Found 684 results for in-health
A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
H
Heba Ismail
Obesity prevalence in persons with T1D has increased, which further complicates managementd risk for complications. The proposed study is relevant to public health because it helps us understand the role of the gut microbiome in disease pathophysiology in T1D youth withbesity as well as potential mechanisms to modify disease.
Sinonasal Therapies and Histologic Correlations for Patients with Cystic Fibrosis in the Era of Highly Effective Modulator therapy
E
Elisa Illing
Establish a protocol for de-escalation of sinonasal therapies for patients on cystic fibrosis transmembrane regulator (CFTR) modulator therapies in a multidisciplinary fashion that includes a Rhinology perspective. Test the hypothesis that patients with cystic fibrosis on CFTR modulator therapy with refractory sinus disease exhibit continued tissue neutrophilic inflammation. THIS STUDY IS …
PSMA-PET to Guide Prostatectomy: A Sub-study
C
Clinton Bahler, MD
This sub-study consists of a single treatment group of men that require a PET scan to guide their radical prostatectomy, every subject will receive an MRI and the PSMA (prostate specific membrane antigen) PET scan prior to their surgery to determine if the PSMA PET scan is helpful in detecting …
AS Registry
D
David Streitman, MD
Objectives: To 1) determine performance characteristics of ultrasound (US), magnetic resonance imaging (MRI) and genetic testing (GT) in the prenatal diagnosis of aqueductal stenosis; 2) determine the gestational age that the diagnosis can be accurately made, and 3) to determine pediatric outcomes at 2 years in a contemporarily managed cohort …
Identification of Serum and Urine Biomarkers of Type 1 Diabetes
C
Carmella Evans-Molina, MD
What is the purpose of this study?The purpose of this study is to identify biomarkers (small molecules in the blood) that can predict those people at risk of developing Type 1 diabetes. THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential participants will be recruited in various ways for different aims …
Promoting Shared Decision Making in Periviable Care
B
Brownsyne Tucker Edmonds
The purpose of this study is to test the Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) among pregnant women (and their significant others) who are hospitalized for a potential periviable (early premature) delivery. We will evaluate the Periviable GOALS decision Support Tool's effects on shared …
The Rare Brain Tumour Consortium Registry and Biobank
S
Scott Coven
What is the purpose of this study?The Biobank being created by this study is located at the Hospital for Sick Children in Toronto, Canada and is a research registry that collects biological samples and medical information from individuals in participating centers around the world. The purpose of this registry is …
Creation of specimen biorepository and analysis of transcriptome and metabolome as potential mechanism in intestinal failure associated liver disease in neonate
K
Katie Huff
We will build a biorepository of blood and urine samples correlated with clinical data in neonates receiving parenteral nutrition in order to study IFALD
AIHA Patient Registry
C
Craig Lammert, MD
WHY IS THIS STUDY BEING DONE?Autoimmune hepatitis (AIH) is liver inflammation that occurs when the body’s immune system attacks liver cells. It is caused by an overactive immune system, and it is unknown why this happens. The Autoimmune Hepatitis Association (AIHA) is a not-for-profit organization seeking to develop a patient …
Safety and Efficacy of Endovascular Treatment ofIntracranial Aneurysms with Surpass Elite with GUARDian Flow Diverter(GUARD)
B
Bradley N. Bohnstedt, MD
The objective of the Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms with Surpass Elite with GUARDian Flow Diverter (GUARD) trial is to evaluate the safety and efficacy of the Surpass EliteTM with Guardian Flow Diverter System (FDS) in the treatment of unruptured, wide-neck saccular or fusiform, intracranial aneurysms …
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