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Found 700 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase 3 Randomized, Open-label Induction, Double-blind Maintenance, Parallel-group, Multicenter Protocol to Evaluate the Efficacy, Safety, and Pharmacokinetics, of Guselkumab in Pediatric Participants with Moderately to Severely Active Ulcerative Colitis

M
Marian Pfefferkorn
2 years - 17 years
All genders
Phase 3
Interventional
What is this study about?The purpose of this study is to evaluate the efficacy of guselkumab in pediatric participants with moderately to severely active ulcerative colitis at the end of maintenance therapy among participants who were induction responders.THIS STUDY IS ENROLLING BY INVITATION ONLY
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Cold Snare Endoscopic Mucosal Resection of Duodenal Adenomas more than or equal to 10 mm: A prospective cohort study

J
John Guardiola
18 years - 100 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to evaluate the safety and effectiveness of Cold Snare Endoscopic Mucosal Resection (CS-EMR) for the removal of non-cancerous polyps that are located in the small bowel (duodenal) and are 10 millimeters or greater in size. The goal of this …
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A Randomized, Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL Pre-filled Syringe With 1 mL Pre-filled Syringe in Adult Participants With Autoimmune Disease

D
Domenick Zero, DDS, MS
18 years - 70 years
All genders
Phase 2
Interventional
What is the purpose of this study?The purpose of this study is to demonstrate the comparability of ianalumab exposure following the sub-cutaneous (s.c.) administration of one injection of 300 mg/2 mL auto-injector (AI) versus two injections of 150 mg/1 mL pre-filled syringe (PFS), and to evaluate the safety and tolerability …
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Aromatherapy Use to Decrease Functional Nausea and Increase Quality of Life in Pediatric Patients Seen in a Quaternary Care Outpatient Disorder of Gut Brain Interaction Clinic

E
Erik David Andrewski
9 years - 18 years
All genders
Interventional
What is the purpose of this study?The purpose of this study is to determine if an outpatient population of pediatric patients with nausea related to a disorder of gut-brain interaction (DGBI) have decreased symptoms after use of aromatherapy (QueaseEase) as measured by the Nausea ProfileTHIS STUDY IS ENROLLING BY INVITATION …
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Study on the Effectiveness of Investigational Medication Versus Standard Treatment for Glioblastoma, a Type of Brain Cancer

K
Kathryn Nevel
18 years - 100 years
All genders
Phase 3
This study investigates the effectiveness and safety of an investigational medication compared to a standard treatment in adults with newly-diagnosed glioblastoma. Glioblastoma is a type of brain cancer. The study aims to see if the investigational medication can improve the time patients live without the cancer getting worse and overall …
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Study on Timing of Surveillance Colonoscopy After Growth (Polyp) Removal

J
John Guardiola
18 years - 100 years
All genders
Interventional
This study investigates the timing of follow-up colonoscopies after the removal of nonpedunculated colorectal polyps. These are growths in the colon that do not have a stalk and are between 20 to 50 mm in size. The purpose of this study is to see if having a follow-up colonoscopy at …
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Heart Health Study After Heart Attack

R
Rolf Kreutz, MD
45 years - 100 years
All genders
Phase 3
Interventional
This study investigates cardiovascular risk in people who have recently had a heart attack, known as an acute coronary syndrome (ACS). The purpose is to understand how an investigational medication might affect heart health in individuals with a specific genetic makeup. Participants must have a certain genetic profile to take …
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Studying Esophagus Stiffness in Certain Patients

J
John Wo, MD
18 years - 65 years
All genders
This study investigates how the stiffness of the esophagus changes in patients with esophageal eosinophilia when treated with proton pump inhibitors (PPIs). Esophageal eosinophilia is a condition where there are too many eosinophils, a type of white blood cell, in the esophagus, which can cause inflammation. The purpose of this …
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Genetics of Heritable Disease (IU-GHD)

S
Stephanie Ware, MD
100 years or below
Accepts healthy volunteer
All genders
Why is this study being done?The purpose of this study is to obtain information from individuals and their families with a heritable disease in order to understand the molecular genetics of heritable disorders. THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential subjects will be identified by study staff through …
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Parkinson's Progression Markers Initiative 2.0 Remote Study

T
Tatiana Foroud
30 years - 100 years
All genders
What is the purpose of this study?The purpose of PPMI 2.0 Remote is to find out if information collected remotely (by internet, mail, home visits, or phone applications) can help identify individuals at an increased risk of developing Parkinson’s Disease.  Identifying at-risk individuals may also help researchers learn how to …
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