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Found 165 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study of Investigational Medication vs Standard Treatments in Cancer That Has Spread

N
Nabil Adra, MD
18 years - 100 years
Male
Phase 3
This study investigates the treatment of metastatic castration-resistant prostate cancer (mCRPC), which is a type of cancer that continues to grow even when the amount of testosterone in the body is reduced to very low levels. The purpose of this study is to compare overall survival between participants receiving an …
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Study on Treatment for High-risk Renal Cell Carcinoma

J
Jennifer King
18 years - 100 years
All genders
This study investigates the effects of adding an investigational medication to a standard treatment for patients with high-risk renal cell carcinoma (RCC). RCC is a type of kidney cancer. The purpose of this study is to see if the investigational medication, when combined with the standard treatment, works better than …
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A Randomized Phase III Study to Evaluate Benefits of Autologous Stem Cell Transplant in Patients with Peripheral T Cell Lymphoma that Achieved a First Complete Remission (CR1) Following Induction Therapy (PTCL-STAT)

U
Utpal Dave, MD
18 years - 75 years
All genders
Phase 3
Primary: To demonstrate improvement in progression free survival (PFS) in the autologous stem cell transplant (ASCT) arm compared to the observation arm. Secondary: -To assess difference in overall survival (OS) between the observation and autologous stem cell transplant (ASCT) arm. -To evaluate the differences in study intervention benefit for PFS …
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Investigating Imaging Techniques for Detecting Metastatic Disease in Pancreatic Cancer

C
Cindy Yuan
18 years or above
All genders
This study investigates the use of a special imaging test called [¹⁸F]FAPI-74 PET/CT to find cancer that has spread in people with a type of pancreatic cancer known as pancreatic ductal adenocarcinoma. Pancreatic ductal adenocarcinoma is a disease where cancer cells form in the tissues of the pancreas. The purpose …
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Study on Investigational Cord Blood Units

J
Jodi Skiles
100 years or below
All genders
This study investigates the safety of using investigational cord blood units (CBUs) for hematopoietic stem cell transplants in both children and adults. Hematopoietic stem cells are important for creating new blood cells. The study will carefully look at any problems that happen during or after the infusion of these CBUs.Participants …
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Investigation of Blood Samples from Stage IV Non-Small Cell Lung Cancer Patients

V
Vijay Khatri
100 years or below
All genders
This study investigates the collection of fresh blood from patients with Stage IV Non-Small Cell Lung Cancer (NSCLC). NSCLC is a type of lung cancer that is characterized by the uncontrolled growth of cells in the lung tissue. Stage IV indicates that the cancer has spread beyond the lungs to …
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Ovarian Tissue Cryopreservation for Fertility Preservation in Pre and Post-Pubertal Children, Adolescents and Adults Facing a Fertility Threatening Diagnosis or Treatment Regimen

A
Amanda J. Saraf, DO
17 years or below
Female
What is the purpose of this study?Define and follow-up with the patients that undergo OTC for fertility preservation.Optimize techniques and quality assurance measures for freezing and thawing of ovarian tissue or gametesEstablish techniques for in vitro follicle maturation (IFM) or in vitro maturation of cumulus oocyte complexesInvestigate factors affecting successful …
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Investigating Music Interventions for Reducing Stress in Young Children Undergoing a Procedure to Replace Damaged Cells

S
Sheri Robb
3 years or below
All genders
This study investigates how music can help reduce stress in young children undergoing stem cell transplants and their parents. The purpose is to adapt a music-based intervention called Active Music Engagement (AME) for children under 3 years old and their parents. This adaptation aims to decrease distress and improve coping …
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Investigating the Addition of Venetoclax to Chemotherapy in Children with Relapsed Acute Myeloid Leukemia (AML)

S
Sandeep Batra, MD
29 days - 21 years
All genders
Phase 3
This study investigates the treatment of acute myeloid leukemia (AML) in children, adolescents, and young adults who have experienced a relapse. The purpose is to see if adding an investigational medication to a standard chemotherapy treatment can improve outcomes. Acute myeloid leukemia is a type of cancer that affects the …
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Urinary Trypsinogen-2 for Detecting Pancreatitis After Pancreas Surgery

N
Nicholas Zyromski, MD
18 years - 100 years
All genders
This study investigates the use of urinary trypsinogen-2 to detect post-pancreatectomy acute pancreatitis (PPAP). Pancreatectomy is a surgery to remove part or all of the pancreas. PPAP is a condition that can occur after this surgery, where the pancreas becomes inflamed. The purpose of this study is to see if …
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