A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
What is the purpose of this study?Define and follow-up with the patients that undergo OTC for fertility preservation.Optimize techniques and quality assurance measures for freezing and thawing of ovarian tissue or gametesEstablish techniques for in vitro follicle maturation (IFM) or in vitro maturation of cumulus oocyte complexesInvestigate factors affecting successful …
The aim of this Expanded Access Program (EAP) is to enable the use of 89Zr-DFO-girentuximab with positron emission tomography/computed tomography (PET/CT) imaging to noninvasively detect carbonic anhydrase 9 (CAIX)-expressing clear cell renal cell carcinoma (ccRCC) in patients with renal masses as determined by conventional imaging.Generate additional safety and real-world data …
What is the purpose of this study?This study will assess if adding sacituzumab tirumotecan with pembrolizumab after surgery is effective in treating NSCLC for participants not achieving pathological complete response. The primary hypothesis of this study is sacituzumab tirumotecan plus pembrolizumab is superior to pembrolizumab monotherapy with respect to disease …
What is the purpose of this study?To evaluate the efficacy of divarasib compared with KRAS G12C inhibitors (sotorasib or adagrasib)To evaluate the efficacy of divarasib compared with KRAS G12C inhibitors (sotorasib or adagrasib)To evaluate, from the participant's perspective, the functioning and impact of key disease-related symptoms of participants treated with …
What is the purpose of this study?2.1 Primary ObjectiveIdentify early axonal damage patterns, and correlate findings with genes, biomarkers, and existing clinically validated clinician neuropathic reporting tools.2.2 Secondary ObjectivesCharacterize the longitudinal pattern of axonal damage in CAYAs with cancer receiving VCR.Investigate the correlation between novel biomarkers of axonal damage and …
What is the purpose of this study?This is a descriptive, cross-sectional study, which will involve a one-time survey for patients with lung cancer (any histology), pancreatic adenocarcinoma, renal cell carcinoma, and urothelial carcinoma. Patients in this study will be recruited in a prospective basis during their in-person visit to the outpatient …
What is the purpose of this study?This phase III trial studies magnetic resonance imaging (MRI) surveillance and prophylactic cranial irradiation (PCI) to see how well they work compared to MRI surveillance alone in treating patients with small cell lung cancer. MRI scans are used to monitor the possible spread of …
What is the purpose of this study?This phase II trial tests whether low-dose aspirin can affect markers of inflammation in postpartum (after childbirth) patients with benign breast disease planning to have a breast biopsy. Chronic inflammation may increase the risk of postpartum related breast cancer. Low-dose aspirin is a non-steroidal …
This phase II trial tests the safety, side effects, best dose and activity of tovorafenib (DAY101) in treating patients with Langerhans cell histiocytosis that is growing, spreading, or getting worse (progressive), has come back (relapsed) after previous treatment, or does not respond to therapy (refractory). Langerhans cell histiocytosis is a …
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
