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Found 703 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Patients With Graves' Disease

C
Cary Mariash, MD
18 years - 75 years
All genders
Phase 2/3
Interventional
This is a study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.The primary objective of this study is to evaluate the efficacy of IMVT-1402 versus placebo as assessed by T3 (total triiodothyronine [T3] or …
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A Historical Cohort, Multicenter Study to Characterize the Management, Clinical Course, and Outcomes of Pregnancies in Participants Who Have Experienced a Pregnancy With Severe HDFN

H
Hiba Mustafa, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to better understand how pregnancies affected by severe Hemolytic Disease of the Fetus and Newborn (HDFN) are managed and what outcomes result from different treatment approaches. By analyzing past pregnancies from 2006 to 2023, this study aims to …
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Investigating the Effects of an Investigational Medication on Long-term Lung Disease (COPD)

M
Marc Rovner
18 years - 100 years
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication on people with moderate to very severe Chronic Obstructive Pulmonary Disease (COPD). COPD is a long-term lung disease that makes it hard to breathe. The purpose of this study is to see how well the investigational medication works compared to a …
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Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients

L
Leslie Hulvershorn, MD, MSc
5 years - 17 years
All genders
Interventional
This is a multicenter study in pediatric patients aged 5 to 17 years with a primary diagnosis of Autism Spectrum Disorder associated with irritability to evaluate the efficacy of high and low doses of lumateperone compared to placebo for the treatment of irritability associated with Autism Spectrum Disorder and to …
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Detecting Prostate Cancer Return with Imaging

C
Clinton Bahler, MD
18 years - 100 years
Male
Phase 3
This study investigates how well a special scan can find prostate cancer that has come back after treatment. Prostate cancer is a disease where cells in the prostate grow out of control. The study uses a technique called PET/CT, which stands for Positron Emission Tomography and Computed Tomography. This scan …
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Investigating Sleep and Daily Living in Patients with Dravet Syndrome and Lennox-Gastaut Syndrome (Severe Epilepsy Disorders)

J
Jason Santiago
18 years - 100 years
All genders
Observational
This study investigates sleep disturbances, behavior, and daily activities in patients with Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS) who are starting treatment with an investigational medication. Dravet Syndrome and Lennox-Gastaut Syndrome are conditions that affect the brain and can cause seizures. This study looks at how the treatment affects …
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Study on Preventing Bronchopulmonary Dysplasia in Premature Infants

A
Anna Elizabeth Thomas
23 weeks - 27 weeks
All genders
Phase 2
Interventional
This study investigates bronchopulmonary dysplasia in extremely premature infants. Bronchopulmonary dysplasia is a serious lung condition that affects infants, particularly those born prematurely, causing breathing problems. The purpose of this study is to determine if an investigational medication can prevent this condition when compared to standard neonatal care.Participants in the …
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Studying Heart Health and Knowledge in Men with Prostate Cancer

S
Suparna C. Clasen, MD, MSCE
J
Jordan Holmes
18 years - 100 years
Male
This study investigates cardiovascular health literacy and risk among men with prostate cancer. The purpose is to compare these factors between African American and White men who are receiving or have completed androgen deprivation therapy, which is a treatment that reduces male hormones to slow cancer growth. The study also …
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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

S
Sandeep Batra, MD
1 month - 21 years
All genders
Phase 3
Interventional
What is the purpose of this study?Rhabdomyosarcoma is a type of cancer that occurs in the soft tissues in the body. This phaseutcomes in patients with very low risk rhabdomyosarcoma (VLR-RMS) while decreasing the burden of therapy using treatment with 24 weeks of vincristined dactinomycin (VA) and examines the use …
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Investigating Levocarnitine for Reducing Liver Issues in Leukemia Treatment

R
Rachael Schulte
15 years - 40 years
All genders
This study investigates whether adding levocarnitine to chemotherapy regimens can reduce liver problems, specifically conjugated hyperbilirubinemia, in adolescents and young adults with Acute Lymphoblastic Leukemia (ALL). Conjugated hyperbilirubinemia is a condition where there is too much bilirubin, a substance made during the breakdown of red blood cells, in the blood. …
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