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Found 167 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Rapid Autopsy Program for Small Cell Lung Cancer

S
Shadia Jalal, MD
18 years or above
All genders
The purpose of this study is to investigate a rapid autopsy program for patients with Small Cell Lung Cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center. Small Cell Lung Cancer is a type of lung cancer characterized by fast-growing tumors. This study will involve collecting tumor tissue from …
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RDCRN PIDTC

M
Miriam Kim, DO
17 years or below
All genders
In this prospective and longitudinal natural history study, the aim is to identify variables that affect long-term outcomes following potentially life-saving Definitive Therapy (DT), which includes either 1) allogeneic hematopoietic cell transplant (HCT), or 2) autologous gene therapy (GT).
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MODERN: An Integrated Phase 2/3 and Phase 3 Trial of MRD-Based Optimization of ADjuvant ThErapy in URothelial CaNcer

T
Tareq Salous
18 years - 100 years
All genders
Phase 2/3
What is this study about?This phase II/III trial examines whether patients who have undergone surgical removal of bladder, but require an additional treatment called immunotherapy to help prevent their bladder cancer from coming back, can be identified by a blood test. Many types of tumors tend to lose cells or …
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A Phase 2 Study Using Chemoimmunotherapy With Gemcitabine, Cisplatin and Nivolumab in Newly Diagnosed Nasopharyngeal Carcinoma (NPC)

M
Marissa Just
1 years - 21 years
All genders
Phase 2
This phase II trial tests how well nivolumab in combination with chemotherapy drugs along with radiation therapy works in treating patients with nasopharyngeal cancer. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to …
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Investigating the Use of a Blood Test for Cancer Markers in Advanced Lung Cancer Treatment

N
Nasser Hanna, MD
18 years - 100 years
All genders
Phase 2
Interventional
This study investigates the use of circulating tumor DNA (ctDNA) to personalize treatment for patients with stage III non-small cell lung cancer (NSCLC). The purpose is to use ctDNA analysis to guide therapy decisions, instead of relying solely on clinical or radiographic evidence of disease. This approach aims to tailor …
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Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer (DeLLphi-304)

G
Greg Durm, MD
18 years or above
All genders
Phase 3
Interventional
What is the purpose of this study?The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for …
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Study on Treatment for High-risk Renal Cell Carcinoma

J
Jennifer King
18 years - 100 years
All genders
This study investigates the effects of adding an investigational medication to a standard treatment for patients with high-risk renal cell carcinoma (RCC). RCC is a type of kidney cancer. The purpose of this study is to see if the investigational medication, when combined with the standard treatment, works better than …
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Study on Decision-Making and Usability of Resources for Chronic Lymphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL) Patients

L
Larry Cripe, MD
18 years - 100 years
All genders
This study investigates how patients with CLL/SLL make decisions about their treatment options. CLL stands for chronic lymphocytic leukemia, and SLL stands for small lymphocytic lymphoma, both of which are types of blood cancers. The study aims to understand patient perspectives on choosing between different treatments and to gather feedback …
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Investigating a Treatment for Kidney Cancer with Immunotherapy

J
Jennifer King
18 years - 100 years
All genders
Phase 2
This study investigates the use of an investigational medication in combination with immunotherapy for patients with renal cell carcinoma (RCC) who have not responded to standard treatment. RCC is a type of kidney cancer that starts in the cells lining the small tubes within the kidney. The purpose of this …
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Study of Investigational Medication for Older Adults with Specific Type of Blood Cancer

R
Rita Assi
18 years - 100 years
All genders
Phase 2
This study investigates treatments for older adults with a type of blood cancer called acute myeloid leukemia (AML) that has a specific mutation known as FLT3. The purpose is to compare different treatments to see which is more effective. AML is a cancer of the blood and bone marrow, where …
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