A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work inventing breast cancer from coming back (relapsing) in patients with high risk, HER2ve breast cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to ahemotherapy drug, called DM1. Trastuzumab is a form of targeted therapy because it …
What is the purpose of this study?Define and follow-up with the patients that undergo OTC for fertility preservation.Optimize techniques and quality assurance measures for freezing and thawing of ovarian tissue or gametesEstablish techniques for in vitro follicle maturation (IFM) or in vitro maturation of cumulus oocyte complexesInvestigate factors affecting successful …
What is the purpose of this study?The purpose of this study is to better understand how parents of infants and young children (3 years of age and under) experience the stem cell transplant process. More specifically, we want to understand if and how stem cell transplant impacts parenting so that …
What is the purpose of this study?This study will assess if adding sacituzumab tirumotecan with pembrolizumab after surgery is effective in treating NSCLC for participants not achieving pathological complete response. The primary hypothesis of this study is sacituzumab tirumotecan plus pembrolizumab is superior to pembrolizumab monotherapy with respect to disease …
What is the purpose of this study?To evaluate the efficacy of divarasib compared with KRAS G12C inhibitors (sotorasib or adagrasib)To evaluate the efficacy of divarasib compared with KRAS G12C inhibitors (sotorasib or adagrasib)To evaluate, from the participant's perspective, the functioning and impact of key disease-related symptoms of participants treated with …
Why is this study being done?Testicular cancer (TC) is diagnosed in young adult males between ages 18-39 and TC treatment involves the use of platinum therapy (CBCT) which can have long-term cardiovascular effects. We are looking at cholesterol and hormone changes, as well as blood vessel changes for coronary artery …
What is the purpose of this study?2.1 Primary ObjectiveIdentify early axonal damage patterns, and correlate findings with genes, biomarkers, and existing clinically validated clinician neuropathic reporting tools.2.2 Secondary ObjectivesCharacterize the longitudinal pattern of axonal damage in CAYAs with cancer receiving VCR.Investigate the correlation between novel biomarkers of axonal damage and …
What is the purpose of this study?This is a descriptive, cross-sectional study, which will involve a one-time survey for patients with lung cancer (any histology), pancreatic adenocarcinoma, renal cell carcinoma, and urothelial carcinoma. Patients in this study will be recruited in a prospective basis during their in-person visit to the outpatient …
What is the purpose of this study?This phase III trial studies magnetic resonance imaging (MRI) surveillance and prophylactic cranial irradiation (PCI) to see how well they work compared to MRI surveillance alone in treating patients with small cell lung cancer. MRI scans are used to monitor the possible spread of …
What is the purpose of this study?This phase II trial tests whether low-dose aspirin can affect markers of inflammation in postpartum (after childbirth) patients with benign breast disease planning to have a breast biopsy. Chronic inflammation may increase the risk of postpartum related breast cancer. Low-dose aspirin is a non-steroidal …
