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Found 650 IU Health Enterprise System trials
A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Marissa Just
This study investigates the effectiveness of adding an investigational medication to standard chemotherapy and other treatments in children with high-risk neuroblastoma. Neuroblastoma is a type of cancer that usually affects young children and develops from immature nerve cells. The investigational medication is a monoclonal antibody that targets a molecule found …
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Miranda Stovall
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Archita Desai, MD
What is the purpose of this study?The purpose of this study is to work with patients diagnosed with end-stage liver disease to understand their perspectives on the Health at Home (H@H) Program, including desired outcomes and expectations, perceived barriers and drivers. H@H is an emerging model of home-based care, designed …
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Lisa Landrum, MD, PhD, MS
What is the purpose of this study?This is a clinical trial to test letrozole in patients with uterine leiomyosarcoma. The main question is will treatment with letrozole extend progression-free survival in patients. Patients will receive 2/5 mg of letrozole daily. Translational Objectives: 1. To preliminarily assess IHC hormone receptor expression and correlation …
A Study of DSP107 Alone and in Combination With Atezolizumab for Patients With Advanced Solid Tumors
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Rohan Maniar
What is the purpose of this study?Part 1: A first-in-human, open-label, Phase I dose escalation study of DSP107 monotherapy and combination therapy with atezolizumab in patients with advanced solid tumors. Part 2: Preliminary efficacy assessment of DSP107 in combination with atezolizumab in second or third line treatment of non small …
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Bryan Schneider, MD
What is the purpose of this study?This is a non-randomized observational trial designed to collect detailed clinical, social determinant, and genomic data from patients enrolled in molecular oncology tumor boards across four comprehensive cancer centers.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not …
Investigational Treatment for Craniopharyngioma, a Type of Brain Tumor, in Children and Young Adults
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Scott Coven
This study investigates the use of investigational medications for treating craniopharyngioma in children and young adults. Craniopharyngioma is a type of brain tumor that can affect hormone levels and vision. The study will look at how well the treatment works and if it is safe for the participants.Participants will be …
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Mohammad Al-Haddad, MD
What is the purpose of this study?The purpose of this study is to learn the best approach to treating patients with known or suspected Barrett's esophagus by comparing endoscopic surveillance to endoscopic eradication therapy. This is a multicenter study involving several academic, community and private hospitals around the United States. …
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Wayne Gray
This study investigates the effects of an investigational medication on heart failure and kidney function. Heart failure is a condition where the heart cannot pump blood as well as it should. This study compares the investigational medication to another treatment to see how they affect heart failure events and cardiovascular …
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David Haas, MD
What is the purpose of this study?This study is being conducted to evaluate the current state of knowledge regarding long-term child outcomes among children born to women with mild CHTN who received antihypertensive therapy in pregnancy or who had preeclampsia. This study will compare long-term outcomes, including neurodevelopment and growth. …
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Kerry Hege, MD
This study investigates the use of prophylaxis with an investigational medication in children diagnosed with severe von Willebrand disease. Von Willebrand disease is a bleeding disorder caused by low levels or dysfunction of von Willebrand factor, a protein that helps blood clot. This study aims to evaluate the effectiveness of …
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