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Found 701 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating the Effectiveness of Immunotherapy in Recurrent Endometrial Cancer

L
Lisa Landrum, MD, PhD, MS
18 years - 100 years
Female
Phase 2
This study investigates the effectiveness of using a combination of investigational medications, nivolumab and ipilimumab, compared to nivolumab alone in treating patients with recurrent endometrial cancer. Endometrial cancer is a type of cancer that begins in the lining of the uterus. This study focuses on a specific type of endometrial …
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Investigating Chemoradiation (Combination of Chemotherapy and Radiation Therapy) for Early Stage Vulvar Cancer

S
Sharon E. Robertson
18 years - 100 years
Female
Phase 2
This study investigates the safety of using chemoradiation instead of surgery for early stage vulvar cancer. Vulvar cancer is a type of cancer that affects the external female genitalia. In some cases, cancer spreads to nearby lymph nodes. This study looks at patients with a macrometastasis, which means the cancer …
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Study on Safety and Effects of Investigational Antibiotic in Infants

A
Anna Elizabeth Thomas
9 months or below
All genders
Phase 1/2
Interventional
This study investigates the safety and effects of an investigational medication for treating infections caused by gram-negative bacteria in newborns and infants. Gram-negative bacteria are a type of bacteria that can cause various infections and are known for their resistance to antibiotics. The investigational medication is a combination of two …
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Comparing Surgical and Non-Surgical Treatments for Pelvis Fractures

Y
Yohan Jang
60 years - 100 years
All genders
Interventional
This study investigates the effectiveness of early surgical treatment compared to non-surgical care with early rehabilitation for pelvis fractures. A pelvis fracture is a break in one or more of the bones of the pelvis. The study focuses on patients aged 60 years or older with a specific type of …
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Studying the Safety and Effectiveness of Bladder-Administered Therapy for BCG-Unresponsive Bladder Cancer

H
Hristos Kaimakliotis, MD
18 years - 100 years
All genders
Phase 2
This study investigates the safety and efficacy of intravesical nadofaragene firadenovec, either alone or in combination with chemotherapy or immunotherapy, in patients with high-grade Bacillus Calmette-Guerin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC). NMIBC is a type of bladder cancer that has not spread into the muscle layer of the …
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Comparative Analysis of Extracellular Vesicles in Polycystic Ovary Syndrome (PCOS), Congenital Adrenal Hyperplasia (CAH), and Premature Adrenarche (PA)

E
Erica Eugster, MD
M
Manahil Mustafa
3 years - 18 years
Female
Observational
What is the purpose of this study?Extracellular vesicles (EVs) are double-membrane particles that transport proteins, microRNAs (miRNAs), and lipids, playing a crucial role in cell-to-cell communication and reflecting the cellular environment. Recent research has highlighted their potential as biomarkers and therapeutic agents in various adult conditions, yet their role in …
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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

J
Jonathan L. Berkowitz, MD, PhD
18 years or above
All genders
Interventional
This randomized research trial studies how well serum tumor marker directed disease monitoring works in monitoring patients with hormone receptor positive Her2 negative breast cancer that has spread to other places in the body. Using markers to prompt when scans should be ordered may be as good as the usual …
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Study of a Medication for Liver Disease in People with HIV

S
Samer Gawrieh, MD
18 years - 100 years
All genders
Interventional
This study investigates the effects of an investigational medication on people with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) who also have Human Immunodeficiency Virus (HIV). MASLD is a condition where fat builds up in the liver, and this study aims to see if the investigational medication can reduce this fat. …
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Studying the Effects of an Investigational Medication in Breast Cancer

R
Rina Yadav
18 years or above
Female
Phase 2
This study investigates the effects of an investigational medication on premenopausal women with a specific type of breast cancer called estrogen receptor-positive, HER2-negative breast cancer. The purpose of the study is to understand how the investigational medication affects tumor cell growth compared to other treatments. The study is divided into …
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Biological Sample Collection for Glaucoma Research

W
Weiming Mao
18 years - 100 years
All genders
Observational
The purpose of this study is to help scientists to study glaucoma.
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571 - 580 of 701