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Found 710 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

NF119: A Phase 2, Open-Label, Single Arm, Non-Controlled, Single-Stage Study to Evaluate the Safety and Effects of HLX-1502 in Patients with Plexiform Neurofibroma and Neurofibromatosis Type 1

S
Steven Rhodes
16 years or above
All genders
Phase 2
What is the purpose of this study?The trial will be an open label, single arm, phase 2 study in 20 participants. The study will assess the tolerability and efficacy of HLX-1502 in participants with NF1 16 years of age or older with progressive and/or symptomatic PN. THIS STUDY IS ENROLLING BY …
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Study on Investigational Medication for Candidemia and Invasive Candidiasis

N
Nicolas Barros, MD
18 years - 100 years
All genders
Phase 3
Interventional
This study investigates the effects and safety of an investigational medication for treating candidemia and invasive candidiasis, which are serious fungal infections caused by Candida species. Candidemia is a bloodstream infection, while invasive candidiasis occurs when the infection spreads beyond the bloodstream to other parts of the body.Participants will receive …
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Study on Low-Dose Investigational Medication for Early-Stage Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 3
This study investigates the use of low-dose tamoxifen compared to usual hormonal therapy in treating post-menopausal women with hormone-positive, HER2 negative early-stage breast cancer. Hormone-positive breast cancer is a type of cancer that grows in response to hormones like estrogen. HER2 negative means the cancer does not have higher levels …
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Studying Ways to Find Primary Ciliary Dyskinesia

E
Evans Machogu, MD
100 years or below
All genders
The purpose of this study is to investigate diagnostic methods for a condition called Primary Ciliary Dyskinesia (PCD). PCD is a genetic condition where tiny hair-like structures in the airways, called cilia, do not work properly. This can lead to infections in the lungs and other areas because the body …
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Congenital Heart Surgeons' Society (CHSS) Studies in Congenital Heart Disease

M
Mark Turrentine, MD
All genders
What is the purpose of this study?The purpose of this study is to participate in a registry of patients with congenital heart disease. Patient data from the United States, Canada, and South America (whose institutions of care are members of the Congenital Heart Surgeon’s Society) will be submitted to this …
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Concentration, H2O intake, Urine, Dehydration

A
Andrew Schwaderer, MD
12 years - 18 years
Accepts healthy volunteer
All genders
What is the purpose of this study?The purpose of this study is to determine if urine color can be used to determine urine concentration and hydration status. We will test methodology that can be easily performed by families to monitor hydration status which is an important health consideration. Our primary …
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Investigating Kidney Function Recovery in Patients Undergoing Both Liver and Kidney Transplants

M
Muhammad Jan
18 years - 100 years
All genders
This study investigates how kidney function recovers after a person receives both a liver and a kidney transplant. The purpose of this study is to see if having a liver transplant alone can improve kidney function enough that a kidney transplant might not be needed. This study is for people …
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Study of Biomarkers for Personalized Patient Management

J
Jonathan L. Berkowitz, MD, PhD
18 years - 100 years
All genders
This study investigates the use of biomarkers to help diagnose and manage patients in a personalized way. Biomarkers are substances in the body that can indicate a disease. This study looks at changes in DNA and RNA, which are molecules that carry genetic information, to find new ways to identify …
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Food Insecurity and Neonatal Kidney Disease

M
Michelle C. Starr, MD
All genders
Children born prematurely have increased risks of chronic kidney disease (CKD) and end-stage kidney disease compared to children born full-term. The factors which contribute to this risk are unclear, and one potential factor is the impact of food insecurity and maternal malnutrition. The purpose of this project is to describe …
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MRI Assessment of Cerebrospinal Fluid Circulation after Acute Spinal Cord Injury

G
Gordon Mao
18 years - 80 years
All genders
Observational
What is this study about?This study will use MRI technology before and after surgery to study the changes in the CSF flow. This may help increase the understanding of how those changes play a role in patients’ long-term recovery. This study is being done to help increase the understanding of …
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