (a medical research study) is an open-label extension of a previous research study, SARO.21.001, which evaluates the efficacy (improvement in liver enzymes and lipid profiles) and safety (side effects) of Saroglitazar Magnesium in participants with a medical condition known as Primary …
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