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Found 148 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

R
Rohan Maniar
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
B
Brian Weiss
12 months - 22 years
All genders
Phase 1
This study investigates the safety and effects of an investigational medication when combined with radiation therapy in children with high grade glioma. High grade glioma is a type of cancer that occurs in the brain. The investigational medication works by blocking signals that make cancer cells grow, which may help …
S
Sherif Farag, MD
All genders
Observational
This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and otherdications.
V
Varun Mittal
18 years - 100 years
All genders
Phase 3
This study investigates the effectiveness of two different treatment regimens for patients undergoing allogeneic peripheral blood stem cell transplantation. The purpose is to compare the outcomes of using Tacrolimus/Methotrexate/Ruxolitinib versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in patients who receive non-myeloablative or reduced intensity conditioning. This type of transplantation involves using donor stem …
S
Sandeep Batra, MD
2 years - 21 years
All genders
Phase 3
Interventional
This study investigates treatment options for children and young adults with low-grade glioma (LGG), a type of brain tumor. The purpose of this study is to compare the effects of an investigational medication with standard chemotherapy treatments, carboplatin and vincristine, in patients who do not have a specific genetic mutation …
M
Mateusz Opyrchal, MD, PhD
18 years - 100 years
All genders
Phase 1
What is the study purpose?KB707-01 is a Phase 1, open-label, multicenter, dose escalation and expansion study to evaluate the safety and tolerability of KB707 in adults with locally advanced or metastatic solid tumors who have progressed on standard of care therapy, cannot tolerate standard of care therapy, refused standard of …
S
Sandeep Batra, MD
3 years - 30 years
All genders
Phase 2
What is the purpose of this study?This phase II trial studies how well lower dose radiotherapy after chemotherapy works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class …
S
Samantha Armstrong
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started to other places in the …
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