A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
What is the purpose of this study?To compare cardiovascular health literacy, cardiovascular risk, and cardiovascular disease between African American and White men who are receiving or completed androgen deprivation for treatment of prostate cancer. To explore clinical, socioeconomic, and demographic predictors of CVD health literacy. THIS STUDY IS ENROLLING BY INVITATION …
This study investigates the safety and effects of using an investigational medication with irinotecan to treat young patients with solid tumors that have returned or not responded to treatment. Solid tumors are masses of tissue that form when cells grow uncontrollably. The investigational medication is designed to target and break …
What is the purpose of this study?This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acuteyeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop …
What is the purpose of this study?This is a multicenter, randomized, open label phase lll trial to assess whether preoperative chemotherapy, as an adjunct to curative-intent surgery, improves the prognosis of high risk DDLPS (dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease free survival. Interested in participating? For more …
What is the purpose of this study?The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitabine in all randomized patients. Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer …
This study investigates the effects of adding an investigational medication to a standard treatment for patients with high-risk renal cell carcinoma (RCC). RCC is a type of kidney cancer. The purpose of this study is to see if the investigational medication, when combined with the standard treatment, works better than …
What is the purpose of this study?Define and follow-up with the patients that undergo OTC for fertility preservation.Optimize techniques and quality assurance measures for freezing and thawing of ovarian tissue or gametesEstablish techniques for in vitro follicle maturation (IFM) or in vitro maturation of cumulus oocyte complexesInvestigate factors affecting successful …
What is the purpose of this study?This study will assess if adding sacituzumab tirumotecan with pembrolizumab after surgery is effective in treating NSCLC for participants not achieving pathological complete response. The primary hypothesis of this study is sacituzumab tirumotecan plus pembrolizumab is superior to pembrolizumab monotherapy with respect to disease …
What is the purpose of this study?To evaluate the efficacy of divarasib compared with KRAS G12C inhibitors (sotorasib or adagrasib)To evaluate the efficacy of divarasib compared with KRAS G12C inhibitors (sotorasib or adagrasib)To evaluate, from the participant's perspective, the functioning and impact of key disease-related symptoms of participants treated with …
This study investigates muscle-invasive bladder cancer, a type of cancer that grows into the muscle layer of the bladder. The purpose is to see how well an investigational medication combined with another treatment works for this type of cancer. The study involves patients with muscle-invasive bladder cancer receiving treatment and …
