A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the safety of an investigational treatment using special immune cells called CAR-T cells for people with certain B cell cancers. B cell malignancies are cancers that affect a type of white blood cell. The study includes participants whose cancer has returned or not responded to previous treatments. …
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and otherdications.
This study investigates the safety and effects of an investigational medication when combined with radiation therapy in children with high grade glioma. High grade glioma is a type of cancer that occurs in the brain. The investigational medication works by blocking signals that make cancer cells grow, which may help …
This study investigates treatment options for children and young adults with low-grade glioma (LGG), a type of brain tumor. The purpose of this study is to compare the effects of an investigational medication with standard chemotherapy treatments, carboplatin and vincristine, in patients who do not have a specific genetic mutation …
This study investigates the safety and effectiveness of combining an investigational medication with standard radiation therapy in treating children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG) or high-grade glioma (HGG). Glioma is a type of cancer that occurs in the brain or spine, and it is …
What is the purpose of this study?This phase II trial studies how well lower dose radiotherapy after chemotherapy works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class …
This study investigates whether adding levocarnitine to chemotherapy regimens can reduce liver problems, specifically conjugated hyperbilirubinemia, in adolescents and young adults with Acute Lymphoblastic Leukemia (ALL). Conjugated hyperbilirubinemia is a condition where there is too much bilirubin, a substance made during the breakdown of red blood cells, in the blood. …
What is the purpose of this study?This phase II trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started to other places in the …
