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Found 164 Tumor trials

A listing of Tumor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Testicular Tissue Cryopreservation for Fertility Preservation

A
Amanda J. Saraf, DO
100 years or below
Male
Observational
What is the purpose of this study?Testicular tissue cryopreservation is an experimental procedure where a young boy's testicular tissue is retrieved and frozen. This technique is reserved for young male patients who are not yet producing mature sperm, with the ultimate goal that their tissue may be used in the …
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Study on Monitoring Symptoms During Cancer Treatment Using Surveys

J
Jordan Holmes
18 years - 100 years
All genders
This study investigates how completing surveys about symptoms and quality of life during radiation treatment affects symptom management. The focus is on patients who speak English or Spanish and are undergoing treatment for certain cancers, like endometrial, cervical, or prostate cancer. The goal is to see if real-time feedback can …
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Investigating the Effectiveness of Immunotherapy in Recurrent Endometrial Cancer

L
Lisa Landrum, MD, PhD, MS
18 years - 100 years
Female
Phase 2
This study investigates the effectiveness of using a combination of investigational medications, nivolumab and ipilimumab, compared to nivolumab alone in treating patients with recurrent endometrial cancer. Endometrial cancer is a type of cancer that begins in the lining of the uterus. This study focuses on a specific type of endometrial …
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Investigating Methods to Increase Genetic Testing for Cancer Risk in Black Families

N
Nawal Kassem
18 years - 100 years
All genders
This study investigates how to increase genetic testing in Black families with hereditary cancer syndromes. Hereditary cancer syndromes are conditions where gene changes increase the risk of cancer in families. The study focuses on Black patients who have been advised to undergo genetic testing. It aims to see if using …
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Investigating Treatment Deintensification for HPV-Positive Oropharyngeal Cancer

M
Michael W. Sim, MD
18 years - 100 years
All genders
This study investigates a new approach for treating HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). The purpose of this study is to see if reducing the intensity of treatment, based on levels of ctHPVDNA (pieces of cancer DNA in blood samples), can be as effective as the standard treatment. OPSCC is …
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Study Comparing Shorter Treatment to Usual for Early-Stage Breast Cancer

K
Kathy Miller, MD
16 years - 100 years
All genders
Phase 3
This study investigates the effects of shorter chemotherapy-immunotherapy without anthracyclines compared to the usual treatment for early-stage triple negative breast cancer. Triple negative breast cancer is a type of breast cancer that does not have estrogen receptors, progesterone receptors, or too much of the protein called HER2. This study will …
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Investigating a Special Type of Immune Cell Therapy for Acute Myeloid Leukemia (AML)

H
Huda Salman
12 years - 100 years
All genders
This study investigates a treatment for patients with a type of cancer called Acute Myeloid Leukemia (AML). AML is a cancer of the blood and bone marrow that affects white blood cells. This study focuses on patients whose AML has come back or has not responded to previous treatments. The …
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Evaluating Different Methods of Circulating Tumor DNA Quantification in Oncology Patients

T
Tim Lautenschlaeger, MD
18 years - 100 years
Accepts healthy volunteer
All genders
What is the purpose of this study?This study aims to invent a test that can see tiny pieces from people with cancer (specifically DNA from a person’s cancer) in blood and urine better than tests that can currently be done. In the future, this test can possibly be used to …
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Rapid Autopsy Protocol for Patients with Small Cell Lung Cancer

S
Shadia Jalal, MD
18 years - 100 years
All genders
What is the purpose of this study?This is pilot study to establish a rapid autopsy program in Small Cell Lung Cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center and outline the components necessary for tumor tissue collection. This proposal is a collaboration between scientists, lung cancer physicians, pathologists, …
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Study on Therapy Reduction in Early-stage Triple-negative Breast Cancer

N
Nawal Kassem
18 years - 100 years
All genders
Phase 3
This study investigates the effects of continuing pembrolizumab treatment versus observation in patients with early-stage triple-negative breast cancer (TNBC) who have achieved a pathologic complete response (pCR) after receiving chemotherapy and pembrolizumab before surgery. Triple-negative breast cancer is a type of cancer that lacks three common receptors known to fuel …
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