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Found 610 IU Health Enterprise System trials
A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Andrew Schwaderer, MD
What is the purpose of this study?The purpose of this study is to develop a test for kidney disease that does not require a kidney biopsy or blood draw. We will look at urine samples under a microscope and see if we find patterns in the kind of cells and …
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James Chmiel
The purpose of this study is to evaluate the pharmacokinetics, safety, tolerability andy of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants with at1 triple combination responsive (TCR) mutation in the cystic fibrosis transmembraneductance regulator (CFTR) gene.
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Erika Daley
This protocol describes a multicenter, prospective randomized superiority trial comparingunctional outcomes between children treated with sedated reduction versus no formalduction.
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Kate Hawa
This study will evaluate changes in the fecal microbiome in constipated pediatric patients before and after antegrade continence enema placement and initiation of antegrade enemaushes. Subjects will have their microbiome sequenced prior to placement by obtaining a. Pre-antegrade continence enema placement results will be compared to fecalbtained at 0, 4, …
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Marcia Felker, MD
What is the purpose of this study?This is a multicenter, prospective, observational Phase 4 study in the United States. The study is designed to collect both medical history and prospective data on Duchenne muscular dystrophy (DMD) treatment outcomes in participants receiving delandistrogene moxeparvovec as part of clinical care, compared to …
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Steven Rhodes
This study investigates the use of an investigational medication to prevent the growth of plexiform neurofibromas in children with Neurofibromatosis Type 1 (NF1). NF1 is a genetic disorder that often causes tumors to grow on nerve tissues, which can lead to various health problems. The study aims to see if …
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Raj Vuppalanchi, MD
Why is this study being done?In some people, the liver makes an abnormal version of the alpha-1 antitrypsin (AAT) protein, called Z-AAT. Making an abnormal version of the AAT protein can result in liver disease as Z-AAT builds up in liver cells, which leads to liver problems such as liver …
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Attaya Suvannasankha, MD
This study investigates a treatment for multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. The purpose of the study is to see if the investigational treatment can improve cancer outcomes and bone health.Participants will have standard clinical assessments, such as blood draws and bone …
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Courtney Rowan, MD
What is the purpose of this study?The goal of this study is to identify and validate response to therapy biomarkers for NIV respiratory support in children with ICCs. The central hypothesis is that response-to-therapy biomarkers can identify those most likely to benefit from intervention with NIV. The rationale is that …
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Marissa Just
This phase II trial tests how well nivolumab in combination with chemotherapy drugs along with radiation therapy works in treating patients with nasopharyngeal cancer. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to …
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