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Found 147 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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C
Catherine Sears, MD
18 years - 100 years
Accepts healthy volunteer
All genders
This study investigates the DNA repair capacity (DRC) in lung disease. DRC is a measure of how well cells can fix damage to their DNA. High DNA damage is often found in lung diseases like lung cancer and chronic obstructive lung disease (COPD), which includes emphysema and chronic bronchitis. The …
G
Greg Durm, MD
18 years - 100 years
All genders
Phase 2
Interventional
The purpose of this study is to compare two treatment approaches that are currently used after surgery for head and neck cancer. One approach is to administer radiation therapy alone. A second approach is to administer radiation therapy along with the chemotherapy drug, cisplatin.
J
Jessica Parker Metter
35 years - 50 years
Female
This study investigates two surgical procedures for reducing the risk of ovarian cancer in individuals with BRCA1 mutations. The purpose of this study is to compare bilateral salpingectomy, which is the removal of the fallopian tubes, with bilateral salpingo-oophorectomy, which is the removal of both the fallopian tubes and ovaries, …
J
Jordan Holmes
18 years - 100 years
All genders
This study investigates how completing surveys about symptoms and quality of life during radiation treatment affects symptom management. The focus is on patients who speak English or Spanish and are undergoing treatment for certain cancers, like endometrial, cervical, or prostate cancer. The goal is to see if real-time feedback can …
L
Lisa Landrum, MD, PhD, MS
18 years - 100 years
Female
Phase 2
This study investigates the effectiveness of using a combination of investigational medications, nivolumab and ipilimumab, compared to nivolumab alone in treating patients with recurrent endometrial cancer. Endometrial cancer is a type of cancer that begins in the lining of the uterus. This study focuses on a specific type of endometrial …
A
Attaya Suvannasankha, MD
18 years - 95 years
All genders
This study investigates a treatment for multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. The purpose of the study is to see if the investigational treatment can improve cancer outcomes and bone health.Participants will have standard clinical assessments, such as blood draws and bone …
K
Kathy Miller, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates the effects of an investigational medication alone compared to the same medication combined with tocilizumab in patients with advanced breast cancer. Advanced breast cancer includes conditions such as metastatic triple negative or ER-low breast cancer. This study involves Black and non-Black patients and aims to understand how …
S
Suparna C. Clasen, MD, MSCE
18 years or above
All genders
Phase 3
Interventional
This study investigates the use of abatacept in patients who have myocarditis, a heart condition, after being treated with immune checkpoint inhibitors (ICI). The purpose is to see if abatacept can lower the risk of major adverse cardiac events (MACE), which include serious heart problems like heart attacks or heart …
N
Nawal Kassem
18 years - 100 years
All genders
This study investigates how to increase genetic testing in Black families with hereditary cancer syndromes. Hereditary cancer syndromes are conditions where gene changes increase the risk of cancer in families. The study focuses on Black patients who have been advised to undergo genetic testing. It aims to see if using …
M
Michael W. Sim, MD
18 years - 100 years
All genders
This study investigates a new approach for treating HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). The purpose of this study is to see if reducing the intensity of treatment, based on levels of ctHPVDNA (pieces of cancer DNA in blood samples), can be as effective as the standard treatment. OPSCC is …
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