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Found 701 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Role of neutrophil-specific NOX2 in alcohol-induced liver injury

S
Suthat Liangpunsakul, MD
18 years - 70 years
Accepts healthy volunteer
All genders
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …
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Study on Investigational Medication for Relapsing Multiple Sclerosis

A
Ajay Gupta
18 years - 55 years
All genders
Interventional
The purpose of this study is to investigate an investigational medication for people with relapsing multiple sclerosis (RMS). RMS is a condition where the immune system mistakenly attacks the protective covering of nerves, causing symptoms like fatigue, vision problems, and difficulty with coordination. This study will compare the investigational medication …
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PREVENT ALL ALS

C
Cynthia Bodkin, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?PREVENT ALL ALS is a prospective, observational cohort study enrolling individuals at risk for carrying inherited genetic variants known to be causative for ALS. This is a longitudinal observational study involving collection of clinical data, outcomes andbiofluid samples. There is also an optional sub-study …
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Investigating Music Interventions for Reducing Stress in Young Children Undergoing a Procedure to Replace Damaged Cells

S
Sheri Robb
3 years or below
All genders
This study investigates how music can help reduce stress in young children undergoing stem cell transplants and their parents. The purpose is to adapt a music-based intervention called Active Music Engagement (AME) for children under 3 years old and their parents. This adaptation aims to decrease distress and improve coping …
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Study on Safety and How Well Investigational Wound Dressing and Therapy Work

G
Greg Westin
22 years - 100 years
Accepts healthy volunteer
All genders
This study investigates the safety and effectiveness of an investigational wound dressing used with a special therapy for treating different types of wounds. The purpose is to gather information on how well the dressing and therapy work together after they have been approved for use. The study will include people …
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The Return of the Pancreas: Evaluating impact of CFTR modulators on pancreatic function

M
Molly Bozic, MD
18 years or below
All genders
Interventional
What is the purpose of this study?This study aims to see how often children with cystic fibrosis (CF) develop normal pancreatic function after starting treatment with CFTR modulators and to identify what factors might influence this change. We will also look at whether it is safe for these patients to …
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ARTEMIS - Effects of Ziltivekimab Versus Placebo on Cardiovascular Outcomes in Patients With Acute Myocardial Infarction

R
Rolf Kreutz, MD
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes.THIS STUDY IS ENROLLING BY …
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Study on Investigational Medication for CIDP

C
Cynthia Bodkin, MD
18 years - 75 years
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication compared to a placebo in adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). CIDP is a condition where the body's immune system attacks the protective covering of the nerves, leading to weakness and numbness. The study aims to understand how well the …
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Study of an Investigational Medication in Relapsing Multiple Sclerosis

A
Ajay Gupta
18 years - 55 years
All genders
Phase 3
Interventional
The purpose of this study is to compare the effectiveness and safety of an investigational medication to an existing treatment in adults with relapsing forms of multiple sclerosis (MS). Multiple sclerosis is a condition where the immune system mistakenly attacks the protective covering of nerves, leading to communication problems between …
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Cervical Myelopathy in Hip Fracture Patients.

F
Flynn Rowan
50 years - 100 years
All genders
Interventional
What is the purpose of this study?Recent evidence has demonstrated a high rate of undiagnosed cervical myelopathy in patients presenting with hip fractures from a ground level fall. Identification and treatment of cervical myelopathy can help prevent falls and future fragility fractures. The purpose of this study is to screen …
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