Found 29 results for Liver Disease/Disorder
A listing of Liver Disease/Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Prospective Sample Collection Of Subjects For The Development Of Multiple Immunosuppressant Therapeutic Drug Monitoring Assays
A
Asif Sharfuddin
The primary aim of this study is to collect biological samples that may be used in the development of future multi-drug immunosuppressant therapeutic drug monitoring assays in solid organ transplant recipients.THIS STUDY IS ENROLLING BY INVITATION ONLY - The Investigator will collect samples from up to 3,000 adult subjects who …
Dissecting the Genetic and Environmental Contributions of Autoimmune Liver Disease: Genetic Repository of Autoimmune Liver Disease and Contributing Exposures (GRACE)Study
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Craig Lammert, MD
What is the purpose of this study?The overall objective of this proposal is to conduct a systematic approach to dissect both genetic underpinnings and non-genetic factors in the development of adult autoimmune liver diseases including autoimmune hepatitis (AIH), overlap AIH with Primary Biliary Cirrhosis (AIH-PBC), overlap AIH with Primary Sclerosing …
A 5-Year Longitudinal Observational Study of Patients with Nonalcoholic Fatty Liver or Nonalcoholic Steatohepitiis
Niharika Samala, MD
The purpose of this study is to create a research registry of patients with NAFL (non alcoholic fatty liver) or NASH (non alcoholic steatohepatitis)in order to assess the safety and effectiveness of current and future therapies. The goal is to identify the factors associated with favorable versus suboptimal clinical response …
Autoimmune Liver Disease Network for Kids (A-LiNK): Using Patient Data to Transform Care and Improve Outcomes for Children, Adolescents, and Young Adults With Autoimmune Liver Disease
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Kyla Tolliver
What is the purpose of this study?The Autoimmune Liver disease Network for Kids (A-LiNK) is a multi-institutional group with the mission to deliver the best care to kids with pediatric autoimmune liver disease (AILD).This study will establish a shared clinical registry and a learning health network for the participating sites …
Transient Elastography (TE) for evaluation of liver disease in pediatric patients with intestinal failure
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Kanika Puri
We are investigating the use of a painless ultrasound technology called Transient Elastography (TE) to measure changes in the liver that indicate the amount of scar tissue in the liver. Ultrasound technology works by placing a probe on the outside of your body, which uses sound waves to create a …
Creation of specimen biorepository and analysis of transcriptome and metabolome as potential mechanism in intestinal failure associated liver disease in neonate
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Katie Huff
We will build a biorepository of blood and urine samples correlated with clinical data in neonates receiving parenteral nutrition in order to study IFALD
Prevalence of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in High-Risk Patients Presenting to Primary Care
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Raj Vuppalanchi, MD
This study will provide the first comprehensive real-world prevalence data on MASLD in a primary care-based high-risk population, using validated non-invasive imaging. Results will inform evidence-based screening guidelines, support integration of FibroScan into PCP workflows, and facilitate early intervention to reduce progression to advanced liver disease. Identified predictors of significant …
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of Fazirsiran in the Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease With METAVIR Stage F1 Fibrosis
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Raj Vuppalanchi, MD
Why is this study being done?In some people, the liver makes an abnormal version of the alpha-1 antitrypsin (AAT) protein, called Z-AAT. Making an abnormal version of the AAT protein can result in liver disease as Z-AAT builds up in liver cells, which leads to liver problems such as liver …
Characteristics and Outcomes of Fontan Associated Liver Disease in Children
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Chao Jarasvaraparn
What is this study about?The proposed project is a non-funded, multi-center study designed to evaluate the characteristics and outcomes of Fontan Associated Liver Disease in Children. We will start collecting data prospectively and retrospectively since January 2020. THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential participants who had a Fontan …
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