A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
What is the purpose of this study?This Phase III Trial evaluates whether breast conservation surgery and endocrine therapyults in a non-inferior rate of invasive or non-invasive ipsilateral breast tumorurrence (IBTR) compared to breast conservation with breast radiation and endocrineherapy.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology …
What is the purpose of this study? The purpose of this research study is to: Test whether the TULSA Study Procedure preserves or improves your quality of life (urinary, bowel and sexual functions) at 12 months post-study treatment compared to standard of care (radical prostatectomy). Test how many subjects who …
What is the purpose of this study?The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for …
What is the purpose of this study?Subjects with cT2-T3N0M0 urothelial cancer of the bladder will be enrolled. After completingwo cycles of pembrolizumab, subjects will undergo a restaging MRI of the abdomen and pelvis with a standard acquisition protocol (as outlined in the protocol) as well as CT chest. A CThe …
What is the purpose of this study?This phase II trial studies whether adding pembrolizumab to olaparib (standard of care) works better than olaparib alone in treating patients with pancreatic cancer with germline BRCA1 or BRCA2 mutations that has spread to other places in the body (metastatic). BRCA1 and BRCA2 are …
What is the purpose of this study?This phase II trial studies the effects of temozolomide and atezolizumab as second or thirdwith small cell lung cancer that has spread to other places inhe body (metastatic) or has come back (recurrent). Chemotherapy drugs, such as temozolomide, work in different ways to stop …
What is the purpose of this study?This Phase III, randomized, open-label, multicenter study will evaluate the efficacy andy of giredestrant plus everolimus compared with the physician's choice of endocrineherapy plus everolimus in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer …
What is the purpose of the study?The purpose of this study is to examine rare cells called circulating tumor cells that are present in a person's blood when they have lung cancer to see if there is a relationship between a person's cancer symptoms and the number and characteristics of …
What is the purpose of this study?Adult patients (18 years of age and older) and pediatric patients (younger than 18 years of age) who are being evaluated for and/or treated for cancer at the NIH Clinical Center and at participating sites will be entered onto this tissue procurement protocol for …
What is the purpose of this study?The goal of this study is to identify and validate response to therapy biomarkers for NIV respiratory support in children with ICCs. The central hypothesis is that response-to-therapy biomarkers can identify those most likely to benefit from intervention with NIV. The rationale is that …
