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Found 183 Cancer trials

A listing of Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating Levocarnitine for Reducing Liver Issues in Leukemia Treatment

R
Rachael Schulte
15 years - 40 years
All genders
This study investigates whether adding levocarnitine to chemotherapy regimens can reduce liver problems, specifically conjugated hyperbilirubinemia, in adolescents and young adults with Acute Lymphoblastic Leukemia (ALL). Conjugated hyperbilirubinemia is a condition where there is too much bilirubin, a substance made during the breakdown of red blood cells, in the blood. …
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A Randomized Phase II Trial of Doxorubicin + Pembrolizumab Versus Doxorubicin Alone for the Treatment of Undifferentiated Pleomorphic Sarcoma (UPS) and Related Poorly Differentiated Sarcomas

S
Samantha Armstrong
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started to other places in the …
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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

J
Jonathan L. Berkowitz, MD, PhD
18 years or above
All genders
Interventional
This randomized research trial studies how well serum tumor marker directed disease monitoring works in monitoring patients with hormone receptor positive Her2 negative breast cancer that has spread to other places in the body. Using markers to prompt when scans should be ordered may be as good as the usual …
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CD4CAR T CELL THERAPY FOR CMML

H
Huda Salman
18 years - 100 years
All genders
Researchers as the Indiana University Simon Comprehensive Cancer Center are conducting a study to research the safety and effectiveness of increasing doses of CD4CAR T cell therapy for patients who have been diagnosed with, or are being treated for, relapsed or refractory (has not responded to treatment) CD4+ chronic myelomonocytic …
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A Randomized Phase II Study of Letrozole Versus Observation in Patients with Newly Diagnosed Uterine Leiomyosarcoma

L
Lisa Landrum, MD, PhD, MS
18 years - 100 years
Female
Phase 2
What is the purpose of this study?This is a clinical trial to test letrozole in patients with uterine leiomyosarcoma. The main question is will treatment with letrozole extend progression-free survival in patients. Patients will receive 2/5 mg of letrozole daily. Translational Objectives: 1. To preliminarily assess IHC hormone receptor expression and correlation …
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Increasing Equity in Lung Cancer Screening

N
Nicholas R. Pettit
50 years - 80 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to is to improve the way physicians and scientists understand patient and provider attitudes towards Lung Cancer Screening. Lung Cancer Screening is a very important diagnostic measure to detect early-stage Lung Cancer in patients. This study is being …
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Research Study of an Investigational Device for Stress Urinary Incontinence After Prostate Surgery

M
Michael Koch, MD
45 years - 100 years
Male
This study investigates the use of an investigational device for men who have stress urinary incontinence after having their prostate removed because of cancer. Stress urinary incontinence happens when activities like coughing or lifting cause urine to leak. The purpose of this study is to see if the device is …
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Routine Carbohydrate Loading in Patients Undergoing Complex Hepatobiliary Surgery

T
Tom Korte Maatman
18 years - 100 years
All genders
What is the purpose of this study?Test the effect of preoperative carbohydrate loading on hospital LOS after complex hepatopancreaticobiliary surgeries.Test the effect of preoperative carbohydrate loading on other post-operative complications including surgical site infections (SSI), readmissions, delayed gastric emptying (DGE), insulin resistance and deathTHIS STUDY IS ENROLLING BY INVITATION ONLY …
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Master Screening and Reassessment Protocol (MSRP) for TierAdvancement in the NCI myeloMATCH Clinical Trials

R
Rita Assi
18 years - 100 years
All genders
What is the purpose of this study?This MyeloMATCH Master Screening and Reassessment Protocol (MSRP) evaluates the use of a screening tool and specific laboratory tests to help improve participants' ability to register to clinical trials throughout the course of their myeloid cancer (acute myeloid leukemia or myelodysplastic syndrome) treatment. This …
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Protocol for a Research Sample Repository for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries

J
Jodi Skiles
All genders
Observational
The primary purpose of the Research Sample Repository is to make blood samples available forh studies related to histocompatibility and hematopoietic cell transplantation (HCT)her cellular therapy. Representatives of participating centers and investigators or research groups may requesth samples contained in the Research Sample Repository for the purpose ofducting research including: …
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