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Found 168 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Low-Dose Investigational Medication for Early-Stage Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 3
This study investigates the use of low-dose tamoxifen compared to usual hormonal therapy in treating post-menopausal women with hormone-positive, HER2 negative early-stage breast cancer. Hormone-positive breast cancer is a type of cancer that grows in response to hormones like estrogen. HER2 negative means the cancer does not have higher levels …
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Study of Eye Health in Patients Using a Medication Being Studied for Cervical Cancer

S
Sharon E. Robertson
18 years - 100 years
Female
Phase 4
This study investigates the effects of an investigational medication on eye health in patients with recurrent or metastatic cervical cancer. Cervical cancer occurs when cells in the cervix grow uncontrollably. This study focuses on understanding any side effects related to the eyes that may arise from the treatment. A side …
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Study of Investigational Imaging and Treatment in Advanced Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 1
This study investigates advanced breast cancer treatment using investigational imaging and therapeutic agents. The purpose of this study is to evaluate the safety and effectiveness of these agents in patients with hormone receptor positive and HER2 negative breast cancer. The imaging agent, designed to detect cancer lesions, will be used …
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Understanding Money Issues for Breast Cancer Patients in Clinical Trials

K
Kathy Miller, MD
18 years - 100 years
All genders
This study investigates the financial barriers faced by breast cancer patients who participate in clinical trials. Breast cancer is a disease where cells in the breast grow uncontrollably. This study looks at costs like lost income, travel, and parking for patients enrolled in these trials.Participants will complete a one-time paper …
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Detecting Prostate Cancer Return with Imaging

C
Clinton Bahler, MD
18 years - 100 years
Male
Phase 3
This study investigates how well a special scan can find prostate cancer that has come back after treatment. Prostate cancer is a disease where cells in the prostate grow out of control. The study uses a technique called PET/CT, which stands for Positron Emission Tomography and Computed Tomography. This scan …
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Investigation of HER2-Targeted Therapy Duration for Early-Stage HER2+ Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 3
This study investigates the effects of different durations of HER2-targeted therapy in patients with early-stage HER2-positive breast cancer. HER2-positive breast cancer is a type of cancer where a protein called HER2 is found on the surface of the cancer cells. This protein can make cancer cells grow faster. The purpose …
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Study on Fertility Decisions for Teens with Cancer

A
Amanda J. Saraf, DO
13 years - 21 years
Male
This study investigates the use of a tool called the Family-Centered Adolescent Sperm Banking Decision Tool (FAST) during fertility consultations. The purpose is to understand the thoughts and experiences of adolescents and their caregivers who have completed or partially completed the FAST. This tool is part of the fertility consult …
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Study on Treatment After Initial Therapy for Residual Triple Negative Breast Cancer

B
Bryan Schneider, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates treatments for patients with residual triple negative breast cancer, a type of breast cancer that does not have estrogen, progesterone, or HER2 receptors. The study uses circulating tumor DNA (ctDNA) to assign participants to different treatment arms based on their genomic markers. Participants with ctDNA positivity and …
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Investigational Treatment Study for Platinum-Resistant Ovarian Cancer

L
Lisa Landrum, MD, PhD, MS
18 years or above
Female
Phase 3
Interventional
This study investigates treatments for women with platinum-resistant epithelial ovarian cancer, which is a type of cancer that does not respond to platinum-based chemotherapy. The purpose is to compare the effects of different treatments, including an investigational medication called nemvaleukin, either alone or in combination with another treatment, pembrolizumab, against …
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Study on Preparation Therapy for Women Undergoing Pelvic Radiotherapy

N
Namita Agrawal
18 years or above
Female
Interventional
This study investigates the feasibility of adding pre-rehabilitation pelvic health physical therapy to the standard radiation treatment plan for women with certain types of cancer. These include cervical, vaginal, vulvar, uterine, or anal cancer. Participants will receive education on using a vaginal dilator during their treatment. The study will also …
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