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Found 684 results for in-health

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Prevalence and Predictors of Hepatic Steatosis in Persons Living With HIV

N
Naga Chalasani, MD
18 years - 80 years
All genders
Observational
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver conditions associated withumulation that ranges from benign, non-progressive liver fat accumulation to severever injury, cirrhosis, and liver failure. NAFLD is the most common liver disease in USdults and the second leading cause for liver transplantation in the US. The natural …

A Phase 2A, 2-Part, Open-Label, Non-Randomized, Multicenter, Single and Multiple DoseTrial to Evaluate Pharmacokinetics, Safety and Tolerability of Aztreonam and Avibactam ±Metronidazole in Neonates and Infants From Birth to Less Than 9 Months of Age WithSuspected or Confirmed Infections Due to Gram-Negative Pathogens Requiring IntravenousAntibiotic Treatment

A
Anna Elizabeth Thomas
All genders
Phase 1/2
Interventional
The purpose of this study is to learn about the safety and effects of ATM-AVI for the possible treatment of infections caused by a type of bacteria called gram-negative bacteria.The study medicine is a combination of an antibiotic, aztreonam (ATM), and another medicine, avibactam (AVI), which is used to help …

Multicenter Randomized Controlled Trial Comparing Early Internal Fixation Versus NonOperative Care with Early Rehabilitation for LC1 Fragility Fractures of the Pelvis: a Pilot Study

Y
Yohan Jang
60 years - 100 years
All genders
Interventional
The overall goal of this research is to determine if early surgical treatment is more effective than nonoperative care and early rehabilitation at lowering the risk of complications in patients with pelvis fractures. Adult patients ages 60 years or older with a low-energy lateral compression type 1 (LC1) pelvis fracture …

Comparative Analysis of Extracellular Vesicles in Polycystic Ovary Syndrome (PCOS), Congenital Adrenal Hyperplasia (CAH), and Premature Adrenarche (PA)

E
Erica Eugster, MD
M
Manahil Mustafa
3 years - 18 years
Female
Observational
What is the purpose of this study?Extracellular vesicles (EVs) are double-membrane particles that transport proteins, microRNAs (miRNAs), and lipids, playing a crucial role in cell-to-cell communication and reflecting the cellular environment. Recent research has highlighted their potential as biomarkers and therapeutic agents in various adult conditions, yet their role in …

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of Resmetirom for the Treatment of Metabolic Dysfunction- Associated Steatotic Liver Disease (Masld) in People Living With Human Immunodeficiency Virus (Hiv)

S
Samer Gawrieh, MD
18 years - 100 years
All genders
Interventional
The purpose of this research study is to test the safety and effectiveness of the study drug, resmetirom, in participants with MASLD and HIV. This is a research study to test a drug that is already on the market with a population that was not included in the original clinical …

Comparison of Two Group Wellness Interventions for Individuals with Neurologic Conditions and Their Support Persons: A Randomized Clinical Trial

D
Devan Parrott
All genders
Interventional
The goal of this study is to examine efficacy of the treatment in individuals with chronic mild TBI and their caregivers and to determine whether patient neurobehavioral functioning moderates the relationship between treatment outcomes and burden in caregivers.  Beyond injury-based cohorts, we sought to examine whether WeCAN would be efficacious …

Biological Sample Collection for Glaucoma Research

W
Weiming Mao
18 years - 100 years
All genders
Observational
The purpose of this study is to help scientists to study glaucoma.

Natriuretic Peptides for Low Volume Platforms Enrollment Study Protocol

N
Nicholas Harrison
22 years - 100 years
All genders
Observational
The purpose of this study protocol is to collect blood samples and relevant medical data from the intended use population presenting with a clinical suspicion of acute heart failure (i.e. new-onset heart failure or worsening symptoms suggestive of decompensated or exacerbated heart failure).  Blood samples are collected to support assay …

A study of Hematopoietic Stem Cell Transplantation (HSCT) in Non-Malignant Disease using a Reduced-Intensity preparatory regime with Campath-1H Fludarabine and Melphalan

J
Jodi Skiles
All genders
The hypothesis for this study is that a preparative regimen that maximizes host immunosuppression without myeloablation will be well tolerated and sufficient for engraftment of donor hematopoietic cells. It is also to determine major toxicities from these conditioning regimens, within the first 100 days after transplantation.  The overall purpose of …

A multicenter safety study of unlicensed investigational cryopreserved cord blood units (CBUs) manufactured by the National Cord Blood Program (NCBP) and provided for unrelated hematopoietic stem cell transplantation of pediatric and adult patients

J
Jodi Skiles
All genders
The purpose of this study is to evaluate the safety of administration of the investigational cord blood units by carefully documenting all infusion-related problems. THIS STUDY IS ENROLLING BY INVITATION ONLY - The study will enroll an unlimited number of transplant recipients at participating US transplant centers (up to 10 at …
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