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Found 573 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

MINDS Imaging Ancillary Study (MINDS)

R
Rupa Radhakrishnan, MD
18 years - 30 years
All genders
Observational
This study is an ancillary study to the NHLBI-funded Pediatric Heart Network (PHN) "Multi-Institutional Neurocognitive Discovery Study" (MINDS) in Adult Congenital Heart Disease (ACHD). The MINDS-ACHD" study will recruit 500 complex CHD patients between18-30 years old. The investigators propose to quantitate multi-modal neuroimaging biomarkers (brainjury, structure and physiology) which are …
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Bevacizumab Treatment For Posterior Zone I ROP (ROP4)

K
Kathryn Haider, MD
6 months or below
All genders
Phase 2
Interventional
Type 1 retinopathy of prematurity in zone I represents the most severe type of ROP and hashe worst prognosis. It is unknown whether low-dose bevacizumab will be successful in thesevere cases. Also unknown is the timing and extent of peripheral retinal vascularizationw-dose bevacizumab compared with the standard dose. The current …
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Looped Versus Linear Ureteral Stent Self-Extraction String

M
Marcelino Rivera
18 years - 100 years
All genders
This study will assess whether having looped strings or linear strings makes a difference in how often ureteral stents are removed or dislodged by accident. 
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Serum Protein-Based Indices for the Progression of Fracture Healing and Nonunion

R
Roman Natoli, MD
18 years - 70 years
All genders
To define a serum protein-based diagnostic for the progression and failure of fracture healing, through the identification of a set of serum proteins that appear at early times of biological healing and show a specific correlation with later radiological and functional signs used to define delayed healing and non-union. 
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Liver Stiffness in Patients with Underlying Polycystic Kidney Disorders.

J
Jean Molleston, MD
3 years - 65 years
All genders
Use Fibroscan to determine thevalence of CHF in an ADPKD population and the incidence over a four-yeard in these patients. Use Fibroscan to determine thevalence of congenital hepatic fibrosis in an ARPKD population Use fibroscan to determine thevalence of fibrotic liver disease in patients with other cystic kidneydiseases such as …
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Use of eye tracking to aid in autism risk detection

R
Rebecca McNally Keehn
12 months - 48 months
All genders
Observational
What is the purpose of this study?The study will use a non-invasive remote eye-tracking system (Eyelink Portable Duo) to acquire a short series (less than 15 mins) of eye-tracking measures (e.g., look time, pupil diameter), which may be associated with autism in young children ages 12-48 months. We will recruit …
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Collaborative Study on the Genetics of Alcoholism

M
Martin Plawecki, MD, PhD
40 years - 100 years
All genders
Observational
What is the purpose of this study?The overarching aim of the COGA project is to identify and understand genetic mechanisms underlying alcohol use disorders and related disorders. The current research data collection methods represent a continuation of the COGA methodologies that have evolved over the course of the study. The …
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Ovarian Tissue Cryopreservation for Fertility Preservation in Pre and Post-Pubertal Children, Adolescents and Adults Facing a Fertility Threatening Diagnosis or Treatment Regimen

A
Amanda J. Saraf, DO
17 years or below
Female
What is the purpose of this study?Define and follow-up with the patients that undergo OTC for fertility preservation.Optimize techniques and quality assurance measures for freezing and thawing of ovarian tissue or gametesEstablish techniques for in vitro follicle maturation (IFM) or in vitro maturation of cumulus oocyte complexesInvestigate factors affecting successful …
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A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

S
Sandeep Batra, MD
12 months - 21 years
All genders
Phase 1/2
Interventional
What is the purpose of this study?This phase I/II trial tests the safety, side effects, and best dose of selinexor given in combination with standard radiation therapy in treating children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG) or high-grade glioma (HGG) with a genetic change called …
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Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

S
Sandeep Batra, MD
1 year - 21 years
All genders
Phase 1
Interventional
What is the purpose of this study?Tagraxofusp is a protein-drug conjugate consisting of a diphtheria toxin redirected to target CD123 has been approved for treatment in pediatric and adult patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN). This trial aims to examine the safety of this novel agent in pediatric …
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