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Found 85 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase III Randomized Trial Investigating Bortezomib (NSC# 681239) on a Modified Augmented BFM (ABFM) Backbone in Newly Diagnosed T- Lymphoblastic Leukemia (T-ALL) and T- Lymphoblastic Lymphoma (T-LLy)

S
Sandeep Batra, MD
2-30 years
All genders
This randomized phase III clinical trial compares how well combination chemotherapy works when given with or without bortezomib in treating patients with newly diagnosed T-cell acute lymphoblastic leukemia or stage II-IV T-cell lymphoblastic lymphoma.
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A Pilot Study to assess Theragnostically Planned Liver Radiation with Functional DVH Analysis to Optimize Individualized Radiation Therapy

R
Ryan Rhome, MD
18-100 years
All genders
The purpose of this study is to compare radiation treatment plans that are designed for patients with liver cancer.
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Study of Oral MRT-2359 in Selected Cancer Patients

M
Mateusz Opyrchal, MD, PhD
18 years and older
All genders
Phase 1/2
Interventional
This Phase 1/2, open-label, multicenter study is conducted in patients with previouslyd selected solid tumors, including non-small cell lung cancer (NSCLC), small cell lung(SCLC), high-grade neuroendocrine cancer of any primary site, diffuse large B-cellymphoma (DLBCL), and tumors with L-MYC or N-MYC amplification. Patients receive escalating doses of a GSPT1 molecular …
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A Study to Assess the Effect of Y-90 Therapy on Non-target/Background Liver

M
Mark Tann, MD
18-100 years
All genders
The primary question of interest is quantifying the relationship between Y-90 liver therapy and liver damage.
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A Phase II Pilot Trial to Estimate Survival After a Non-total Body Irradiation (TBI) Based Conditioning Regimen in Patients Diagnosed With B-acute Lymphoblastic Leukemia (ALL) Who Are Pre-allogeneic Hematopoietic Cell Transplantation (HCT) Next-generation-sequence (NGS) Minimal Residual Disease (MRD) Negative

J
Jodi Skiles
1-25 years
All genders
This study will evaluate the use of non- TBI (total body irradiation) conditioning for B-ALL patients with low risk of relapse as defined by absence of NGS-MRD (next generation sequencing minimal residual disease) before receiving a hematopoietic cell transplant (HCT).
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