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Found 684 results for in-health

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Randomized, Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL Pre-filled Syringe With 1 mL Pre-filled Syringe in Adult Participants With Autoimmune Disease

D
Domenick Zero, DDS, MS
18 years - 70 years
All genders
Phase 2
Interventional
What is the purpose of this study?The purpose of this study is to demonstrate the comparability of ianalumab exposure following the sub-cutaneous (s.c.) administration of one injection of 300 mg/2 mL auto-injector (AI) versus two injections of 150 mg/1 mL pre-filled syringe (PFS), and to evaluate the safety and tolerability …

A 52-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Group Sequential Study to Evaluate the Efficacy and Safety of Rilzabrutinib in Patients Aged 10 to 65 Years With Sickle-Cell Disease (Libra)

S
Seethal Jacob, MD
10 years - 65 years
All genders
Interventional
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, group-sequential study (Part A), followed by an open-label LTE period (Part B) to investigate the efficacy, and safety of rilzabrutinib in participants with sickle-cell disease (SCD).THIS STUDY IS ENROLLING BY INVITATION ONLY

Indiana University GI Neuromuscular Pathology Prospective Registry

J
John Wo, MD
18 years - 100 years
All genders
What is the purpose of this study?The purpose of this study is to determine if ICC abnormalities of the stomach and proximal jejunum can be used as a biologic marker in predicting clinical outcome in patients undergoing surgical implantation of GES for severe gastroparesis. The primary aim is to determine …

Changes in Esophageal Distensibility with Proton Pump Inhibitors in Patients with Esophageal Eosinophilia: A Pilot Study

J
John Wo, MD
18 years - 65 years
All genders
The purpose of this study is to measure the stiffness of the esophagus before and after treatment for inflammation in the esophagus.THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential participants will be identified from the GI clinic and GI endoscopy suite procedure schedule and will be approached by research …

Diabetes Prevention Programming for Women with a History of Gestational Diabetes (Positive Outcomes for Women (POW)

T
Tamara Hannon, MD
18 years - 99 years
Female
The purpose of this study is to offer women with a history of gestational diabetes access to diabetes prevention programming; their children 10 and older can participate.THIS STUDY IS ENROLLING BY INVITATION ONLY - Women will be recruited for this study in a variety of ways, including women participants in …

Genetics of Heritable Disease (IU-GHD)

S
Stephanie Ware, MD
100 years or below
Accepts healthy volunteer
All genders
Why is this study being done?The purpose of this study is to obtain information from individuals and their families with a heritable disease in order to understand the molecular genetics of heritable disorders. THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential subjects will be identified by study staff through the …

A GLOBAL PROSPECTIVE OBSERVATIONAL REGISTRY OF PATIENTS WITH POMPE DISEASE

C
Cynthia Bodkin, MD
18 years - 100 years
All genders
Observational
What is this study about?The goal of this registry is to assess clinical outcomes in patients with Pompe disease, including patients with LOPD or IOPD, regardless of current or previous therapy. The use of real-world data for this registry will enable the evaluation of the long-term safety and effectiveness of …

PREVALENCE OF BRONCHIAL HYPERRESPONSIVENESS IN PRIMARY CILIARY DYSKINESIA

E
Evans Machogu, MD
6 years - 100 years
All genders
Phase 1
All people have tiny hairs that help move mucus through their air tubes. When these hairs do not form or do not work properly it can cause the air tubes to get clogged with mucus, which can cause PCD. The purpose of this study is to look at children with PCD …

Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB) (PPAP Spine)

S
Senthil Packiasabapathy
10 years - 17 years
All genders
Interventional
The purpose of this collaborative CTSA application is to develop an innovative perioperativegesia platform (PPAP) to improve analgesia and reduce serious immediate andg-term adverse outcomes of perioperative opioids in children undergoing painful surgery.

The Resilience Songwriting Program for Adolescent Bereavement

J
Jayme Allen, MD
12 years - 18 years
Accepts healthy volunteer
All genders
Experiencing the death of a loved one is hard.  We want to understand how a songwriting program can impact grief and resiliency in teens who have experienced the loss of aloved one. The purpose of this study is to learn more about how a songwriting program may affect grief and …
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