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Found 152 Neoplasm trials
A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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April Rahrig, MD
This study investigates the use of an investigational medication to prevent cytomegalovirus (CMV) infection in children and adolescents who have undergone a stem cell transplant. Cytomegalovirus is a virus that can cause infections, especially in people with weakened immune systems. "Prophylaxis" means taking a drug to prevent a disease or …
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Mateusz Opyrchal, MD, PhD
What is the purpose of this study?Phase 1a Dose Escalation/Cohort Expansion BBO-10203 Monotherapy Primary: To evaluate the safety and tolerability of BBO-10203, an inhibitor of the PI3Kα:RAS interaction, in subjects with locally advanced unresectable or metastatic (ie, advanced) HER2-positive BC; HR-positive, HER2-negative BC; KRAS mutant NSCLC; and KRAS mutant CRC. Secondary: To evaluate …
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Sandeep Batra, MD
This study investigates a home-based physical activity program designed for Hispanic or Latino/Latina adolescent and young adult (AYA) childhood cancer survivors. After cancer treatment, some AYA survivors may experience long-term effects like weight gain, tiredness, and reduced fitness. Hispanic or Latino/Latina survivors might face a higher risk of these effects. …
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Scott Coven
What is the purpose of this study?To longitudinally assess cognitive outcomes using an a neurocognitive screening battery in children and young adults diagnosed with a CNS tumor. To longitudinally assess the impact of specific therapies on the QOL in children and young adults diagnosed with a CNS tumor.To longitudinally assess …
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Sandeep Batra, MD
What is the purpose of this study?This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent …
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Courtney Rowan, MD
What is the purpose of this study?The goal of this study is to identify and validate response to therapy biomarkers for NIV respiratory support in children with ICCs. The central hypothesis is that response-to-therapy biomarkers can identify those most likely to benefit from intervention with NIV. The rationale is that …
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Sandeep Batra, MD
This study investigates treatments for people with germ cell tumors, which are a type of cancer that starts in the cells that form sperm or eggs. The purpose of this study is to see how well active surveillance works for low-risk germ cell tumors and to compare two chemotherapy treatments, …
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Cindy Yuan
This study investigates the use of an investigational imaging substance in people with advanced solid tumors. The purpose is to understand how safe this substance is and how well it works in taking pictures of tumors inside the body. It will compare these pictures to the ones taken with regular …
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Timothy Masterson
This study investigates two different surgical techniques for treating testis cancer, focusing on retroperitoneal lymph node dissection (RPLND). The study compares the transperitoneal (TP) and extraperitoneal (EP) approaches. RPLND is a surgery to remove lymph nodes from the back of the abdomen. The purpose is to see if the EP …
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Scott Coven
This study investigates treatments for children with Embryonal Tumor with Multilayered Rosettes (ETMR). ETMR is a rare type of brain tumor that occurs in young children. The purpose of the study is to understand how different treatments work for children who have been newly diagnosed with ETMR. Participants in this …
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