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Found 697 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Neoadjuvant pembrolizumab in patients with muscle-invasive bladder cancer with selective bladder sparing

J
Jennifer King
18 years or above
All genders
Phase 2
Interventional
What is the purpose of this study?Subjects with cT2-T3N0M0 urothelial cancer of the bladder will be enrolled. After completingwo cycles of pembrolizumab, subjects will undergo a restaging MRI of the abdomen and pelvis with a standard acquisition protocol (as outlined in the protocol) as well as CT chest. A CThe …
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Brief Interventions for Adolescent Alcohol Use

Z
Zachary Adams
12 years - 17 years
All genders
Interventional
This study investigates the effects of brief interventions on adolescents with mild alcohol use disorder (AUD). The purpose is to understand how different treatment approaches can help reduce alcohol use among youth. Adolescents aged 12-17, along with their caregivers, will be randomly assigned to one of three study arms: a …
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Online study

Study on Medication for Children's Growth Conditions

J
John Fuqua, MD
3 years - 11 years
All genders
Phase 2
Interventional
This study investigates the effects of an investigational medication on children with Noonan syndrome, Turner syndrome, and SHOX deficiency who have not grown adequately during or after treatment with human growth hormone. The purpose of this study is to evaluate how three different doses of the investigational medication affect growth …
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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

S
Sherif Farag, MD
All genders
Observational
This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and otherdications.
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A Prospective, Multi-Center, Open-Label Clinical Investigation and Longitudinal Registry of the Cleaner Vac® Thrombectomy System for Peripheral Venous Thrombus Removal, Including a Subgroup Analysis of Patients With Lower Extremity Proximal Deep Vein Thrombosis

S
Sabah D. Butty, MD
18 years - 100 years
All genders
Observational
The primary objective of this clinical investigation is to evaluate the safety and effectiveness of the Cleaner Vac Thrombectomy System for the removal of thrombus in the peripheral venous vasculature in a real-world, all-comers population. This prospective, multi-center, open-label study will assess clinical outcomes, device performance, and procedural success across …
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A Randomized Phase II Study Comparing Cytarabine + Daunorubicin(7+3) vs (Daunorubicin and Cytarabine) Liposome, Cytarabine + Daunorubicin +Venetoclax, Azacitidine + Venetoclax, and (Daunorubicin and Cytarabine) Liposome+ Venetoclax in Patients Aged 59 or Younger Who are Considered High-Risk(Adverse) Acute Myeloid Leukemia as Determined by MYELOMATCH; AMyeloMATCH Clinical Trial

R
Rita Assi
18 years - 59 years
All genders
Phase 2
What is the purpose of this study?This phase II MyeloMATCH treatment trial tests whether the standard approach of cytarabine and daunorubicin in comparison to the following experimental regimens works to shrink cancer in patients with high risk acute myeloid leukemia (AML): 1) daunorubicin and cytarabine liposome alone; 2) cytarabine and …
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Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

J
Jessica Parker Metter
18 years - 100 years
Female
Phase 3
Interventional
What is the purpose of this study?The OnPrime study is a multi-center, randomized open-label phase 3 study evaluating the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab compared to the Active Comparator Arm with Physician's Choice of chemotherapy and bevacizumab in women diagnosed with platinum-resistant/refractory ovarian cancer …
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