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Found 699 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Detecting Prostate Cancer Return with Imaging

C
Clinton Bahler, MD
18 years - 100 years
Male
Phase 3
This study investigates how well a special scan can find prostate cancer that has come back after treatment. Prostate cancer is a disease where cells in the prostate grow out of control. The study uses a technique called PET/CT, which stands for Positron Emission Tomography and Computed Tomography. This scan …
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Investigating Sleep and Daily Living in Patients with Dravet Syndrome and Lennox-Gastaut Syndrome (Severe Epilepsy Disorders)

J
Jason Santiago
18 years - 100 years
All genders
Observational
This study investigates sleep disturbances, behavior, and daily activities in patients with Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS) who are starting treatment with an investigational medication. Dravet Syndrome and Lennox-Gastaut Syndrome are conditions that affect the brain and can cause seizures. This study looks at how the treatment affects …
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Study on Preventing Bronchopulmonary Dysplasia in Premature Infants

A
Anna Elizabeth Thomas
23 weeks - 27 weeks
All genders
Phase 2
Interventional
This study investigates bronchopulmonary dysplasia in extremely premature infants. Bronchopulmonary dysplasia is a serious lung condition that affects infants, particularly those born prematurely, causing breathing problems. The purpose of this study is to determine if an investigational medication can prevent this condition when compared to standard neonatal care.Participants in the …
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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

S
Sandeep Batra, MD
1 month - 21 years
All genders
Phase 3
Interventional
What is the purpose of this study?Rhabdomyosarcoma is a type of cancer that occurs in the soft tissues in the body. This phaseutcomes in patients with very low risk rhabdomyosarcoma (VLR-RMS) while decreasing the burden of therapy using treatment with 24 weeks of vincristined dactinomycin (VA) and examines the use …
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Investigating Levocarnitine for Reducing Liver Issues in Leukemia Treatment

R
Rachael Schulte
15 years - 40 years
All genders
This study investigates whether adding levocarnitine to chemotherapy regimens can reduce liver problems, specifically conjugated hyperbilirubinemia, in adolescents and young adults with Acute Lymphoblastic Leukemia (ALL). Conjugated hyperbilirubinemia is a condition where there is too much bilirubin, a substance made during the breakdown of red blood cells, in the blood. …
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Ovarian Tissue Cryopreservation for Fertility Preservation in Pre and Post-Pubertal Children, Adolescents and Adults Facing a Fertility Threatening Diagnosis or Treatment Regimen

A
Amanda J. Saraf, DO
17 years or below
Female
What is the purpose of this study?Define and follow-up with the patients that undergo OTC for fertility preservation.Optimize techniques and quality assurance measures for freezing and thawing of ovarian tissue or gametesEstablish techniques for in vitro follicle maturation (IFM) or in vitro maturation of cumulus oocyte complexesInvestigate factors affecting successful …
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In Vitro Expansion and Gene Transfer Using Peripheral Blood Stem Cells

S
Scott Goebel, MD
40 years or below
Accepts healthy volunteer
All genders
The purpose of this study is to determine whether the quantity of peripheral blood stem cells can be made greater in the laboratory. Healthy male and female volunteer donors between the ages of 18-40 years will be used as a source of normal peripheral blood hematopoietic stem cells (HSC). Health …
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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Program toEvaluate the Efficacy and Safety of Tulisokibart in Participants with Moderately to SeverelyActive Crohn's Disease

M
Monika Fischer, MD
16 years - 75 years
All genders
Phase 3
Interventional
What is the purpose of this study?The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. The protocol consists of 2 studies. Study 1 includes induction and maintenance treatment, and Study 2 includes only induction treatment. Each study …
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Impact of Intravitreal Pegcetacoplan Treatment on Systemic Complement Levels in Age Related Macular Degeneration: A pilot study

A
Amir Hajrasouliha
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This study aims to understand how a new eye treatment, Pegcetacoplan, affects levels of certain proteins in the blood (complement proteins) that are linked to age-related macular degeneration and to measure the progression rate of the disease based on OCT landmarks using standard pretrained …
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Investigating Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult (AYA) Childhood Cancer Survivors

S
Sandeep Batra, MD
15 years - 20 years
All genders
This study investigates a home-based physical activity program designed for Hispanic or Latino/Latina adolescent and young adult (AYA) childhood cancer survivors. After cancer treatment, some AYA survivors may experience long-term effects like weight gain, tiredness, and reduced fitness. Hispanic or Latino/Latina survivors might face a higher risk of these effects. …
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