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Found 702 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Safety and Tolerability of Investigational Medication for Seizures Lasting Longer Than Usual

M
Marlene Bultemeher
12 years - 17 years
All genders
Interventional
This study investigates the safety and tolerability of an investigational medication for people aged 12 and older who experience prolonged seizures. Prolonged seizures are seizures that last longer than usual and can be dangerous if not treated. The investigational medication is taken by inhalation, which means breathing it in as …
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Study of Genetic Factors in Heart and Blood Vessel Diseases

L
Larry Markham
100 years or below
All genders
This study investigates the genetic causes of thoracic aortic aneurysm (TAA) and other aortic diseases. The purpose is to find new genes that may cause these conditions and understand how genetics can affect the severity of aortic and valve diseases.Participants will provide blood and urine samples. If blood samples cannot …
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Translational Breast Cancer Research Consortium Biospecimen & Outcomes Repository

K
Kathy Miller, MD
18 years - 100 years
Female
The purpose of this study is to develop a repository of clinical data and outcomes, with and without corresponding specimens from individuals who have participated in TBCRC studies.
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TArgeting Type 1 Diabetes Using POLyamines (TADPOL) (TADPOL)

E
Emily Sims, MD
6 years - 40 years
All genders
Phase 2
Interventional
The goal of this clinical trial is to test a drug known as DFMO in people with Type 1 Diabetes (T1D). The main question[s] it aims to answer are:Does it reduce stress on the cells that make insulin?Does it preserve what is left of the body's insulin production? Participants will …
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Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)

S
Scott Goebel, MD
1 month - 79 years
All genders
Phase 1/2
Interventional
What is the purpose of this study?BK cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Captureystem will be safe and effective in decreasing specific viral load in children, adolescents and young adults (CAYA) with refractory BK infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT) or with primary …
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Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

S
Scott Goebel, MD
1 month - 30 years
All genders
Phase 2
Interventional
What is the purpose of this study?CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovirus (CMV) infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid organ …
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National Liver Cancer Screening Trial (TRACER)

N
Naga Chalasani, MD
18 years - 85 years
All genders
What is this study about?The National Liver Cancer Screening Trial is an adaptive randomized phase IV Trial comparing ultrasound-based versus biomarker-based screening in 5500 patients with cirrhosis from any etiology or patients with chronic hepatitis B infection. Eligible patients will be randomized in a 1:1 fashion to Arm A using …
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Comparing treatment, costs, and patient outcomes of close-range vs long-range GSWs to the upper extremity.

E
Erin Weber
18 years - 100 years
All genders
Observational
What is this study about?The purpose of this study is to measure outcomes related to close-range and long-range gunshot wounds to the hand, wrist, and arm.   THIS STUDY IS ENROLLING BY INVITATION ONLY - Patients will be identified and recruited by Dr. Weber and other hand surgeons providing care for the …
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A Protocol for Children and Young Adults Diagnosed with a Central Nervous System (CNS) Tumor to Assess Cognitive, Quality of Life (QOL), and Comprehensive Effects of Therapies

S
Scott Coven
39 years or below
All genders
What is the purpose of this study?To longitudinally assess cognitive outcomes using an a neurocognitive screening battery in children and young adults diagnosed with a CNS tumor. To longitudinally assess the impact of specific therapies on the QOL in children and young adults diagnosed with a CNS tumor.To longitudinally assess …
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DAY101 vs. Standard of Care Chemotherapy in Pediatric Patients With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

M
Michael Ferguson, MD
25 years or below
All genders
Phase 3
Interventional
What is the purpose of this study?This is a 2-arm, randomized, open-label, multicenter, global, Phase 3 trial to evaluate the efficacy, safety, and tolerability of tovorafenib monotherapy versus standard of care (SoC) chemotherapy in patients with pediatric low-grade glioma (LGG) harboring an activating rapidly accelerated fibrosarcoma (RAF) alteration requiring front-line …
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