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Found 645 IU Health Enterprise System trials

A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A type I hybrid effectiveness-implementation study of a parent-centered tool to promote shared decision-making in hypospadias care

M
Martin Kaefer, MD
100 years or below
All genders
Interventional
What is the purpose of this study?Aim 1. Compare the effect of the Hypospadias Hub Intervention vs. control on the quality of SDM. Aim 2. Compare the effect of the Hypospadias Hub Decision Support Intervention vs. control on decisional conflict, decision-relevant knowledge, and decisional regret. Aim 3. Assess barriers and …
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Pediatric IBD Biobank

S
Steven Steiner, MD
100 years or below
All genders
Observational
What is the purpose of this study?The purpose of this study is to provide a framework for collecting biospecimens from pediatric patients with IBD or suspected to have IBD, from which clinical data can be linked to conduct a variety of research studies which may include:Understanding the genetic, environmental, and …
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Stent Omission After Ureteroscopy and Lithotripsy in the Michigan Urological Surgery Improvement Collaborative (SOUL MUSIC)

M
Marcelino Rivera
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This is a multicenter prospective trial with randomized and observational cohorts assessing patient-reported outcomes and unplanned healthcare utilization following ureteroscopic treatment of renal and ureteral stones, with placement versus omission of a ureteral stent.The study team hypothesizes that:Pain interference change from pre-surgery to Day …
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Study on Long-Term Effects of an Investigational Medication for Myotonic Dystrophy Type 1 (DM1)

A
Adam Comer
16 years - 17 years
All genders
Phase 3
Interventional
This study investigates the long-term effects of an investigational medication for Myotonic Dystrophy Type 1 (DM1). DM1 is a genetic disorder that affects muscle function and can cause muscle weakness and stiffness. This study aims to understand how the investigational medication affects people with DM1 over a long period.Participants will …
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Study on Support for Cancer Patients

A
Alexia Torke
18 years - 100 years
All genders
This study investigates the impact of informational support versus spiritual care on patients with cancer. Cancer patients often face challenges in coping with their condition and making treatment decisions. Religion and spirituality can play significant roles in their experience. Therefore, this study will evaluate a spiritual care intervention delivered by …
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Study of Investigational Medication in Combination with Other Treatments for Extensive Stage Small-Cell Lung Cancer

M
Misty D. Shields, MD, PhD
18 years - 100 years
All genders
Phase 3
This study investigates the effects of an investigational medication combined with other treatments for extensive stage small-cell lung cancer (ES-SCLC). ES-SCLC is a type of lung cancer that has spread extensively within the body. The purpose is to see if the investigational medication can improve overall survival when used with …
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Study of Treatments for Relapsed B-Cell Acute Lymphoblastic Leukemia

S
Sandeep Batra, MD
1 year - 30 years
All genders
Phase 2
Interventional
This study investigates the effects of two investigational medications, blinatumomab and nivolumab, in patients with B-cell acute lymphoblastic leukemia (B-ALL) that has relapsed. B-ALL is a type of cancer that affects the white blood cells. The study includes patients with Down syndrome and aims to compare the outcomes of using …
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Investigating Treatments for Fatty Liver Disease Related to Metabolic Issues

R
Raj Vuppalanchi, MD
18 years - 100 years
All genders
Interventional
This study investigates metabolic dysfunction-associated steatotic liver disease (MASLD), a condition where fat builds up in the liver due to metabolic issues. The purpose of this study is to assess the safety and effectiveness of different investigational medications for adults with MASLD who are at high risk of serious liver …
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Study on Therapy for Depression in People with HIV

S
Samir Gupta, MD
18 years - 100 years
All genders
Interventional
This study investigates how treating depression in people with HIV might affect insulin resistance, which is when the body doesn't use insulin effectively to control blood sugar. The study focuses on adults with HIV who are already on antiretroviral therapy and are experiencing depression. The purpose is to see if …
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Investigating Fairness in Liver Transplant Referrals

L
Lauren Nephew
18 years - 75 years
All genders
This study investigates how to improve fairness in liver transplant referrals. The purpose is to develop and test a program called LT-CARE, which aims to address barriers faced by patients, healthcare providers, and the health system. The study will be conducted in five community gastroenterology practices that serve groups experiencing …
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