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Found 151 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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J
Jignesh Tailor
30 days - 21 years
All genders
This study investigates pediatric adamantinomatous craniopharyngioma, a type of brain tumor. Craniopharyngioma is a condition where a non-cancerous tumor forms near the pituitary gland, which is located at the base of the brain. This study aims to identify biological targets that could lead to new medical therapies, as current treatments …
S
Shelley Johns
18 years - 100 years
Female
This study investigates the fear of cancer occurrence in women who are at a higher risk of developing breast cancer but have not been diagnosed. These women are known as 'previvors.' The purpose of this study is to create a new measure to understand their fear better. Two existing tools …
B
Brian Weiss
12 years - 39 years
All genders
Phase 2
Interventional
This phase II trial studies the effects of trastuzumab deruxtecan in treating patients with HER2 positive osteosarcoma that is newly diagnosed or has come back (recurrent). Trastuzumab deruxtecan is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug called deruxtecan. Trastuzumab attaches to HER2 positive cancer cells in a …
T
Tim Lautenschlaeger, MD
18 years - 100 years
Accepts healthy volunteer
All genders
What is the purpose of this study?This study aims to invent a test that can see tiny pieces from people with cancer (specifically DNA from a person’s cancer) in blood and urine better than tests that can currently be done. In the future, this test can possibly be used to …
M
Marissa Just
1 years - 30 years
All genders
Phase 3
This study investigates the effectiveness of adding an investigational medication to standard chemotherapy and other treatments in children with high-risk neuroblastoma. Neuroblastoma is a type of cancer that usually affects young children and develops from immature nerve cells. The investigational medication is a monoclonal antibody that targets a molecule found …
P
Patrick Loehrer, MD
1 years - 100 years
All genders
What is this study about?The major purpose of this research study is to obtain blood samples from child and adult patients diagnosed with thymoma and/or tissue samples from patients undergoing surgery for their thymoma.  We will use these specimens to test for certain characteristics that we think will be useful …
S
Sandeep Batra, MD
21 years or below
All genders
Phase 3
Interventional
What is the purpose of this study?This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acuteyeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop …
S
Sandeep Batra, MD
1 month - 21 years
All genders
Phase 1/2
This study investigates treatment options for juvenile myelomonocytic leukemia (JMML), a rare type of blood cancer that affects young children. JMML is a condition where the bone marrow makes too many white blood cells, which can lead to various health problems. The purpose of this study is to test the …
M
Miriam Kim, DO
17 years or below
All genders
In this prospective and longitudinal natural history study, the aim is to identify variables that affect long-term outcomes following potentially life-saving Definitive Therapy (DT), which includes either 1) allogeneic hematopoietic cell transplant (HCT), or 2) autologous gene therapy (GT).
M
Marissa Just
1 years - 21 years
All genders
Phase 2
This phase II trial tests how well nivolumab in combination with chemotherapy drugs along with radiation therapy works in treating patients with nasopharyngeal cancer. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to …
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