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Found 685 results for in-health
A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Phase 2/3, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Inebilizumab In Participants With Autoimmune Hepatitis
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Craig Lammert, MD
This is a randomized, multicenter, double-blind, phase 2/3 study to evaluate the efficacy and safety of inebilizumab in participants with active AIH who are inadequatelyresponding and/or are intolerant to SOC. The main objectives of this trial are to evaluate the safety and tolerability of inebilizumab in participants with autoimmune hepatitis …
The Effect of Transcutaneous Vagal Nerve Stimulation on the Inflammatory Response to Spine Surgery
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Cristina Barboi
The purpose of the study is to determine the feasibility postoperative vagal nerve stimulation and measure the effect on the plasma inflammatory markers on postoperative days 1-3.THIS STUDY IS ENROLLING BY INVITATION ONLY - Recruitment and eligibility screening will occur through standard clinical pathways within the Department of Neurosurgery. Spine …
Evaluation of Bone Matrix Differences in Adults and Elderly Patients
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David Stockwell
The goal of this pilot study is to evaluate remodeling of the bone matrix and cellular composition as people age. We plan to utilize 2.5-5 ml of bone autograft and 2 ml of bone marrow aspirate from patients undergoing spinal decompression and fusion surgery to compare bone matrix and bone …
Assessing Physical Activity in Pediatric Patients With Difficult to Treat Asthma
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Sam Averill
Kids and teens with asthma often get less physical activity than recommended, even though exercise can improve asthma symptoms, lung function, overall fitness, and mental health. But we don’t fully understand: • How active our own clinic’s patients actually are • What they think about exercise • What gets in the way • What …
Prospective Measurement of Normative Esophageal Distensibility Using EndoFLIP in Asymptomatic Children
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Brett Hoskins
Endoluminal functional lumen imaging probe (EndoFLIP) is a minimally invasive, novel device that aids in the diagnosis of esophageal disorders. EndoFLIP is increasingly utilized for assessing esophageal biomechanics, yet normative data for children are lacking. Due to developmental differences in compliance and luminal size, adult reference values are not generalizable …
Newborn Screen for Severe Combined Immunodeficiency (SCID) Database/Registry
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Jay Jin
The purpose of this project is to collect and analyze relevant clinical data from children who have been identified as having a positive newborn screen for severe combined immunodeficiency (SCID) in order to understand the most common causes of SCID in Indiana, identify important immune parameters, determine the safest prophylactic …
Total Cancer Care: A Lifetime Partnership with Patients Who Have or May be at Risk of Having Cancer
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Anna Maria Storniolo, MD
The purpose of this research study is to collect and store biospecimens and personal health information to use in future research studies. The Total Cancer Care Program (TCCP) establishes a unique collection of blood, tissue, other biological samples and their associated data (survey data, medical records data, cancer registry data, …
Diabetes RElated to Acute pancreatitis and its Mechanisms (DREAM)
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Evan Fogel, MD
Researchers at Indiana University School of Medicine are conducting a study to find out how many people with acute pancreatitis develop diabetes. Diabetes is a known complication of acute pancreatitis. For some people, diabetes can last a few weeks after acute pancreatitis, but for others, it can appear a year or …
Testicular Tissue Cryopreservation for Fertility Preservation
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Amanda J. Saraf, DO
What is the purpose of this study?Testicular tissue cryopreservation is an experimental procedure where a young boy's testicular tissue is retrieved and frozen. This technique is reserved for young male patients who are not yet producing mature sperm, with the ultimate goal that their tissue may be used in the …
Crohn's Disease: Pharmacokinetics, Efficacy, and Safety of Risankizumab in Pediatric Subjects with Moderately to Severely Active Crohn's Disease
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Tina Zhang
The objective of this study is to assess the pharmacokinetics (PK), efficacy, and safety of risankizumab in pediatric subjects with moderately to severely active CD aged 2 to biologic therapies. THIS STUDY IS ENROLLING BY INVITATION ONLY
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