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Found 701 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Effects of Investigational for Refractory Metastatic Colorectal Cancer in Minority Populations

A
Anita Turk, MD
18 years - 100 years
All genders
Phase 4
This study investigates the effects of an investigational medication on high blood pressure in patients with refractory metastatic colorectal cancer (mCRC) from minority groups, specifically Black/African American and Hispanic/Latino populations. High blood pressure, also known as hypertension, is when the force of blood against the artery walls is too high, …
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Investigating the Safety and Effects of an Investigational Antibody-Drug Conjugate in Solid Tumors

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 1
This study investigates the safety and effects of an investigational antibody-drug conjugate in patients with advanced or metastatic solid tumors. The purpose is to understand how the investigational medication works in the body and its impact on tumors. Advanced or metastatic solid tumors are cancers that have spread beyond their …
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Studying the Safety and Effectiveness of Bladder-Administered Therapy for BCG-Unresponsive Bladder Cancer

H
Hristos Kaimakliotis, MD
18 years - 100 years
All genders
Phase 2
This study investigates the safety and efficacy of intravesical nadofaragene firadenovec, either alone or in combination with chemotherapy or immunotherapy, in patients with high-grade Bacillus Calmette-Guerin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC). NMIBC is a type of bladder cancer that has not spread into the muscle layer of the …
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Investigating the Effects of an Investigational Medication on Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH) and Metabolic Dysfunction-Associated Steatohepatitis (MASH) with Fibrosis

R
Raj Vuppalanchi, MD
18 years - 80 years
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication on people with non-cirrhotic NASH (Nonalcoholic Steatohepatitis) or MASH (Metabolic Dysfunction-Associated Steatohepatitis) and fibrosis. NASH and MASH are conditions where fat builds up in the liver, causing inflammation and damage. The purpose of this study is to see if the investigational …
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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

S
Sherif Farag, MD
All genders
Observational
This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and otherdications.
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Testing the Addition of Chemotherapy Drug, Cisplatin, to Usual Radiation Therapy for Patients with Head and Neck Cancer

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 2
Interventional
The purpose of this study is to compare two treatment approaches that are currently used after surgery for head and neck cancer. One approach is to administer radiation therapy alone. A second approach is to administer radiation therapy along with the chemotherapy drug, cisplatin.
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A Phase II Study of Amivantamab SC (subcutaneous) in Participants with MET Amplification-Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study)

R
Rohan Maniar
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
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A Randomized Phase II Study Comparing Cytarabine + Daunorubicin(7+3) vs (Daunorubicin and Cytarabine) Liposome, Cytarabine + Daunorubicin +Venetoclax, Azacitidine + Venetoclax, and (Daunorubicin and Cytarabine) Liposome+ Venetoclax in Patients Aged 59 or Younger Who are Considered High-Risk(Adverse) Acute Myeloid Leukemia as Determined by MYELOMATCH; AMyeloMATCH Clinical Trial

R
Rita Assi
18 years - 59 years
All genders
Phase 2
What is the purpose of this study?This phase II MyeloMATCH treatment trial tests whether the standard approach of cytarabine and daunorubicin in comparison to the following experimental regimens works to shrink cancer in patients with high risk acute myeloid leukemia (AML): 1) daunorubicin and cytarabine liposome alone; 2) cytarabine and …
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Study on Autologous Stem Cell Transplant for Peripheral T-Cell Lymphoma in Remission

U
Utpal Dave, MD
18 years - 75 years
All genders
Phase 3
This study investigates the potential benefits of using high dose chemotherapy followed by a patient's own stem cells, known as an autologous stem cell transplant, in treating peripheral T-cell lymphoma. Peripheral T-cell lymphoma is a type of cancer that affects T-cells, which are part of the body's immune system. The …
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A Randomized Phase II Trial of Doxorubicin + Pembrolizumab Versus Doxorubicin Alone for the Treatment of Undifferentiated Pleomorphic Sarcoma (UPS) and Related Poorly Differentiated Sarcomas

S
Samantha Armstrong
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started to other places in the …
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