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Found 702 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigation of Advanced Imaging Techniques for Prostate Cancer Detection Using PSMA PET and MRI

C
Clinton Bahler, MD
18 years - 100 years
Male
This study investigates the use of advanced imaging techniques like PSMA PET combined with MRI to detect prostate cancer. Prostate cancer is a disease where cells in the prostate grow out of control. The study compares these imaging techniques to the standard of care in identifying prostate cancer in men …
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Phase Ib Active Immunotherapy Trial (Expansion) with a Combination of Two Chimeric (Trastuzumab-like and Pertuzumab-like) HER-2 B Cell Peptide Vaccine emulsified in ISA 720 Adjuvant in Patients with Advanced Solid Tumors

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 1/2
What is the purpose of this study?This phase I trial studies the side effects and best dose of vaccine therapy in treating patients with metastatic solid tumors. Vaccines made from antibodies and peptides combined with tumor cells may help the body build an effective immune response to kill tumor cells.THIS …
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Master Screening and Reassessment Protocol (MSRP) for TierAdvancement in the NCI myeloMATCH Clinical Trials

R
Rita Assi
18 years - 100 years
All genders
What is the purpose of this study?This MyeloMATCH Master Screening and Reassessment Protocol (MSRP) evaluates the use of a screening tool and specific laboratory tests to help improve participants' ability to register to clinical trials throughout the course of their myeloid cancer (acute myeloid leukemia or myelodysplastic syndrome) treatment. This …
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Study on Effects of Investigational for Refractory Metastatic Colorectal Cancer in Minority Populations

A
Anita Turk, MD
18 years - 100 years
All genders
Phase 4
This study investigates the effects of an investigational medication on high blood pressure in patients with refractory metastatic colorectal cancer (mCRC) from minority groups, specifically Black/African American and Hispanic/Latino populations. High blood pressure, also known as hypertension, is when the force of blood against the artery walls is too high, …
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Investigating the Safety and Effects of an Investigational Antibody-Drug Conjugate in Solid Tumors

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 1
This study investigates the safety and effects of an investigational antibody-drug conjugate in patients with advanced or metastatic solid tumors. The purpose is to understand how the investigational medication works in the body and its impact on tumors. Advanced or metastatic solid tumors are cancers that have spread beyond their …
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Investigating the Safety of an Investigational Treatment for a Type of Cancer Affecting White Blood Cells

H
Huda Salman
18 years - 100 years
All genders
Phase 1
This study investigates the safety of an investigational treatment using special immune cells called CAR-T cells for people with certain B cell cancers. B cell malignancies are cancers that affect a type of white blood cell. The study includes participants whose cancer has returned or not responded to previous treatments. …
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Investigating Treatment Options for a Type of Prostate Cancer with PSMA Protein

N
Nabil Adra, MD
18 years - 100 years
Male
Phase 2/3
This study investigates the treatment of PSMA-positive metastatic castration-resistant prostate cancer (mCRPC) using an investigational medication called AAA817. The purpose of this study is to compare the effects of AAA817 with the standard of care treatment in adults who have already been treated with certain cancer therapies but have not …
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Studying Memory Talk Therapy for Older Adults with Memory Problems

M
Malaz Boustani, MD
65 years - 100 years
All genders
Interventional
This study investigates the use of Smart Virtual Reminiscence (SVR) therapy for older adults with Alzheimer's Disease and Related Dementias (ADRD). ADRD can cause changes in behavior and mood, known as Behavioral and Psychological Symptoms of Dementia (BPSD), like agitation or depression. The SVR therapy is a computer program that …
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

G
Gregory Sokol, MD
20 years or below
Accepts healthy volunteer
All genders
The study investigators are interested in learning more about how drugs, that are given tohildren by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of thisudy is to evaluate the …
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Testing the Addition of Chemotherapy Drug, Cisplatin, to Usual Radiation Therapy for Patients with Head and Neck Cancer

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 2
Interventional
The purpose of this study is to compare two treatment approaches that are currently used after surgery for head and neck cancer. One approach is to administer radiation therapy alone. A second approach is to administer radiation therapy along with the chemotherapy drug, cisplatin.
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