Search
Filters
Clear All
  • 1
  • 1
  • 64

Phase

  • 2
  • 5
  • 6
  • 4
  • 45
  • 62
  • 30

Found 66 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase I/II, First-in-Human (FIH), Open-Label, Multiple Centre Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of LM-24C5 in Patients with Advanced Solid Tumors

M
Mateusz Opyrchal, MD, PhD
18 - 100
All genders
Phase 1/2
What is the purpose of this study?To assess the safety and tolerability, obtain the recommended phase 2 dose (RP2D)/optimal biologic dose (OBD) and/or Maximum Tolerated Dose (MTD) for LM-24C5 in subjects with advanced solid tumors.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not …
Learn More

Key Adverse Events Following Childhood Cancer

S
Sandeep Batra, MD
21 or below
All genders
What is the purpose of this study?This clinical trial studies cancer survivors to identify those who are at increased risk of developing late-occurring complications after undergoing treatment for childhood cancer. A patient's genes may affect the risk of developing complications, such as congestive heart failure, avascular necrosis, stroke, and second …
Learn More

AGCT1531: A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors

S
Sandeep Batra, MD
49 or below
All genders
Phase 3
What is the purpose of this study?This phase III trial studies how well active surveillance, bleomycin, carboplatin, etoposide, or cisplatin work in treating pediatric and adult patients with germ cell tumors. Active surveillance may help doctors to monitor subjects with low risk germ cell tumors after their tumor is removed. …
Learn More

Circulating Tumor Cells (CTC) in Lung Cancer

J
Jessica MacLean
S
Shadia Jalal, MD
100 or below
All genders
What is the purpose of the study?The purpose of this study is to examine rare cells called circulating tumor cells that are present in a person's blood when they have lung cancer to see if there is a relationship between a person's cancer symptoms and the number and characteristics of …
Learn More

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

M
Mitesh Shah, MD
100 or below
All genders
Observational
What is the purpose of this study?The objectives of this registry study are to evaluate real-world clinical outcomes andd outcomes that measure the effectiveness and safety of STaRT.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their …
Learn More

The Project: Every Child Protocol: A Registry Eligibility Screening Biology and Outcome Study

S
Sandeep Batra, MD
1 - 25
All genders
What is the purpose of this study?This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent …
Learn More

Tissue Procurement Protocol for the Developmental Therapeutics Clinic National Cancer Institute (NCI)

A
Anna Maria Storniolo, MD
110 or below
All genders
What is the purpose of this study?Adult patients (18 years of age and older) and pediatric patients (younger than 18 years of age) who are being evaluated for and/or treated for cancer at the NIH Clinical Center and at participating sites will be entered onto this tissue procurement protocol for …
Learn More

A Randomized Web-based Physical Activity Intervention among Children and Adolescents with Acute Lymphoblastic Leukemia

S
Sandeep Batra, MD
8 - 15
All genders
What is the purpose of this study?This randomized clinical trial studies how well web-based physical activity intervention works in improving long term health in children and adolescents with newly diagnosed acute lymphoblastic leukemia that shows a decrease in or disappearance of signs and symptoms. Regular physical activity after receiving treatment …
Learn More

NEWLY DIAGNOSED CHILDREN (LESS THAN 10 YEARS OLD) WITH MEDULLOBLASTOMA AND OTHER CENTRAL NERVOUS SYSTEM EMBRYONAL TUMORS: CLINICAL AND MOLECULAR RISK-TAILORED INTENSIVE AND COMPRESSED INDUCTION CHEMOTHERAPY FOLLOWED BY CONSOLIDATION WITH EITHER SINGLE CYCLE (LOW RISK PATIENTS) OR RANDOMIZATION (HIGH RISK PATIENTS) TO either SINGLE-CYCLE or TO THREE TANDEM CYCLES OF MARROW-ABLATIVE CHEMOTHERAPY WITH AUTOLOGOUS HEMATOPOIETIC PROGENITOR CELL RESCUE

S
Scott Coven
10 or below
All genders
What is the purpose of this study?This research study would like to learn more information about patients who have been diagnosed with medulloblastoma and other CNS embryonal tumors. This research study will compare two different treatment regimens to see which is better for treating your child’s type of brain cancer.Goals·        …
Learn More

Pilot Pharmacokinetic Study of VAL-413 (Orotecan) in Patients with Recurrent Pediatric Solid Tumors

K
Kyle William Jackson
1 - 30
All genders
Phase 2
What is the purpose of this study?To establish the recommended phase II dose of a flavored preparation of orally administered irinotecan (VAL-413) when given in combination with temozolomide for five consecutive days. To characterize and compare the pharmacokinetic profiles of VAL-413 and conventional irinotecan given orally To evaluate the palatability …
Learn More
11 - 20 of 66