Found 29 results for Liver Disease/Disorder
A listing of Liver Disease/Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Liver Research Study for Heavy Drinkers
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Raj Vuppalanchi, MD
Do you have liver damage because of excessive alcohol use? Join our study!Researchers at the Indiana University School of Medicine are looking for adult volunteers to take part in a study looking at the link between heavy drinking and liver disease.Your participation may help researchers to gain knowledge that may …
Measuring Patient Reported Needs in Outpatient Liver Disease Management
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Archita Desai, MD
What is the purpose of this study?Patients with chronic liver disease (CLD) are biopsychosocially complex and represent a vulnerable population at high risk for poor health-related outcomes. Beyond their primary liver disease, individuals with CLD often have unmet social needs which serve as important social determinants of health (SODH). For …
A phase 1, open-label, single arm study to evaluate pharmacokinetics, safety, and tolerability of Saroglitazar Magnesium dosed on alternate days in subjects having moderate hepatic impairment with cirrhosis due to cholestatic liver disease
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Raj Vuppalanchi, MD
To evaluate PK after Saroglitazar Magnesium 1 mg dose on alternate days in subjects with moderate hepatic impairment with cirrhosis due to CLD based on Child-Pugh-Turcotte (CPT) score.To assess safety and tolerability of Sa-roglitazar Magnesium 1 mg dose on alter-nate days in subjects with moderate hepatic impairment with cirrhosis due …
Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) (LOGIC)
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Jean Molleston, MD
Cholestasis is a condition in which bile is not properly transported from the liver to the. Cholestasis can be caused by an array of childhood diseases, including the genetic diseases Alagille syndrome (ALGS), alpha-1 antitrypsin (a-1AT) deficiency, bile acidynthesis and metabolism defects, and progressive familial intrahepatic cholestasis (PFIC) or benign …
Functional Assessment in Liver Transplantation (FrAILT) Study; Functional Assessment in Liver Transplant Candidates (FrAILT) Study
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Marwan Ghabril
This will be a prospective cohort study of patients with liver disease. Subjects will undergo geriatric assessments of frailty, functional status, and disability using functional status measures at baseline and at every clinic visit in the pre-transplant setting. Subjects will also answer questions regarding quality of life, personality, and/or cognitive …
The Hospital @ Home Model of Care: A Novel Healthcare Solution for the Management of Decompensated Cirrhosis
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Miranda Stovall
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Archita Desai, MD
What is the purpose of this study?The purpose of this study is to work with patients diagnosed with end-stage liver disease to understand their perspectives on the Health at Home (H@H) Program, including desired outcomes and expectations, perceived barriers and drivers. H@H is an emerging model of home-based care, designed …
Characterization of Patients Referred to Indiana University for Evaluation and Management of Suspected Nonalcoholic Fatty Liver Disease
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Niharika Samala, MD
What is this study about?Patients with nonalcoholic fatty liver disease have varied etiologies, associated risk factors and disease severity. One purpose of this study is to determine the possible etiological factors, risk factors, and disease severity of all patients referred to Digestive and Liver Diseases Clinics for presumed NAFLD. Another …
Utilization of FibroScan in Fontan Associated Liver Disease prior to and after heart transplant or placement of single ventricle ventricular assist device
What is the purpose of this study?In this study, we propose to assess: 1) the role of FibroScan in patients with FALD prior to and after heart transplant or placement of single ventricle ventricular assist device (SVAD); 2) the association between liver stiffness measurement (LSM) from FibroScan and cardiac events, …
Integrated Therapies for Alcohol Use in Alcohol-Associated Liver Disease
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Raj Vuppalanchi, MD
To determine whether interventions directed to treat AUD integrated with sAH therapies will improve a composite endpoint of alcohol and liver-related events at 6 months compared to usual care for AUD (primary endpoint)To compare 90-day survival in patients receiving F-652 with those receiving up to 28 days of prednisone using …
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 3-Arm Study to Investigate the Safety and Efficacy of Efimosfermin Alfa in Participants With Biopsy-Confirmed F2- or F3-Stage Metabolic Dysfunction-Associated Steatohepatitis (Mash) (Zenith-1)
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Raj Vuppalanchi, MD
The purpose of this study is to assess the safety and efficacy of efimosfermin alfa in the resolution of steatohepatitis and improvement of liver-related clinical outcome compared to placebo in individuals with MASH and biopsy-confirmed F2- or F3-stage fibrosis.THIS STUDY IS ENROLLING BY INVITATION ONLY
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