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Found 698 in-health trials
A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Jared Brosch, MD
What is the purpose of this study?To assess the safety, tolerability, biomarker, cognitive, and clinical efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with the study drug improves disease-related biomarkers and slows the rate of progression of cognitive or clinical impairment.THIS STUDY IS …
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Kathryn Nevel
This study investigates the effectiveness and safety of an investigational medication for people with IDH1-mutant glioma, a type of brain tumor. Gliomas are graded based on their severity, with Grade 2 and Grade 3 being less severe than Grade 4. The study has three parts: Part 1 looks at different …
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Marianne Matthias
What is the purpose of this study?This is phase 2 of a two-phase project with the overarching goal of testing a decision aid paired with coaching sessions, tailored to Black patients with comorbid chronic pain and depression. The decision aid/coaching sessions are designed to help people learn more about other …
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Mateusz Opyrchal, MD, PhD
What is the purpose of this study?Phase 1a Dose Escalation/Cohort Expansion BBO-10203 Monotherapy Primary: To evaluate the safety and tolerability of BBO-10203, an inhibitor of the PI3Kα:RAS interaction, in subjects with locally advanced unresectable or metastatic (ie, advanced) HER2-positive BC; HR-positive, HER2-negative BC; KRAS mutant NSCLC; and KRAS mutant CRC. Secondary: To evaluate …
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Timothy Masterson
This study investigates two different surgical techniques for treating testis cancer, focusing on retroperitoneal lymph node dissection (RPLND). The study compares the transperitoneal (TP) and extraperitoneal (EP) approaches. RPLND is a surgery to remove lymph nodes from the back of the abdomen. The purpose is to see if the EP …
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Michelle C. Starr, MD
The purpose of this study is to investigate patterns of angiogenesis biomarkers in premature infants. Angiogenesis is the process by which new blood vessels form from pre-existing vessels. This study will look at these patterns in infants with and without lung disease, such as bronchopulmonary dysplasia (BPD), a condition often …
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Kathy Miller, MD
This study investigates ways to support people with breast cancer who are taking oral anticancer medications. Breast cancer is a disease where cells in the breast grow out of control. Oral anticancer medications are drugs taken by mouth to help treat cancer. The purpose of this study is to develop …
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Viral Shah
This study investigates the performance of sensors in people with Type 1 and Type 2 diabetes. Type 1 diabetes is a chronic disease where the body's defense system mistakenly attacks specific cells within the pancreas, which make insulin. Insulin helps control sugar in the blood. When these cells are damaged, …
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Faith Zor
This study investigates genetic factors that may cause some severely burned patients to have high levels of lactic acid in their blood. Lactic acid is a substance that builds up in the blood when the body does not have enough oxygen to break down glucose for energy. The purpose of …
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Bryan Schneider, MD
What is the purpose of this study?This Phase III, randomized, open-label, multicenter study will evaluate the efficacy andy of giredestrant plus everolimus compared with the physician's choice of endocrineherapy plus everolimus in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer …
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