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Found 163 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

S
Scott Coven
39 years or below
All genders
What is the purpose of this study?To longitudinally assess cognitive outcomes using an a neurocognitive screening battery in children and young adults diagnosed with a CNS tumor. To longitudinally assess the impact of specific therapies on the QOL in children and young adults diagnosed with a CNS tumor.To longitudinally assess …
S
Susan Ballinger
18 years - 100 years
All genders
Phase 3
This study investigates the effects of an investigational medication on appetite loss in patients with advanced cancer. Advanced cancer means the cancer has spread to other parts of the body. The purpose of this study is to compare the investigational medication with another usual medication to see which one is …
M
Mateusz Opyrchal, MD, PhD
18 years - 100 years
All genders
Phase 1/2
What is the purpose of this study?Phase 1a Dose Escalation/Cohort Expansion BBO-10203 Monotherapy Primary: To evaluate the safety and tolerability of BBO-10203, an inhibitor of the PI3Kα:RAS interaction, in subjects with locally advanced unresectable or metastatic (ie, advanced) HER2-positive BC; HR-positive, HER2-negative BC; KRAS mutant NSCLC; and KRAS mutant CRC. Secondary: To evaluate …
J
Jonathan L. Berkowitz, MD, PhD
18 years - 120 years
All genders
Phase 2
This study investigates an investigational medication for treating certain tumors that express a protein called HER2. HER2 is a protein that can affect the growth of some cancer cells. The study includes different types of cancers such as bladder, biliary tract, cervical, endometrial, ovarian, pancreatic, and some rare tumors.Participants will …
R
Rohan Maniar
18 years - 100 years
All genders
Phase 1/2
This study investigates the use of an investigational medication in adults with advanced solid tumors or non-Hodgkin lymphoma (NHL). The purpose is to learn about the safety and effects of different doses and ways of giving the medication. Solid tumors are abnormal masses of tissue that can be cancerous, and …
N
Nabil Adra, MD
15 years - 100 years
All genders
Phase 1
This study investigates the safety and tolerability of an investigational medication in people with advanced solid tumors. Advanced solid tumors are cancers that have spread and are difficult to treat. The purpose of this study is to find out if the investigational medication is safe and to determine the best …
A
Alexia Torke
18 years - 100 years
All genders
This study investigates the impact of informational support versus spiritual care on patients with cancer. Cancer patients often face challenges in coping with their condition and making treatment decisions. Religion and spirituality can play significant roles in their experience. Therefore, this study will evaluate a spiritual care intervention delivered by …
G
Greg Durm, MD
18 years - 100 years
All genders
Phase 1/2
This study investigates an investigational medication for people with solid tumors that have specific KRAS mutations. These mutations are changes in a gene that can affect how cells grow. The purpose of this study is to understand if the investigational medication is safe and can be tolerated by patients with …
M
Marissa Just
30 years or below
All genders
Phase 3
This study investigates treatment strategies for children with favorable histology Wilms tumors (FHWT), which is a common type of kidney cancer in children. The study aims to use risk factors, such as tumor histology, biology, and response to therapy, to determine the most effective treatment plan. Wilms Tumor is a …
J
James Croop, MD, PhD
1 years - 21 years
All genders
This study is designed to investigate whether the use of copanlisib is safe, feasible and beneficial to pediatric patients with solid solid tumors or lymphoma that are recurrent or refractory to standard therapy.
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