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Found 169 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

J
Jodi Skiles
12 years - 80 years
All genders
This study investigates the use of investigational cryopreserved bone marrow for transplantation. The purpose is to provide a ready-to-use source of hematopoietic cell grafts for patients who do not have available living donors. Hematopoietic progenitor cells (HPCs) are special cells that can develop into different types of blood cells. This …
S
Sandeep Batra, MD
40 years or below
All genders
Phase 2/3
Interventional
This study investigates the use of an investigational medication, cabozantinib, in combination with standard chemotherapy for patients with newly diagnosed osteosarcoma. Osteosarcoma is a type of bone cancer that typically affects the long bones in the body. Cabozantinib is a kinase inhibitor, which means it works by blocking specific enzymes …
J
Jenny Belsky, DO
5 years - 60 years
All genders
Phase 3
Interventional
This study investigates the use of immunotherapy in treating Hodgkin lymphoma, a type of cancer that affects the lymphatic system. Hodgkin lymphoma is a condition where cells in the lymphatic system grow abnormally and may spread beyond it. The purpose of this study is to compare adding immunotherapy (brentuximab vedotin …
A
Anthony Ross
180 days - 22 years
All genders
Phase 2
Interventional
This study investigates an investigational medication for treating Langerhans cell histiocytosis (LCH), a disease where the body makes too many immature Langerhans cells, a type of white blood cell. These cells can build up and form tumors in organs like bones, skin, and lungs, causing damage. The purpose of the …
R
Rohan Maniar
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
S
Sharon E. Robertson
18 years - 100 years
Female
Phase 3
This study investigates treatment options for high risk locally advanced cervical cancer, where the cancer has spread to nearby tissues or lymph nodes. The study compares two approaches: one with induction chemotherapy using an investigational medication and chemotherapy, followed by chemoradiation and maintenance therapy, and the other with just chemoradiation …
S
Sherif Farag, MD
All genders
Observational
This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and otherdications.
A
Amanda J. Saraf, DO
1 year or below
All genders
Phase 2
This study investigates the addition of investigational medication and investigational immunotherapy to the usual chemotherapy for infants with newly diagnosed acute lymphoblastic leukemia (ALL). ALL is a type of cancer where the bone marrow makes too many immature lymphocytes (a type of white blood cell). In this study, the researchers …
B
Bryan Schneider, MD
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?This Phase III, randomized, open-label, multicenter study will evaluate the efficacy andy of giredestrant plus everolimus compared with the physician's choice of endocrineherapy plus everolimus in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer …
B
Brian Weiss
12 months - 22 years
All genders
Phase 1
This study investigates the safety and effects of an investigational medication when combined with radiation therapy in children with high grade glioma. High grade glioma is a type of cancer that occurs in the brain. The investigational medication works by blocking signals that make cancer cells grow, which may help …
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