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Found 151 Neoplasm trials
A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Hristos Kaimakliotis, MD
This study investigates the safety and efficacy of intravesical nadofaragene firadenovec, either alone or in combination with chemotherapy or immunotherapy, in patients with high-grade Bacillus Calmette-Guerin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC). NMIBC is a type of bladder cancer that has not spread into the muscle layer of the …
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Jodi Skiles
This study investigates the use of investigational cryopreserved bone marrow for transplantation. The purpose is to provide a ready-to-use source of hematopoietic cell grafts for patients who do not have available living donors. Hematopoietic progenitor cells (HPCs) are special cells that can develop into different types of blood cells. This …
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Scott Coven
This study investigates the effects of two investigational medications, trametinib and everolimus, on young patients with gliomas that have returned. Gliomas are a type of brain tumor. Trametinib targets a protein in cells called MEK, which helps stop tumor growth. Everolimus blocks another pathway in tumor cells that can help …
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Tarah Ballinger, MD
This study investigates the effect of low-dose aspirin on inflammation markers in postpartum patients with benign breast disease. Postpartum refers to the period after childbirth. Chronic inflammation may increase the risk of developing breast cancer after having a baby. Low-dose aspirin is a type of medication that reduces inflammation and …
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Sandeep Batra, MD
This study investigates the use of an investigational medication, cabozantinib, in combination with standard chemotherapy for patients with newly diagnosed osteosarcoma. Osteosarcoma is a type of bone cancer that typically affects the long bones in the body. Cabozantinib is a kinase inhibitor, which means it works by blocking specific enzymes …
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Jenny Belsky, DO
This study investigates the use of immunotherapy in treating Hodgkin lymphoma, a type of cancer that affects the lymphatic system. Hodgkin lymphoma is a condition where cells in the lymphatic system grow abnormally and may spread beyond it. The purpose of this study is to compare adding immunotherapy (brentuximab vedotin …
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Anthony Ross
This study investigates an investigational medication for treating Langerhans cell histiocytosis (LCH), a disease where the body makes too many immature Langerhans cells, a type of white blood cell. These cells can build up and form tumors in organs like bones, skin, and lungs, causing damage. The purpose of the …
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Rohan Maniar
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
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Sharon E. Robertson
This study investigates treatment options for high risk locally advanced cervical cancer, where the cancer has spread to nearby tissues or lymph nodes. The study compares two approaches: one with induction chemotherapy using an investigational medication and chemotherapy, followed by chemoradiation and maintenance therapy, and the other with just chemoradiation …
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Amanda J. Saraf, DO
This study investigates the addition of investigational medication and investigational immunotherapy to the usual chemotherapy for infants with newly diagnosed acute lymphoblastic leukemia (ALL). ALL is a type of cancer where the bone marrow makes too many immature lymphocytes (a type of white blood cell). In this study, the researchers …
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