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Found 30 Liver Disease trials

A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Geometric Engineering of Liver Organoid Culture in Pediatric Liver Diseases

C
Chao Jarasvaraparn
17 years or below
All genders
Observational
What is the purpose of this study?Chronic liver disease (CLD) in children can be caused by a variety of conditions and have serious consequences if left untreated. Liver organoids are defined as 3D structure derived from human liver tissue and is a promising new approach to treating liver disease in …
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Role of neutrophil-specific NOX2 in alcohol-induced liver injury

S
Suthat Liangpunsakul, MD
18 years - 70 years
Accepts healthy volunteer
All genders
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …
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Collection of Liver Tissue and a Blood Sample for Future Research

N
Naga Chalasani, MD
18 years or above
All genders
What is the purpose of this study?The aim of this study is to collect a small sample of liver tissue and approximately 15mL of blood from patients who are undergoing elective liver biopsies for clinical purposes to establish and grow a liver tissue bank.  The samples will be used for …
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Liver Fibrosis Study Using Sound Waves

R
Raj Vuppalanchi, MD
18 years or above
All genders
Observational
This study investigates liver fibrosis in patients with known or suspected liver disease. Liver fibrosis is a condition where the liver becomes scarred due to long-term damage. The purpose of this study is to collect data using transient elastography, a method that uses sound waves to measure liver stiffness, which …
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A 5-Year Longitudinal Observational Study of Patients with Nonalcoholic Fatty Liver or Nonalcoholic Steatohepitiis

Niharika Samala, MD
100 years or below
All genders
The purpose of this study is to create a research registry of patients with NAFL (non alcoholic fatty liver) or NASH (non alcoholic steatohepatitis)in order to assess the safety and effectiveness of current and future therapies. The goal is to identify the factors associated with favorable versus suboptimal clinical response …
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TReatment for ImmUne Mediated PathopHysiology (TRIUMPH)

J
Jean Molleston, MD
1 year - 18 years
All genders
Phase 2
Interventional
TReatment for ImmUne Mediated PathopHysiology (TRIUMPH) is a multi-center, three arm,domized, controlled trial of immunosuppressive therapy for children with acute liverure. The study will determine if suppressing inflammatory responses with eitherds or equine anti-thymocyte globulin therapy improves survival for children withhis rare, life-threatening condition.
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Dissecting the Genetic and Environmental Contributions of Autoimmune Liver Disease: Genetic Repository of Autoimmune Liver Disease and Contributing Exposures (GRACE)Study

C
Craig Lammert, MD
7 years or above
All genders
What is the purpose of this study?The overall objective of this proposal is to conduct a systematic approach to dissect both genetic underpinnings and non-genetic factors in the development of adult autoimmune liver diseases including autoimmune hepatitis (AIH), overlap AIH with Primary Biliary Cirrhosis (AIH-PBC), overlap AIH with Primary Sclerosing …
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Post-Traumatic Stress, Depression, and Anxiety Following Liver Transplantation

A
Archita Desai, MD
18 years - 100 years
All genders
Observational
The purpose of this study is to help understand the rates of psychosocial illness in liver transplant recipients and examine their health related quality of life (HR QOL) measures.
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Transient Elastography (TE) for evaluation of liver disease in pediatric patients with intestinal failure

K
Kanika Puri
18 years or below
All genders
We are investigating the use of a painless ultrasound technology called Transient Elastography (TE) to measure changes in the liver that indicate the amount of scar tissue in the liver. Ultrasound technology works by placing a probe on the outside of your body, which uses sound waves to create a …
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Characteristics and Outcomes of Fontan Associated Liver Disease in Children

C
Chao Jarasvaraparn
10 years - 20 years
All genders
Observational
What is this study about?The proposed project is a non-funded, multi-center study designed to evaluate the characteristics and outcomes of Fontan Associated Liver Disease in Children. We will start collecting data prospectively and retrospectively since January 2020. THIS STUDY IS ENROLLING BY INVITATION ONLY -  Potential participants who had a Fontan …
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