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Found 728 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Long-Term Effects of an Investigational Medication for Myotonic Dystrophy Type 1 (DM1)

A
Adam Comer
16 years - 17 years
All genders
Phase 3
Interventional
This study investigates the long-term effects of an investigational medication for Myotonic Dystrophy Type 1 (DM1). DM1 is a genetic disorder that affects muscle function and can cause muscle weakness and stiffness. This study aims to understand how the investigational medication affects people with DM1 over a long period.Participants will …
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Study of Treatments for Relapsed B-Cell Acute Lymphoblastic Leukemia

S
Sandeep Batra, MD
1 year - 30 years
All genders
Phase 2
This study investigates the effects of two investigational medications, blinatumomab and nivolumab, in patients with B-cell acute lymphoblastic leukemia (B-ALL) that has relapsed. B-ALL is a type of cancer that affects the white blood cells. The study includes patients with Down syndrome and aims to compare the outcomes of using …
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Analysis of DRC in lung disease

C
Catherine Sears, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?The DNA repair capacity (DRC) is a measure of a cell’s ability to repair DNA damage. High levels of DNA damage are observed in many lung diseases, including lung cancer and chronic obstructive lung disease (COPD, sometimes referred to as emphysema or chronic bronchitis). …
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Study of Investigational Medication with Radiation Therapy for Diagnosed Brain Tumors

S
Sandeep Batra, MD
12 months - 21 years
All genders
Phase 1/2
Interventional
This study investigates the safety and effectiveness of combining an investigational medication with standard radiation therapy in treating children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG) or high-grade glioma (HGG). Glioma is a type of cancer that occurs in the brain or spine, and it is …
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Mothers of Young Children Needed for PLAY Reseach Study!

Mothers of Young Children Needed for PLAY Reseach Study!

Laura Claxton
2 years or below
Accepts healthy volunteer
All genders
Are you or someone you know the mother of a young child (12-24 months)? JOIN OUR STUDY! Researchers at Purdue University are inviting volunteers to participate in a research project called Play and Learning Across a Year (PLAY). We want to learn more about what babies do at home. Participation …
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A Non-randomized Open-label Multi-center Phase I/II Study of Phosphatidylinositol-3-kinase (PI3K) Inhibitor Copanlisib in Pediatric Patients With Relapsed/Refractory Solid Tumors or Lymphoma

J
James Croop, MD, PhD
1 years - 21 years
All genders
This study is designed to investigate whether the use of copanlisib is safe, feasible and beneficial to pediatric patients with solid solid tumors or lymphoma that are recurrent or refractory to standard therapy.
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A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

N
Noel Dasgupta
18 years or above
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the safety and tolerability of extended dosing withwith hereditary transthyretin-mediated amyloid polyneuropathy (hATTR-PN).
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Research Study on the Safety and Effects of an Investigational Medication with Radiation in Children with High Grade Glioma

B
Brian Weiss
12 months - 22 years
All genders
Phase 1
This study investigates the safety and effects of an investigational medication when combined with radiation therapy in children with high grade glioma. High grade glioma is a type of cancer that occurs in the brain. The investigational medication works by blocking signals that make cancer cells grow, which may help …
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Studying Special Bandages for Hard-to-Heal Wounds

M
Mithun Sinha
18 years - 100 years
All genders
Interventional
This study investigates the effects of using a tri-layer amnion graft or a single-layer amnion graft for patients with hard-to-heal diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs). These ulcers are wounds that are difficult to heal and may require special treatments. The study compares these treatments to a …
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Investigating Pacing Methods for Heart Failure Treatment

T
Tony Navarrete
18 years - 100 years
All genders
Interventional
This study investigates two pacing methods for treating heart failure in patients with a specific heart condition. Heart failure is when the heart can't pump blood as well as it should. The study is comparing two types of cardiac-resynchronization therapy (CRT): biventricular pacing and pacing at the His or left …
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