A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates treatment options for juvenile myelomonocytic leukemia (JMML), a rare type of blood cancer that affects young children. JMML is a condition where the bone marrow makes too many white blood cells, which can lead to various health problems. The purpose of this study is to test the …
In this prospective and longitudinal natural history study, the aim is to identify variables that affect long-term outcomes following potentially life-saving Definitive Therapy (DT), which includes either 1) allogeneic hematopoietic cell transplant (HCT), or 2) autologous gene therapy (GT).
What is this study about?This phase II/III trial examines whether patients who have undergone surgical removal of bladder, but require an additional treatment called immunotherapy to help prevent their bladder cancer from coming back, can be identified by a blood test. Many types of tumors tend to lose cells or …
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy …
What is the purpose of this study?This trial studies how well 68-Ga RM2 works with PET/MRI in imaging patients with estrogen receptor-positive breast cancer. 68-Ga-RM2 is an agent used in diagnostic imaging.Primary: To describe the safety of 68Ga-R10602.Secondary - To describe the biodistribution of 68Ga-R10602 in Study Participants with hormone …
What is this study about?The National Liver Cancer Screening Trial is an adaptive randomized phase IV Trial comparing ultrasound-based versus biomarker-based screening in 5500 patients with cirrhosis from any etiology or patients with chronic hepatitis B infection. Eligible patients will be randomized in a 1:1 fashion to Arm A using …
This study investigates the safety of using chemoradiation instead of surgery for early stage vulvar cancer. Vulvar cancer is a type of cancer that affects the external female genitalia. In some cases, cancer spreads to nearby lymph nodes. This study looks at patients with a macrometastasis, which means the cancer …
This study investigates the safety and best dose of an investigational medication combined with chemotherapy drugs, fludarabine and cytarabine, for treating certain blood cancers. The cancers include acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and juvenile myelomonocytic leukemia (JMML) that have not responded to previous treatment or have returned after …
WHAT IS CANCER?WHAT IS MULTIPLE MYELOMA?WHAT IS THE STUDY ABOUT?What is cancer?Each cell in your body holds a copy of your DNA. This DNA tells your cells how to do their jobs, like when to copy themselves and when to delete. Your cells copy and delete all the time. This …
This study investigates the effect of adding radiation therapy to usual care for patients with high-risk asymptomatic bone metastases. Bone metastases are cancer cells that have spread to the bones. High-risk means they are more likely to cause problems like fractures or pain. Radiation therapy uses powerful x-rays to kill …