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Found 723 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients

L
Leslie Hulvershorn, MD, MSc
5 years - 17 years
All genders
Interventional
This is a multicenter study in pediatric patients aged 5 to 17 years with a primary diagnosis of Autism Spectrum Disorder associated with irritability to evaluate the efficacy of high and low doses of lumateperone compared to placebo for the treatment of irritability associated with Autism Spectrum Disorder and to …
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Investigational Study for Relapsed or Refractory Solid Tumors in Young Patients

B
Brian Weiss
1 years - 39 years
All genders
Phase 1/2
This study investigates the safety and effects of using an investigational medication with irinotecan to treat young patients with solid tumors that have returned or not responded to treatment. Solid tumors are masses of tissue that form when cells grow uncontrollably. The investigational medication is designed to target and break …
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Investigating Sleep and Daily Living in Patients with Dravet Syndrome and Lennox-Gastaut Syndrome (Severe Epilepsy Disorders)

J
Jason Santiago
18 years - 100 years
All genders
Observational
This study investigates sleep disturbances, behavior, and daily activities in patients with Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS) who are starting treatment with an investigational medication. Dravet Syndrome and Lennox-Gastaut Syndrome are conditions that affect the brain and can cause seizures. This study looks at how the treatment affects …
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Study on Preventing Bronchopulmonary Dysplasia in Premature Infants

A
Anna Elizabeth Thomas
23 weeks - 27 weeks
All genders
Phase 2
Interventional
This study investigates bronchopulmonary dysplasia in extremely premature infants. Bronchopulmonary dysplasia is a serious lung condition that affects infants, particularly those born prematurely, causing breathing problems. The purpose of this study is to determine if an investigational medication can prevent this condition when compared to standard neonatal care.Participants in the …
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Studying Heart Health and Knowledge in Men with Prostate Cancer

S
Suparna C. Clasen, MD, MSCE
J
Jordan Holmes
18 years - 100 years
Male
This study investigates cardiovascular health literacy and risk among men with prostate cancer. The purpose is to compare these factors between African American and White men who are receiving or have completed androgen deprivation therapy, which is a treatment that reduces male hormones to slow cancer growth. The study also …
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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

S
Sandeep Batra, MD
1 month - 21 years
All genders
Phase 3
Interventional
What is the purpose of this study?Rhabdomyosarcoma is a type of cancer that occurs in the soft tissues in the body. This phaseutcomes in patients with very low risk rhabdomyosarcoma (VLR-RMS) while decreasing the burden of therapy using treatment with 24 weeks of vincristined dactinomycin (VA) and examines the use …
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Investigating Levocarnitine for Reducing Liver Issues in Leukemia Treatment

R
Rachael Schulte
15 years - 40 years
All genders
This study investigates whether adding levocarnitine to chemotherapy regimens can reduce liver problems, specifically conjugated hyperbilirubinemia, in adolescents and young adults with Acute Lymphoblastic Leukemia (ALL). Conjugated hyperbilirubinemia is a condition where there is too much bilirubin, a substance made during the breakdown of red blood cells, in the blood. …
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Ovarian Tissue Cryopreservation for Fertility Preservation in Pre and Post-Pubertal Children, Adolescents and Adults Facing a Fertility Threatening Diagnosis or Treatment Regimen

A
Amanda J. Saraf, DO
17 years or below
Female
What is the purpose of this study?Define and follow-up with the patients that undergo OTC for fertility preservation.Optimize techniques and quality assurance measures for freezing and thawing of ovarian tissue or gametesEstablish techniques for in vitro follicle maturation (IFM) or in vitro maturation of cumulus oocyte complexesInvestigate factors affecting successful …
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In Vitro Expansion and Gene Transfer Using Peripheral Blood Stem Cells

S
Scott Goebel, MD
40 years or below
Accepts healthy volunteer
All genders
The purpose of this study is to determine whether the quantity of peripheral blood stem cells can be made greater in the laboratory. Healthy male and female volunteer donors between the ages of 18-40 years will be used as a source of normal peripheral blood hematopoietic stem cells (HSC). Health …
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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Program toEvaluate the Efficacy and Safety of Tulisokibart in Participants with Moderately to SeverelyActive Crohn's Disease

M
Monika Fischer, MD
16 years - 75 years
All genders
Phase 3
Interventional
What is the purpose of this study?The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. The protocol consists of 2 studies. Study 1 includes induction and maintenance treatment, and Study 2 includes only induction treatment. Each study …
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