A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the effects of continuing pembrolizumab treatment versus observation in patients with early-stage triple-negative breast cancer (TNBC) who have achieved a pathologic complete response (pCR) after receiving chemotherapy and pembrolizumab before surgery. Triple-negative breast cancer is a type of cancer that lacks three common receptors known to fuel …
This is an observational prospective study and a retrospective study. For the prospective study, the clinical data and blood sample will be collected in accordance with standard procedure currently used in patient care at our institutions. For the retrospective study, patients requiring acute dialysis in the pediatric ICU and CVICU …
What is the purpose of this study?To establish the recommended phase II dose of a flavored preparation of orally administered irinotecan (VAL-413) when given in combination with temozolomide for five consecutive days. To characterize and compare the pharmacokinetic profiles of VAL-413 and conventional irinotecan given orally To evaluate the palatability …
This proposal will expand on our current work with the SRC/IRB approved project (IRB: #15991 Assessing Household Material Hardship in Children with Central Nervous System (CNS) Tumors). This new population can serve as a comparison, with children admitted to the hospital for infectious diseases and requiring long hospital stays and/or …
This protocol describes the epidemiology, international controversy and current state of knowledge regarding long-term maternal outcomes among women with mild CHTN who received antihypertensive therapy in pregnancy or who had preeclampsia. This document is considered a written agreement between participating investigators and their corresponding centers. Changes to the protocol during …
In this prospective and longitudinal natural history study, the aim is to identify variables that affect long-term outcomes following potentially life-saving Definitive Therapy (DT), which includes either 1) allogeneic hematopoietic cell transplant (HCT), or 2) autologous gene therapy (GT).
What is the purpose of this study?Engage with children via formal interview who received a diagnosis of cancer, and who have had a formal Oncofertility consult to understand the experience and perceptions related to both family-centered and provider-focused fertility conversations, as well as improvements Oncofertility team could make that affects …
This study investigates a device designed to monitor pressure inside the skull of neonates and infants who are at risk of developing hydrocephalus, which is a condition where there is a build-up of fluid and pressure in the brain. The device measures changes in the anterior fontanelle, also known as …
Measure the levels of key metabolites in maternal blood during pregnancies where the children developed ASD or were typically-developing (TD). If successful, this study will result in a diagnostic test for risk of having a child with ASD, and suggest treatments during pregnancy such as folate, vitamin B12, and carnitine …
What is the purpose of this study?This is a multicenter, prospective, observational Phase 4 study in the United States. The study is designed to collect both medical history and prospective data on Duchenne muscular dystrophy (DMD) treatment outcomes in participants receiving delandistrogene moxeparvovec as part of clinical care, compared to …
