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Found 579 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

DESIGNATE: A T cell phenotype signature driven dose finding study with siplizumab in type 1 diabetes mellitus

L
Linda DiMeglio, MD
8 years - 45 years
All genders
Researchers are looking for volunteers between 8-45 years of age who have been recently diagnosed with Type 1 diabetes mellitus (T1DM)ke part in a study identify a safe, metabolically favorable, dosing regimen of a treatment called siplizumab that targets the immune response and missing beta cell function that leads to …
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CI-NEW: Collaborative Research: HomeSHARE-Home-based Smart Health Applications across Research Environments

K
Katherine Connelly
65 years - 100 years
All genders
The purpose of this study is to understand how technologies may help older adults living on their own.
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Biospecimens of Patients with Cholestatic Liver Disease

C
Craig Lammert, MD
18 years - 85 years
All genders
Observational
The purpose of this study is to create a resource of biospecimens (bodily fluids/samples) from people with Primary Sclerosing Cholangitis (PSC) and to use these samples for current and future research relating to PSC.
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MRI Placental Changes in Prenatally Diagnosed Intrauterine Growth Restriction

B
Brandon Brown, MD
18 years - 100 years
Female
Observational
The purpose of this study is to better understand intrauterine growth restriction (IUGR), which is a common diagnosis during pregnancy.
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Potential Chronic Brain Health Effects of Concussion

T
Thomas McAllister, MD
18 years - 100 years
All genders
The purpose of this study is to learn more about the effects of concussion and/or head impact exposure among former military service academy cadets/midshipmen and NCAA student athletes who are up to 10 years out of graduation from their respective institution.
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Effects of Varied Turnout and Environmental Conditions on Balance Measures in Collegiate Ballet Dancers

C
Carrie Docherty
18 years - 25 years
All genders
The first purpose of this study is to determine how utilizing a higher degree of turnout affects a dancer?s balance. The second purpose is to determine how a dancer?s balance is affected by the varied lighting and space conditions encountered in typical training and performance.
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The Role of Sural Nerve Reflex During Jump Landing in Subjects with and without Chronic Ankle Instability

L
Leif Madsen
18 years - 30 years
All genders
Previous research has found that people who sustain an ankle sprain are much more likely to injure their ankle again in the future. Our goal with this present study is to further investigate how nerves around the ankle help the muscles in the lower leg prepare for jump landings, and …
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Early Serial Sampling of Peripheral Blood for the Purposes of Predicting Fracture Nonunion

R
Roman Natoli, MD
18 years - 60 years
All genders
The purpose of this study is to determine if certain molecules in the bloodstream can be used to improve our ability to predict the development of a nonunion or unhealed bone or fracture related infection.  This study is looking at many molecules and we will determine if the levels of …
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The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

H
Heba Ismail
11 years - 18 years
All genders
Phase 2
Interventional
Obesity prevalence in persons with T1D has increased, which further complicates managementd risk for complications. The proposed study is relevant to public health because it helps us understand the role of the gut microbiome in disease pathophysiology in T1D youth withbesity as well as potential mechanisms to modify disease.
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TrialNet Pathway to Prevention of T1D

L
Linda DiMeglio, MD
30 months - 45 years
Accepts healthy volunteer
All genders
RationaleThe accrual of data from the laboratory and from epidemiologic and prevention trials hasved the understanding of the etiology and pathogenesis of type 1 diabetes mellitus (T1DM). Genetic and immunologic factors play a key role in the development of T1DM, andharacterization of the early metabolic abnormalities in T1DM is steadily …
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