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Found 23 Liver Disease trials

A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Functional Assessment in Liver Transplant Candidates (FrAILT) Study

M
Marwan Ghabril
18 years - 100 years
All genders
Interventional
What is this study about?This will be a prospective cohort study of patients with liver disease. The researchers want to gather information through a series of various tests that can be used in the future to guide diagnosis and treatment of cognitive impairment including Alzheimer’s and related dementias in individuals …
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The Hospital @ Home Model of Care: A Novel Healthcare Solution for the Management of Decompensated Cirrhosis

M
Miranda Stovall
A
Archita Desai, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to work with patients diagnosed with end-stage liver disease to understand their perspectives on the Health at Home (H@H) Program, including desired outcomes and expectations, perceived barriers and drivers.  H@H is an emerging model of home-based care, designed …
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Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) (LOGIC)

J
Jean Molleston, MD
25 years or below
All genders
Observational
Cholestasis is a condition in which bile is not properly transported from the liver to the. Cholestasis can be caused by an array of childhood diseases, including the genetic diseases Alagille syndrome (ALGS), alpha-1 antitrypsin (a-1AT) deficiency, bile acidynthesis and metabolism defects, and progressive familial intrahepatic cholestasis (PFIC) or benign …
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Utilization of FibroScan in Fontan Associated Liver Disease prior to and after heart transplant or placement of single ventricle ventricular assist device

17 years or below
All genders
Observational
What is the purpose of this study?In this study, we propose to assess: 1) the role of FibroScan in patients with FALD prior to and after heart transplant or placement of single ventricle ventricular assist device (SVAD); 2) the association between liver stiffness measurement (LSM) from FibroScan and cardiac events, …
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Geometric Engineering of Liver Organoid Culture in Pediatric Liver Diseases

C
Chao Jarasvaraparn
17 years or below
All genders
Observational
What is the purpose of this study?Chronic liver disease (CLD) in children can be caused by a variety of conditions and have serious consequences if left untreated. Liver organoids are defined as 3D structure derived from human liver tissue and is a promising new approach to treating liver disease in …
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Role of neutrophil-specific NOX2 in alcohol-induced liver injury

S
Suthat Liangpunsakul, MD
18 years - 70 years
Accepts healthy volunteer
All genders
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …
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Nonalcoholic Fatty Liver Disease (NAFLD) Pediatric Database 2

J
Jean Molleston, MD
2 years - 17 years
All genders
The purpose of the NAFLD Pediatric Database 2 is to better understand nonalcoholic fatty liver disease (''NAFLD) by following and evaluating children with this condition yearly.
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A 5-Year Longitudinal Observational Study of Patients with Nonalcoholic Fatty Liver or Nonalcoholic Steatohepitiis

Niharika Samala, MD
100 years or below
All genders
The purpose of this study is to create a research registry of patients with NAFL (non alcoholic fatty liver) or NASH (non alcoholic steatohepatitis)in order to assess the safety and effectiveness of current and future therapies. The goal is to identify the factors associated with favorable versus suboptimal clinical response …
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TReatment for ImmUne Mediated PathopHysiology (TRIUMPH)

J
Jean Molleston, MD
1 year - 18 years
All genders
Phase 2
Interventional
TReatment for ImmUne Mediated PathopHysiology (TRIUMPH) is a multi-center, three arm,domized, controlled trial of immunosuppressive therapy for children with acute liverure. The study will determine if suppressing inflammatory responses with eitherds or equine anti-thymocyte globulin therapy improves survival for children withhis rare, life-threatening condition.
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Dissecting the Genetic and Environmental Contributions of Autoimmune Liver Disease: Genetic Repository of Autoimmune Liver Disease and Contributing Exposures (GRACE)Study

C
Craig Lammert, MD
7 years or above
All genders
What is the purpose of this study?The overall objective of this proposal is to conduct a systematic approach to dissect both genetic underpinnings and non-genetic factors in the development of adult autoimmune liver diseases including autoimmune hepatitis (AIH), overlap AIH with Primary Biliary Cirrhosis (AIH-PBC), overlap AIH with Primary Sclerosing …
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