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Found 166 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Testing the Addition of Chemotherapy Drug, Cisplatin, to Usual Radiation Therapy for Patients with Head and Neck Cancer

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 2
Interventional
The purpose of this study is to compare two treatment approaches that are currently used after surgery for head and neck cancer. One approach is to administer radiation therapy alone. A second approach is to administer radiation therapy along with the chemotherapy drug, cisplatin.
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Studying Heart Health and Knowledge in Men with Prostate Cancer

S
Suparna C. Clasen, MD, MSCE
J
Jordan Holmes
18 years - 100 years
Male
This study investigates cardiovascular health literacy and risk among men with prostate cancer. The purpose is to compare these factors between African American and White men who are receiving or have completed androgen deprivation therapy, which is a treatment that reduces male hormones to slow cancer growth. The study also …
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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

S
Sandeep Batra, MD
21 years or below
All genders
Phase 3
Interventional
What is the purpose of this study?This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acuteyeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop …
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A Phase 2 Study Using Chemoimmunotherapy With Gemcitabine, Cisplatin and Nivolumab in Newly Diagnosed Nasopharyngeal Carcinoma (NPC)

M
Marissa Just
1 years - 21 years
All genders
Phase 2
This phase II trial tests how well nivolumab in combination with chemotherapy drugs along with radiation therapy works in treating patients with nasopharyngeal cancer. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to …
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Study of Investigational Medication vs Standard Treatments in Cancer That Has Spread

N
Nabil Adra, MD
18 years - 100 years
Male
Phase 3
This study investigates the treatment of metastatic castration-resistant prostate cancer (mCRPC), which is a type of cancer that continues to grow even when the amount of testosterone in the body is reduced to very low levels. The purpose of this study is to compare overall survival between participants receiving an …
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Study on Treatment for High-risk Renal Cell Carcinoma

J
Jennifer King
18 years - 100 years
All genders
This study investigates the effects of adding an investigational medication to a standard treatment for patients with high-risk renal cell carcinoma (RCC). RCC is a type of kidney cancer. The purpose of this study is to see if the investigational medication, when combined with the standard treatment, works better than …
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Study on Decision-Making and Usability of Resources for Chronic Lymphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL) Patients

L
Larry Cripe, MD
18 years - 100 years
All genders
This study investigates how patients with CLL/SLL make decisions about their treatment options. CLL stands for chronic lymphocytic leukemia, and SLL stands for small lymphocytic lymphoma, both of which are types of blood cancers. The study aims to understand patient perspectives on choosing between different treatments and to gather feedback …
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A Randomized Phase III Study to Evaluate Benefits of Autologous Stem Cell Transplant in Patients with Peripheral T Cell Lymphoma that Achieved a First Complete Remission (CR1) Following Induction Therapy (PTCL-STAT)

U
Utpal Dave, MD
18 years - 75 years
All genders
Phase 3
Primary: To demonstrate improvement in progression free survival (PFS) in the autologous stem cell transplant (ASCT) arm compared to the observation arm. Secondary: -To assess difference in overall survival (OS) between the observation and autologous stem cell transplant (ASCT) arm. -To evaluate the differences in study intervention benefit for PFS …
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Study on Investigational Cord Blood Units

J
Jodi Skiles
100 years or below
All genders
This study investigates the safety of using investigational cord blood units (CBUs) for hematopoietic stem cell transplants in both children and adults. Hematopoietic stem cells are important for creating new blood cells. The study will carefully look at any problems that happen during or after the infusion of these CBUs.Participants …
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Investigation of Blood Samples from Stage IV Non-Small Cell Lung Cancer Patients

V
Vijay Khatri
100 years or below
All genders
This study investigates the collection of fresh blood from patients with Stage IV Non-Small Cell Lung Cancer (NSCLC). NSCLC is a type of lung cancer that is characterized by the uncontrolled growth of cells in the lung tissue. Stage IV indicates that the cancer has spread beyond the lungs to …
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