A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Determine differences in international practice patterns of neonatal and infant continuous kidney replacement therapy prescriptions and the relationship between dose and major adverse kidney events
Objectives: To 1) determine performance characteristics of ultrasound (US), magnetic resonance imaging (MRI) and genetic testing (GT) in the prenatal diagnosis of aqueductal stenosis; 2) determine the gestational age that the diagnosis can be accurately made, and 3) to determine pediatric outcomes at 2 years in a contemporarily managed cohort …
The purpose of this study is to build a RedCap database to keep a retrospective and prospective log and data of the patients treated with Focused Ultrasound (FUS) Thalamotomy and Pallidotomy which will be provided clinically. The data in the RedCap database will be used for the analysis of the …
What is this study about?The purpose of this study is to test a device designed to monitor pressure within the skull of neonates and infants at risk of developing hydrocephalus (fluid and pressure build-up in the brain). The device will measure changes in the anterior fontanelle (soft spot). The study …
What is this study about?Coarctation of the aorta (CoA) tissues contain distinctive cell populations, and comprehensive analysis of these cells will provide understanding of cell abnormalities that are driving CoA. We want to define these types of cells that are abnormally located in the diseased aortic tissues of neonates with …
Measure the levels of key metabolites in maternal blood during pregnancies where the children developed ASD or were typically-developing (TD). If successful, this study will result in a diagnostic test for risk of having a child with ASD, and suggest treatments during pregnancy such as folate, vitamin B12, and carnitine …
What is the purpose of this study? This phase II trial tests the safety and best dose of revumenib when given together with chemotherapy, and how well the treatment regimen works for infants and young children with leukemia that has come back (relapsed) or does not respond to treatment (refractory) and …
What is the purpose of this study?Since its launch in 2004, the overarching aim of the Alzheimer's Disease Neuroimaging Initiative (ADNI) Study has been to validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI4 continues the previously funded ADNI1, ADNI-GO, ADNI2, and ADNI3 studies that have combined public/private collaborations between …
Placental chorangioma is a rare pregnancy complication but with significant maternal and fetal consequences. Chorangioma is a benign tumor of the placenta. As it grows, it can cause pregnancy complications. Little is known about the natural history of placental chorangioma or its response to in-utero intervention. The aim of this …
What is this study about?This study will determine whether adjuvant chemotherapy (ACT) added to ovarian function suppression (OFS) plus endocrine therapy (ET) is superior to OFS plus ET in improving invasive breast cancer-free survival (IBCFS) among premenopausal, early- stage breast cancer (EBC) patients with estrogen receptor (ER)-positive, HER2-negative tumors and …