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Found 163 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

H
Hristos Kaimakliotis, MD
18 years - 100 years
All genders
Phase 2
This study investigates the safety and efficacy of intravesical nadofaragene firadenovec, either alone or in combination with chemotherapy or immunotherapy, in patients with high-grade Bacillus Calmette-Guerin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC). NMIBC is a type of bladder cancer that has not spread into the muscle layer of the …
T
Tarah Ballinger, MD
18 years - 45 years
Female
Phase 2
This study investigates the effect of low-dose aspirin on inflammation markers in postpartum patients with benign breast disease. Postpartum refers to the period after childbirth. Chronic inflammation may increase the risk of developing breast cancer after having a baby. Low-dose aspirin is a type of medication that reduces inflammation and …
S
Sandeep Batra, MD
40 years or below
All genders
Phase 2/3
Interventional
This study investigates the use of an investigational medication, cabozantinib, in combination with standard chemotherapy for patients with newly diagnosed osteosarcoma. Osteosarcoma is a type of bone cancer that typically affects the long bones in the body. Cabozantinib is a kinase inhibitor, which means it works by blocking specific enzymes …
A
Anthony Ross
180 days - 22 years
All genders
Phase 2
Interventional
This study investigates an investigational medication for treating Langerhans cell histiocytosis (LCH), a disease where the body makes too many immature Langerhans cells, a type of white blood cell. These cells can build up and form tumors in organs like bones, skin, and lungs, causing damage. The purpose of the …
H
Huda Salman
18 years - 100 years
All genders
Phase 1
This study investigates the safety of an investigational treatment using special immune cells called CAR-T cells for people with certain B cell cancers. B cell malignancies are cancers that affect a type of white blood cell. The study includes participants whose cancer has returned or not responded to previous treatments. …
R
Rohan Maniar
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
S
Sherif Farag, MD
All genders
Observational
This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and otherdications.
B
Brian Weiss
12 months - 22 years
All genders
Phase 1
This study investigates the safety and effects of an investigational medication when combined with radiation therapy in children with high grade glioma. High grade glioma is a type of cancer that occurs in the brain. The investigational medication works by blocking signals that make cancer cells grow, which may help …
S
Sandeep Batra, MD
2 years - 21 years
All genders
Phase 3
Interventional
This study investigates treatment options for children and young adults with low-grade glioma (LGG), a type of brain tumor. The purpose of this study is to compare the effects of an investigational medication with standard chemotherapy treatments, carboplatin and vincristine, in patients who do not have a specific genetic mutation …
S
Sandeep Batra, MD
12 months - 21 years
All genders
Phase 1/2
Interventional
This study investigates the safety and effectiveness of combining an investigational medication with standard radiation therapy in treating children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG) or high-grade glioma (HGG). Glioma is a type of cancer that occurs in the brain or spine, and it is …
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