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Found 687 in-health trials
A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Nasser Hanna, MD
This study investigates the use of circulating tumor DNA (ctDNA) to personalize treatment for patients with stage III non-small cell lung cancer (NSCLC). The purpose is to use ctDNA analysis to guide therapy decisions, instead of relying solely on clinical or radiographic evidence of disease. This approach aims to tailor …
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Jared Brosch, MD
What is the purpose of this study?To assess the safety, tolerability, biomarker, cognitive, and clinical efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with the study drug improves disease-related biomarkers and slows the rate of progression of cognitive or clinical impairment.THIS STUDY IS …
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Jennifer King
This study investigates treatments for advanced clear cell renal cell carcinoma, a type of kidney cancer. The purpose of this study is to compare the effects of an investigational medication combined with cabozantinib versus a placebo combined with cabozantinib. Participants in this study have advanced or metastatic clear cell renal …
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Mateusz Opyrchal, MD, PhD
What is the purpose of this study?Phase 1a Dose Escalation/Cohort Expansion BBO-10203 Monotherapy Primary: To evaluate the safety and tolerability of BBO-10203, an inhibitor of the PI3Kα:RAS interaction, in subjects with locally advanced unresectable or metastatic (ie, advanced) HER2-positive BC; HR-positive, HER2-negative BC; KRAS mutant NSCLC; and KRAS mutant CRC. Secondary: To evaluate …
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Timothy Masterson
This study investigates two different surgical techniques for treating testis cancer, focusing on retroperitoneal lymph node dissection (RPLND). The study compares the transperitoneal (TP) and extraperitoneal (EP) approaches. RPLND is a surgery to remove lymph nodes from the back of the abdomen. The purpose is to see if the EP …
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Michelle C. Starr, MD
The purpose of this study is to investigate patterns of angiogenesis biomarkers in premature infants. Angiogenesis is the process by which new blood vessels form from pre-existing vessels. This study will look at these patterns in infants with and without lung disease, such as bronchopulmonary dysplasia (BPD), a condition often …
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Brian Weiss
This phase II trial studies the effects of trastuzumab deruxtecan in treating patients with HER2 positive osteosarcoma that is newly diagnosed or has come back (recurrent). Trastuzumab deruxtecan is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug called deruxtecan. Trastuzumab attaches to HER2 positive cancer cells in a …
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Tarah Ballinger, MD
This study investigates the use of the NearWave optical molecular monitoring system to track the progress of breast cancer treatment. The purpose is to see if this system can predict how well patients respond to chemotherapy before surgery. Breast cancer is a disease where cells in the breast grow uncontrollably. …
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Misty D. Shields, MD, PhD
This study investigates the effects of a combination of investigational medications in treating non-small cell lung cancer (NSCLC) that has transformed into small cell lung cancer (SCLC). NSCLC is a type of lung cancer that starts in the cells lining the lungs, while SCLC is a faster-growing form of lung …
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Kathy Miller, MD
This study investigates ways to support people with breast cancer who are taking oral anticancer medications. Breast cancer is a disease where cells in the breast grow out of control. Oral anticancer medications are drugs taken by mouth to help treat cancer. The purpose of this study is to develop …
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