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Found 701 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A PHASE III TRIAL OF THE IMPACT OF SENTINEL LYMPH NODE MAPPING ON PATIENT REPORTED LOWER EXTREMITY LIMB DYSFUNCTION IN ENDOMETRIAL CANCER

L
Lisa Landrum, MD, PhD, MS
18 years - 100 years
Female
Phase 3
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy …
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Pilot Study of a Rapid Triadic Communication Intention Elicitation Intervention (PRECursOr) to Improve Supportive Oncology Care Delivery for Patients with Advanced, Incurable Cancer and their Caregivers

K
Kristin Levoy
18 years - 100 years
Female
What is this study about?The purpose of this study is to help test an idea designed to foster more supportive talk between providers (doctors or nurse practitioners), patients, and caregivers during an outpatient oncology appointment. A caregiver is the person the patient identifies is primarily involved in their healthcare. This …
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Palliative Care Approaches for Acute Myeloid Leukemia

L
Larry Cripe, MD
18 years - 100 years
All genders
This study investigates the impact of different palliative care strategies on patients with acute myeloid leukemia (AML). Acute myeloid leukemia is a type of cancer that affects the blood and bone marrow. It is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow …
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Study of Biomarkers in Hypermobile Ehlers-Danlos Syndrome (a connective tissue disorder)

C
Clair Francomano
J
J Thomas Callaghan
18 years - 100 years
All genders
This study investigates hypermobile Ehlers-Danlos syndrome (hEDS), a condition affecting the body's connective tissues, by evaluating specific markers in the blood called biomarkers. The purpose is to find new ways to diagnose hEDS without waiting for symptoms to worsen. This involves looking at how certain cells in the body, called …
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Investigating a Special Type of Immune Cell Therapy for Acute Myeloid Leukemia (AML)

H
Huda Salman
12 years - 100 years
All genders
This study investigates a treatment for patients with a type of cancer called Acute Myeloid Leukemia (AML). AML is a cancer of the blood and bone marrow that affects white blood cells. This study focuses on patients whose AML has come back or has not responded to previous treatments. The …
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Research Study on Safety and Effects of an Investigational Medication for Advanced Solid Tumors

M
Mateusz Opyrchal, MD, PhD
18 years - 100 years
All genders
Phase 1/2
This study investigates the safety and effects of an investigational medication in people with advanced solid tumors. Advanced solid tumors are cancers that have spread and do not respond well to regular treatments. The purpose of this study is to find out how safe the medication is, how the body …
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Organoid Model Predictive of Response to Immunotherapies

M
Mateusz Opyrchal, MD, PhD
18 years or above
All genders
Observational
What is the purpose of this study?The purpose of this study is to create models out of tissue samples and treat those models with the same immunotherapy treatment the patient will be receiving, in order to validatehis process and to predict responses to therapies and use it to choose the …
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Analysis of Senescent Markers in Periodontal and Periimplant Tissue

C
Chandni Batra
18 years - 100 years
All genders
The aim of our study is 1) to analyze the level of senescence markers in periodontally healthy and diseased gingival tissue;2) to analyze the level of senescence markers in periodontal and periimplant diseased gingival tissues and reveal the association between cellular senescence or ageing on progression of periodontal disease and …
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Immunoassay of Gingival and Peri-implant Crevicular Fluid

A
Alexandru Movila, PhD
18 years - 100 years
All genders
The goal of this study is to use a new immune monitoring (test and define properties of the patient’s cells). This information will help work towards :in vitro panel kit, that analyzes properties like 65 cytokines, chemokines, growth factors/regulators, and soluble receptors simultaneously within 1) the GCF(gingival crevicular fluid) of …
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Investigating the Effectiveness of Immunotherapy in Recurrent Endometrial Cancer

L
Lisa Landrum, MD, PhD, MS
18 years - 100 years
Female
Phase 2
This study investigates the effectiveness of using a combination of investigational medications, nivolumab and ipilimumab, compared to nivolumab alone in treating patients with recurrent endometrial cancer. Endometrial cancer is a type of cancer that begins in the lining of the uterus. This study focuses on a specific type of endometrial …
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