Found 713 in-health trials
A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Dillon O'Neill
The purpose of this study is to investigate the effectiveness of two surgical treatments for hip fractures: arthroplasty and internal fixation. A hip fracture is a break in the upper part of the thigh bone near the hip joint. This study focuses on patients with minimally displaced femoral neck fractures, …
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Bryan Schneider, MD
This study investigates treatments for patients with residual triple negative breast cancer, a type of breast cancer that does not have estrogen, progesterone, or HER2 receptors. The study uses circulating tumor DNA (ctDNA) to assign participants to different treatment arms based on their genomic markers. Participants with ctDNA positivity and …
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Sandeep Batra, MD
This study investigates treatment options for children and young adults with low-grade glioma (LGG), a type of brain tumor. The purpose of this study is to compare the effects of an investigational medication with standard chemotherapy treatments, carboplatin and vincristine, in patients who do not have a specific genetic mutation …
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Nasser Hanna, MD
This study investigates the use of circulating tumor DNA (ctDNA) to personalize treatment for patients with stage III non-small cell lung cancer (NSCLC). The purpose is to use ctDNA analysis to guide therapy decisions, instead of relying solely on clinical or radiographic evidence of disease. This approach aims to tailor …
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Jared Brosch, MD
What is the purpose of this study?To assess the safety, tolerability, biomarker, cognitive, and clinical efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with the study drug improves disease-related biomarkers and slows the rate of progression of cognitive or clinical impairment.THIS STUDY IS …
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Mateusz Opyrchal, MD, PhD
What is the purpose of this study?Phase 1a Dose Escalation/Cohort Expansion BBO-10203 Monotherapy Primary: To evaluate the safety and tolerability of BBO-10203, an inhibitor of the PI3Kα:RAS interaction, in subjects with locally advanced unresectable or metastatic (ie, advanced) HER2-positive BC; HR-positive, HER2-negative BC; KRAS mutant NSCLC; and KRAS mutant CRC. Secondary: To evaluate …
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Timothy Masterson
This study investigates two different surgical techniques for treating testis cancer, focusing on retroperitoneal lymph node dissection (RPLND). The study compares the transperitoneal (TP) and extraperitoneal (EP) approaches. RPLND is a surgery to remove lymph nodes from the back of the abdomen. The purpose is to see if the EP …
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Susan Conroy, MD PhD
Still searching for relief from depression? Have you tried multiple treatments for depression without success? You may have another option. When treatments haven’t worked, research may offer a new path. The Abbott TRANSCEND study is a research study for adults with depression who have not felt better after trying at least …
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Michelle C. Starr, MD
The purpose of this study is to investigate patterns of angiogenesis biomarkers in premature infants. Angiogenesis is the process by which new blood vessels form from pre-existing vessels. This study will look at these patterns in infants with and without lung disease, such as bronchopulmonary dysplasia (BPD), a condition often …
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Shelley Johns
What is the purpose of this study?In this 3-phase pilot, we will identify adverse health outcomes and unmet support needs of testicular cancer survivors (TCS) (Phase 1) and employ participatory co-design to adapt an existing acceptance and commitment therapy (ACT)-based intervention with a sample of up to 8 TCS (Phase …
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