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Found 708 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

An open-label, phase II proof-of-concept study to evaluate the clinical efficacy and safety of tapinarof for adult patients with palmoplantar keratoderma

D
David Rosmarin
18 years - 75 years
All genders
Phase 2
Interventional
What is the purpose of this study?This study is being done to find out how safe and how well the drug Tapinarof (VTAMA) works for stopping or treating palmoplantar keratoderma, which is a condition characterized by thickened skin on your palms and soles.  Tapinarof, used as a topical 1% cream, …
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Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children

M
Michael Hobson, MD
3 days - 2 years
All genders
Interventional
What is the purpose of this study?The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory failure will be beneficial, mediated through the matrix metalloproteinase (MMP)-9 pathway. THIS STUDY IS ENROLLING BY INVITATION ONLY
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A Global Multi-Center Prospective Observational Cohort to Support Drug Development in Adult Patients with Primary Sclerosing Cholangitis

C
Craig Lammert, MD
18 years - 75 years
All genders
Observational
What is the purpose of this study?To develop an appropriate real-world data comparator cohort to support the design, execution, and serve as an external control for interventional clinical trials in PSC. This is a Global, multi-center longitudinal observational cohort study. Collection of prospective clinical data to include liver-related clinical outcomes …
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Role of neutrophil-specific NOX2 in alcohol-induced liver injury

S
Suthat Liangpunsakul, MD
18 years - 70 years
Accepts healthy volunteer
All genders
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …
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Study on Investigational Medication for Relapsing Multiple Sclerosis

A
Ajay Gupta
18 years - 55 years
All genders
Interventional
The purpose of this study is to investigate an investigational medication for people with relapsing multiple sclerosis (RMS). RMS is a condition where the immune system mistakenly attacks the protective covering of nerves, causing symptoms like fatigue, vision problems, and difficulty with coordination. This study will compare the investigational medication …
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PREVENT ALL ALS

C
Cynthia Bodkin, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?PREVENT ALL ALS is a prospective, observational cohort study enrolling individuals at risk for carrying inherited genetic variants known to be causative for ALS. This is a longitudinal observational study involving collection of clinical data, outcomes andbiofluid samples. There is also an optional sub-study …
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Investigating Music Interventions for Reducing Stress in Young Children Undergoing a Procedure to Replace Damaged Cells

S
Sheri Robb
3 years or below
All genders
This study investigates how music can help reduce stress in young children undergoing stem cell transplants and their parents. The purpose is to adapt a music-based intervention called Active Music Engagement (AME) for children under 3 years old and their parents. This adaptation aims to decrease distress and improve coping …
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Study on Safety and How Well Investigational Wound Dressing and Therapy Work

G
Greg Westin
22 years - 100 years
Accepts healthy volunteer
All genders
This study investigates the safety and effectiveness of an investigational wound dressing used with a special therapy for treating different types of wounds. The purpose is to gather information on how well the dressing and therapy work together after they have been approved for use. The study will include people …
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The Return of the Pancreas: Evaluating impact of CFTR modulators on pancreatic function

M
Molly Bozic, MD
18 years or below
All genders
Interventional
What is the purpose of this study?This study aims to see how often children with cystic fibrosis (CF) develop normal pancreatic function after starting treatment with CFTR modulators and to identify what factors might influence this change. We will also look at whether it is safe for these patients to …
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ARTEMIS - Effects of Ziltivekimab Versus Placebo on Cardiovascular Outcomes in Patients With Acute Myocardial Infarction

R
Rolf Kreutz, MD
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes.THIS STUDY IS ENROLLING BY …
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