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Found 645 IU Health Enterprise System trials

A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

PREVENT ALL ALS

C
Cynthia Bodkin, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?PREVENT ALL ALS is a prospective, observational cohort study enrolling individuals at risk for carrying inherited genetic variants known to be causative for ALS. This is a longitudinal observational study involving collection of clinical data, outcomes andbiofluid samples. There is also an optional sub-study …
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Neonatal Caloric Absorption in Relation to Growth Outcomes and Nutrition

K
Katie Huff
34 weeks - 100 years
All genders
Observational
The goal of this study is to learn more about how babies in the NICU are able to take in and use the food they are getting. We want to follow babies during their stay in the NICU and measure their input and output, essentially, what’s in their diet and …
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Investigational Treatment for Relapsed Metastatic Germ Cell Tumor

J
Jennifer King
18 years - 100 years
All genders
This study investigates the use of an investigational medication in combination with oral etoposide for patients with relapsed metastatic germ cell tumor (GCT). Germ cell tumors are a type of cancer that begins in the cells that give rise to sperm or eggs. This study is designed to find out …
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The Return of the Pancreas: Evaluating impact of CFTR modulators on pancreatic function

M
Molly Bozic, MD
18 years or below
All genders
Interventional
What is the purpose of this study?This study aims to see how often children with cystic fibrosis (CF) develop normal pancreatic function after starting treatment with CFTR modulators and to identify what factors might influence this change. We will also look at whether it is safe for these patients to …
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Validating Ten Test efficacy of sensation in patients with traumatic upper extremity injuries

E
Erin Weber
5 years - 100 years
All genders
Interventional
What will happen during the study?This study aims to enhance our understanding of the effectiveness of a noninvasive, simplistic examination for hand sensation to help determine the need for invasive intervention. Hopefully, this will lead to improved quality of care provided for individuals with traumatic nerve injuries to the upper …
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ARTEMIS - Effects of Ziltivekimab Versus Placebo on Cardiovascular Outcomes in Patients With Acute Myocardial Infarction

R
Rolf Kreutz, MD
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes.THIS STUDY IS ENROLLING BY …
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Characterization of the neural correlates of anesthetic-induced intraoperative dream states using stereoelectroencephalography.

D
David Purger
18 years - 100 years
All genders
Observational
What is the purpose of this study?Dreams experienced during emergence from anesthesia have been associated with improvement in trauma-related psychiatric disorders. This study aims to characterize the brain network activity patterns associated with anesthetic-induced intraoperative dreams to gain insight into the underlying mechanisms of the phenomenon and its potential therapeutic …
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Study on Investigational Medication for CIDP

C
Cynthia Bodkin, MD
18 years - 75 years
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication compared to a placebo in adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). CIDP is a condition where the body's immune system attacks the protective covering of the nerves, leading to weakness and numbness. The study aims to understand how well the …
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An Open Label Study to Evaluate the Long-term Safety and Efficacy of Odevixibat (A4250) in Patients With Alagille Syndrome

K
Kyla Tolliver
100 years or below
All genders
Phase 3
Interventional
What is the purpose of this study?The purpose of this study is to assess the long-term safety and effectiveness of odevixibat in participants with Alagille syndrome (ALGS).The participants of this study will have ALGS a rare genetic disorder that can affect multiple organ systems of the body including the liver, …
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Use of Point-of-Care Ultrasound (POCUS) for the Diagnosis of Acute Chest Syndrome in Patients with Sickle Cell Disease

S
Seethal Jacob, MD
25 years or below
All genders
Observational
What is the purpose of this study?Acute chest syndrome (ACS) is a complication of sickle cell disease requiring hospitalization that is characterized by symptoms of fever, low oxygen levels or difficulty breathing in the setting of a new lung finding on chest x-ray. Chest x-rays have historically been used as …
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