A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The aim of our study is 1) to analyze the level of senescence markers in periodontally healthy and diseased gingival tissue;2) to analyze the level of senescence markers in periodontal and periimplant diseased gingival tissues and reveal the association between cellular senescence or ageing on progression of periodontal disease and …
Investigate the various barriers that affect adherence to the Ponseti method for clubfoot treatment in the state of IndianaTo assess the impact of these barriers on the rate of missed or discontinued clinic visits within the first three months of treatment
This is an observational prospective study and a retrospective study. For the prospective study, the clinical data and blood sample will be collected in accordance with standard procedure currently used in patient care at our institutions. For the retrospective study, patients requiring acute dialysis in the pediatric ICU and CVICU …
What is the purpose of this study?To establish the recommended phase II dose of a flavored preparation of orally administered irinotecan (VAL-413) when given in combination with temozolomide for five consecutive days. To characterize and compare the pharmacokinetic profiles of VAL-413 and conventional irinotecan given orally To evaluate the palatability …
This proposal will expand on our current work with the SRC/IRB approved project (IRB: #15991 Assessing Household Material Hardship in Children with Central Nervous System (CNS) Tumors). This new population can serve as a comparison, with children admitted to the hospital for infectious diseases and requiring long hospital stays and/or …
The purpose of this study is to test the hypothesis that skin sympathetic nerve activity (SKNA) can be used as a biomarker for physiological events including predicting neurological recovery during therapeutic hypothermia for cardiac arrest, and to risk stratify patients for recurrence of atrial fibrillation (AF) following catheter ablation.
This protocol describes the epidemiology, international controversy and current state of knowledge regarding long-term maternal outcomes among women with mild CHTN who received antihypertensive therapy in pregnancy or who had preeclampsia. This document is considered a written agreement between participating investigators and their corresponding centers. Changes to the protocol during …
In this prospective and longitudinal natural history study, the aim is to identify variables that affect long-term outcomes following potentially life-saving Definitive Therapy (DT), which includes either 1) allogeneic hematopoietic cell transplant (HCT), or 2) autologous gene therapy (GT).
We seek to determine what ratio mitigates ongoing blood loss and thus transfusion need. Because the need for whole blood transfusion is not common across most trauma centers, we seek to perform a multicenter, prospective, observational study in order to enroll a sufficient number of patients to answer this question …
The goal of this study is to use a new immune monitoring (test and define properties of the patient’s cells). This information will help work towards :in vitro panel kit, that analyzes properties like 65 cytokines, chemokines, growth factors/regulators, and soluble receptors simultaneously within 1) the GCF(gingival crevicular fluid) of …