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Found 705 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Safety and Feasibility Single-Arm Study of a Novel Catheter Thrombectomy Device For the Treatment of Pulmonary Embolism (ENGULF)

S
Sabah D. Butty, MD
18 years - 90 years
All genders
Interventional
What is the purpose of this study?Evaluation of initial safety and clinical feasibility of the Helo PE Thrombectomy System for thrombectomy in acute submassive pulmonary embolism (PE).PRIMARY OBJECTIVES:Composite device-related Major Adverse Event (MAE) rate, defined as any of the following events within 48 hours (+/- 24 hours) of the procedure: …
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Placenta Accreta Database

H
Hiba Mustafa, MD
18 years or above
Female
Observational
What is the purpose of this study?Placenta accreta spectrum (PAS) is a condition when the placenta grows too deeply into the uterus. Women who have had a C-section before and have a placenta that covers their cervix are at higher risk of getting PAS.  The purpose of this study is …
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Investigating Surgical Positions and Their Impact on Vision in Idiopathic Intracranial Hypertension

D
Devon Mackay
17 years or below
All genders
Interventional
This study investigates how certain surgical positions, such as Trendelenburg positioning (TP) and pneumoperitoneum (PP), might affect the optic nerve and vision in people with idiopathic intracranial hypertension (IIH). Idiopathic intracranial hypertension is a condition where the pressure around the brain increases, which can lead to optic nerve swelling known …
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Using ECG Mapping for Treating Irregular Heartbeats

M
Mithilesh Das
22 years - 100 years
All genders
Interventional
This study investigates the treatment of Atrial Fibrillation (AF), a condition where the heart beats in an irregular and often rapid manner. The purpose of this study is to compare two different methods for treating AF: using a mapping system called vMap in addition to pulmonary vein isolation (PVI), and …
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Study on Integrated Therapies for Alcohol Use Disorder and Severe Alcohol-Associated Liver Disease

R
Raj Vuppalanchi, MD
18 years - 100 years
All genders
Interventional
This study investigates the effects of combining treatments for alcohol use disorder (AUD) with therapies for severe alcohol-associated liver disease (sAH). AUD is when someone cannot control their drinking despite negative effects. sAH is a serious liver condition caused by heavy drinking. The study aims to see if these combined …
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Investigating Barriers to Emergency Department Survey Participation

D
Diane Kuhn
18 years - 39 years
All genders
Observational
This study investigates the barriers and facilitators to completing emergency department (ED) patient experience surveys among underrepresented groups. The purpose is to understand the perspectives of younger patients, Black or African-American patients, and those with Medicaid insurance on how they can provide feedback on their care.Participants will take part in …
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Study on Growth Prediction Using Fluid Between Teeth and Gums

R
Rishma Shah
7 years - 20 years
Accepts healthy volunteer
All genders
This study investigates how factors in the fluid between teeth and gums, called gingival crevicular fluid, relate to growth in orthodontic patients. The purpose is to find a non-invasive way to predict future growth by measuring growth hormone-related factors and comparing them with age, height, weight, and X-ray indicators.Participants will …
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Clinical Pharmacokinetics of Labetalol in Pregnancy

S
Sara Quinney
18 years or above
Accepts healthy volunteer
Female
What is this study about?This study will determine how plasma concentrations of labetalol, a medication commonly used to treat hypertension in pregnancy, change during and after pregnancy and how this may impact antihypertensive therapy. The study will also evaluate exposure of fetus/neonate to labetalol through cord blood and breast milk. Study …
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Investigating the Addition of an Investigational Medication to Chemotherapy for Osteosarcoma

S
Sandeep Batra, MD
40 years or below
All genders
Phase 2/3
Interventional
This study investigates the use of an investigational medication, cabozantinib, in combination with standard chemotherapy for patients with newly diagnosed osteosarcoma. Osteosarcoma is a type of bone cancer that typically affects the long bones in the body. Cabozantinib is a kinase inhibitor, which means it works by blocking specific enzymes …
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A Phase 3 Randomized, Open-label Induction, Double-blind Maintenance, Parallel-group, Multicenter Protocol to Evaluate the Efficacy, Safety, and Pharmacokinetics, of Guselkumab in Pediatric Participants with Moderately to Severely Active Ulcerative Colitis

M
Marian Pfefferkorn
2 years - 17 years
All genders
Phase 3
Interventional
What is this study about?The purpose of this study is to evaluate the efficacy of guselkumab in pediatric participants with moderately to severely active ulcerative colitis at the end of maintenance therapy among participants who were induction responders.THIS STUDY IS ENROLLING BY INVITATION ONLY
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