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Found 155 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

P
Pravin Kaumaya
18 years - 100 years
All genders
Phase 1
What is the purpose of this study?Primary Objectives1. To determine the safety and toxicity profile of a chimeric HER2 B-cell peptide vaccine in patients with high-risk HER2 positive breast cancer after completion of standard curative therapy and adjuvant HER2-directed antibody therapy2. To determine immune responses induced by a chimeric HER2 …
E
Emily Mueller, MD
17 years or below
All genders
What is the purpose of this study?The purpose of this study is to study the transition from an inpatient hospital admission to being at home by engaging with caregivers (parents, legal guardians, etc) of children of cancer as well as with healthcare providers that participate in this process with the …
J
Jessica Parker Metter
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This phase III trial compares the effect of olaparib for one year versus two years, with or without bevacizumab, for the treatment of BRCA 1/2 mutated or homologous recombination deficient stage III or IV ovarian cancer. Olaparib is a polyadenosine 5'-diphosphoribose polymerase (PARP) enzyme …
T
Thomas E. Davis
18 years - 100 years
All genders
The purpose of this study is to evaluate an investigational system using clinical blood samples. This study investigates its performance by comparing results from the investigational system to established methods. The study involves three arms: Method Comparison, Whole Blood Precision, and WBC Flagging. Method Comparison assesses how closely the investigational …
C
Catherine Sears, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?The DNA repair capacity (DRC) is a measure of a cell’s ability to repair DNA damage. High levels of DNA damage are observed in many lung diseases, including lung cancer and chronic obstructive lung disease (COPD, sometimes referred to as emphysema or chronic bronchitis). …
S
Shelley Johns
18 years or above
Male
What is the purpose of this study?In this 3-phase pilot, we will identify adverse health outcomes and unmet support needs of testicular cancer survivors (TCS) (Phase 1) and employ participatory co-design to adapt an existing acceptance and commitment therapy (ACT)-based intervention with a sample of up to 8 TCS (Phase …
R
Rafat Abonour, MD
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?The goal of this study (iMMagine-3) is to compare the study drug, anitocabtagene autoleucel to standard of care therapy (SOCT) in participants with relapsed/refractory multiple myeloma who have received 1 to 3 prior lines of therapy, including an anti-CD38 monoclonal antibody and an immunomodulatory …
N
Nawal Kassem
18 years - 100 years
All genders
What is the purpose of this study?The purpose of this study to understand how patients cope with a hereditary cancer diagnosis, and what factors affect, either positively or negatively, the patient’s ability to cope with their diagnosis.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients …
K
Kathy Miller, MD
18 years - 100 years
All genders
This study investigates ways to support people with breast cancer who are taking oral anticancer medications. Breast cancer is a disease where cells in the breast grow out of control. Oral anticancer medications are drugs taken by mouth to help treat cancer. The purpose of this study is to develop …
G
Greg Durm, MD
18 years - 100 years
All genders
Phase 2
Interventional
The purpose of this study is to compare two treatment approaches that are currently used after surgery for head and neck cancer. One approach is to administer radiation therapy alone. A second approach is to administer radiation therapy along with the chemotherapy drug, cisplatin.
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