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Found 682 results for in-health

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Assessing Physical Activity in Pediatric Patients With Difficult to Treat Asthma

S
Sam Averill
12 years - 18 years
All genders
Observational
Kids and teens with asthma often get less physical activity than recommended, even though exercise can improve asthma symptoms, lung function, overall fitness, and mental health. But we don’t fully understand: • How active our own clinic’s patients actually are • What they think about exercise • What gets in the way • What …

Prospective Measurement of Normative Esophageal Distensibility Using EndoFLIP in Asymptomatic Children

B
Brett Hoskins
5 years - 17 years
All genders
Interventional
Endoluminal functional lumen imaging probe (EndoFLIP) is a minimally invasive, novel device that aids in the diagnosis of esophageal disorders. EndoFLIP is increasingly utilized for assessing esophageal biomechanics, yet normative data for children are lacking. Due to developmental differences in compliance and luminal size, adult reference values are not generalizable …

Newborn Screen for Severe Combined Immunodeficiency (SCID) Database/Registry

J
Jay Jin
All genders
Observational
The purpose of this project is to collect and analyze relevant clinical data from children who have been identified as having a positive newborn screen for severe combined immunodeficiency (SCID) in order to understand the most common causes of SCID in Indiana, identify important immune parameters, determine the safest prophylactic …

Total Cancer Care: A Lifetime Partnership with Patients Who Have or May be at Risk of Having Cancer

A
Anna Maria Storniolo, MD
18 years - 100 years
All genders
The purpose of this research study is to collect and store biospecimens and personal health information to use in future research studies. The Total Cancer Care Program (TCCP) establishes a unique collection of blood, tissue, other biological samples and their associated data (survey data, medical records data, cancer registry data, …

Diabetes RElated to Acute pancreatitis and its Mechanisms (DREAM)

E
Evan Fogel, MD
18 years - 75 years
All genders
Researchers at Indiana University School of Medicine are conducting a study to find out how many people with acute pancreatitis develop diabetes. Diabetes is a known complication of acute pancreatitis. For some people, diabetes can last a few weeks after acute pancreatitis, but for others, it can appear a year or …

Testicular Tissue Cryopreservation for Fertility Preservation

A
Amanda J. Saraf, DO
Male
Observational
What is the purpose of this study?Testicular tissue cryopreservation is an experimental procedure where a young boy's testicular tissue is retrieved and frozen. This technique is reserved for young male patients who are not yet producing mature sperm, with the ultimate goal that their tissue may be used in the …

Crohn's Disease: Pharmacokinetics, Efficacy, and Safety of Risankizumab in Pediatric Subjects with Moderately to Severely Active Crohn's Disease

T
Tina Zhang
16 years - 80 years
All genders
Interventional
The objective of this study is to assess the pharmacokinetics (PK), efficacy, and safety of risankizumab in pediatric subjects with moderately to severely active CD aged 2 to biologic therapies. THIS STUDY IS ENROLLING BY INVITATION ONLY

Improving sleep in acute respiratory failure survivors

B
Babar Khan, MD
18 years - 100 years
All genders
The purpose of this study is to evaluate the impact of a sleep deprivation and disruption on quality of life of acute respiratory failure ICU survivors using sleep actigraphy. Sleep actigraphy is a method of measuring sleep parameters and average motor activity over a period of days to weeks using …

A Randomized, Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL Pre-filled Syringe With 1 mL Pre-filled Syringe in Adult Participants With Autoimmune Disease

D
Domenick Zero, DDS, MS
18 years - 70 years
All genders
Phase 2
Interventional
What is the purpose of this study?The purpose of this study is to demonstrate the comparability of ianalumab exposure following the sub-cutaneous (s.c.) administration of one injection of 300 mg/2 mL auto-injector (AI) versus two injections of 150 mg/1 mL pre-filled syringe (PFS), and to evaluate the safety and tolerability …

A 52-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Group Sequential Study to Evaluate the Efficacy and Safety of Rilzabrutinib in Patients Aged 10 to 65 Years With Sickle-Cell Disease (Libra)

S
Seethal Jacob, MD
10 years - 65 years
All genders
Interventional
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, group-sequential study (Part A), followed by an open-label LTE period (Part B) to investigate the efficacy, and safety of rilzabrutinib in participants with sickle-cell disease (SCD).THIS STUDY IS ENROLLING BY INVITATION ONLY
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