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Found 155 Neoplasm trials
A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Rina Yadav
This study investigates the effects of an investigational medication on premenopausal women with a specific type of breast cancer called estrogen receptor-positive, HER2-negative breast cancer. The purpose of the study is to understand how the investigational medication affects tumor cell growth compared to other treatments. The study is divided into …
A Study of DSP107 Alone and in Combination With Atezolizumab for Patients With Advanced Solid Tumors
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Rohan Maniar
What is the purpose of this study?Part 1: A first-in-human, open-label, Phase I dose escalation study of DSP107 monotherapy and combination therapy with atezolizumab in patients with advanced solid tumors. Part 2: Preliminary efficacy assessment of DSP107 in combination with atezolizumab in second or third line treatment of non small …
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Scott Coven
What is the purpose of this study?The Biobank being created by this study is located at the Hospital for Sick Children in Toronto, Canada and is a research registry that collects biological samples and medical information from individuals in participating centers around the world. The purpose of this registry is …
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Marissa Just
What is the purpose of this study?This phase II trial studies how well combination chemotherapy works in treating patients withwly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens suchH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, …
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Marissa Just
This study investigates treatment strategies for children with favorable histology Wilms tumors (FHWT), which is a common type of kidney cancer in children. The study aims to use risk factors, such as tumor histology, biology, and response to therapy, to determine the most effective treatment plan. Wilms Tumor is a …
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James Croop, MD, PhD
This study is designed to investigate whether the use of copanlisib is safe, feasible and beneficial to pediatric patients with solid solid tumors or lymphoma that are recurrent or refractory to standard therapy.
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Mitesh Shah, MD
What is the purpose of this study?The objectives of this registry study are to evaluate real-world clinical outcomes andd outcomes that measure the effectiveness and safety of STaRT.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their …
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Sandeep Batra, MD
What is the purpose of this study?This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients withgerminomatous germ cell tumors (NGGCT) that have not spread to other parts of the brainbody (localized). This study has …
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Scott Coven
This study investigates Atypical Teratoid Rhabdoid Tumor (ATRT) in children. ATRT is a rare and fast-growing cancerous tumor that usually starts in the brain and spinal cord. The purpose of this study is to understand how different treatments and clinical factors affect the disease and to create a collection of …
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Brian Weiss
What is the purpose of this study?This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits ofgavivint in treating patients with solid tumors that has come back (recurrent) or does notd to treatment (refractory). Tegavivint interferes with the binding of beta-catenin to TBL1, which may help …
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