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Found 165 Tumor trials

A listing of Tumor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigational Treatment for Relapsed Metastatic Germ Cell Tumor

J
Jennifer King
18 years - 100 years
All genders
This study investigates the use of an investigational medication in combination with oral etoposide for patients with relapsed metastatic germ cell tumor (GCT). Germ cell tumors are a type of cancer that begins in the cells that give rise to sperm or eggs. This study is designed to find out …
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Investigating Maintenance Treatment or Observation for Germ Cell Tumors

N
Nabil Adra, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates maintenance treatment with oral etoposide or observation in patients with relapsed germ cell tumors (GCT) who have received high-dose chemotherapy and peripheral blood stem cell transplant. Germ cell tumors are a type of cancer that begins in the cells that give rise to sperm or eggs. This …
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Investigating an Investigational Medication for Certain Types of Cancer

B
Brian Weiss
12 months - 21 years
All genders
Phase 1/2
Interventional
This study investigates the use of an investigational medication in patients with relapsed or refractory solid tumors, including central nervous system tumors and lymphoma. The purpose is to find the best dose and understand the side effects and potential benefits. Solid tumors and lymphoma are types of cancer that can …
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Testis Cancer Surgery Study

T
Timothy Masterson
18 years - 100 years
All genders
This study investigates two different surgical techniques for treating testis cancer, focusing on retroperitoneal lymph node dissection (RPLND). The study compares the transperitoneal (TP) and extraperitoneal (EP) approaches. RPLND is a surgery to remove lymph nodes from the back of the abdomen. The purpose is to see if the EP …
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A Study of DSP107 Alone and in Combination With Atezolizumab for Patients With Advanced Solid Tumors

R
Rohan Maniar
18 years or above
All genders
Phase 1/2
Interventional
What is the purpose of this study?Part 1: A first-in-human, open-label, Phase I dose escalation study of DSP107 monotherapy and combination therapy with atezolizumab in patients with advanced solid tumors. Part 2: Preliminary efficacy assessment of DSP107 in combination with atezolizumab in second or third line treatment of non small …
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The Rare Brain Tumour Consortium Registry and Biobank

S
Scott Coven
18 years or below
All genders
What is the purpose of this study?The Biobank being created by this study is located at the Hospital for Sick Children in Toronto, Canada and is a research registry that collects biological samples and medical information from individuals in participating centers around the world. The purpose of this registry is …
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Studying the Effects of an Investigational Medication in Breast Cancer

R
Rina Yadav
18 years or above
Female
Phase 2
This study investigates the effects of an investigational medication on premenopausal women with a specific type of breast cancer called estrogen receptor-positive, HER2-negative breast cancer. The purpose of the study is to understand how the investigational medication affects tumor cell growth compared to other treatments. The study is divided into …
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A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

M
Marissa Just
30 years or below
All genders
Phase 2
Interventional
What is the purpose of this study?This phase II trial studies how well combination chemotherapy works in treating patients withwly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens suchH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, …
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Investigating Treatment for Children with Favorable Histology Wilms Tumors

M
Marissa Just
30 years or below
All genders
Phase 3
This study investigates treatment strategies for children with favorable histology Wilms tumors (FHWT), which is a common type of kidney cancer in children. The study aims to use risk factors, such as tumor histology, biology, and response to therapy, to determine the most effective treatment plan. Wilms Tumor is a …
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Pilot Pharmacokinetic Study of VAL-413 (Orotecan) in Patients with Recurrent Pediatric Solid Tumors

K
Kyle William Jackson
1 years - 30 years
All genders
Phase 2
What is the purpose of this study?To establish the recommended phase II dose of a flavored preparation of orally administered irinotecan (VAL-413) when given in combination with temozolomide for five consecutive days. To characterize and compare the pharmacokinetic profiles of VAL-413 and conventional irinotecan given orally To evaluate the palatability …
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