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Found 594 results for iu-health-enterprise-system

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Indiana University Orthopaedic Sports Medicine Cohort Data Repository

B
Bryan Saltzman
18 years - 30 years
All genders
Observational
The purpose of this study is to prospectively collect patient-reported outcome measures, biospecimens, and imaging on patients who undergo orthopaedic sports medicine surgeries. These data will be used to determine predictors and correlates of joint damage (i.e. cartilage, ligament or meniscal damage, as well as osteoarthritis and arthrofibrosis) on the …

Stone and Laser Therapies Post-Market Study SALT Study

M
Marcelino Rivera
18 years - 100 years
All genders
Observational
The purpose of this study is to obtain post-market safety and device performance data for qualified BSC Stone and BPH devices used during a diagnostic and/or therapeutic urinary tract procedure (e.g., transurethral or percutaneous access routes) or benign prostatic hyperplasia (BPH) treatment.THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential …

Studying DNA Damage and Repair in Lung Diseases

C
Catherine Sears, MD
All genders
We will collect cells from the airways and blood of adult patients undergoing clinical bronchoscopy to study how these cells repair DNA after exposure to airborne pollutants like tobacco smoke. We will grow these airway cells in a lab setting to create a 3D model of the lung's surface and …

North American Fetal Therapy Network Fetal Myelomeningocele Repair Registry

H
Hiba Mustafa, MD
18 years - 100 years
Female
The data in the registry will be used to generate retrospective evaluations, investigations, and research studies.Objectives: (primary and important secondary objectives)•    Collect and analyze data regarding maternal outcomes at maternal-fetal surgery and delivery, with the ability to track subsequent reproductive outcomes.•    Collect and analyze data regarding fetal/neonatal outcomes at maternal-fetal surgery, birth …

Duchenne Cardiomyopathy Mitigation Sglt2 Inhibitor (Cherish) Pharmacokinetic Study

L
Larry Markham
8 years - 18 years
All genders
Interventional
This is a pharmacokinetic study (PK Study) to better understand empagliflozin dosing in pediatric Duchenne muscular dystrophy patients. Empagliflozin is currently used off-label in this population due to the mortality benefits seen in adult cardiomyopathy and heart failure. We will perform PK studies in DMD patients of various ages and …

Music and Imagery to Support Self-Care Management in Adolescents and Young Adults with Sickle Cell Disease

S
Sheri Robb
14 years - 22 years
All genders
Interventional
The overall goal of this study is to examine whether an individual Music and Imagery (MI) intervention can produce a clinically meaningful change in pain, depressive symptoms, and anxiety for adolescents and young adults with sickle cell disease.THIS STUDY IS ENROLLING BY INVITATION ONLY - We will recruit AYA from …

Pure: Proteome Analysis of Urgo Clean Ag-Treated Regenerative Wound Exudate

M
Mithun Sinha
18 years - 100 years
All genders
Interventional
Single-site, prospective, observational/specimen-collection pilot embedded in standard-of-care venous leg ulcer (VLU) management. One target dressing will be collected after 7 days of wear for proteomic analysis. THIS STUDY IS ENROLLING BY INVITATION ONLY - This study is enrolling adults (≥18 years) with a chronic VLU receiving standard compression therapy and presenting …

Circulating Extracellular Vesicle Biomarkers of Stroke and Cerebrovascular Disease

C
Candice Brown
All genders
Observational
The purpose of this study is to understand the reasons why people develop strokes and how strokes contribute to the onset of dementia. We will do this by comparing people who have had an ischemic stroke with people who have silent brain infarcts, which are also called silent strokes. Silent …

Collection of Nasal Nitric Oxide in Persons with Suspected Cases of Primary Ciliary Dyskinesia

E
Evans Machogu, MD
All genders
Primary ciliary dyskinesia (PCD) is a genetic condition in which the cilia lining the airway, ears, and sinuses function abnormally. When functionality is abnormal, a buildup of bacteria and debris can accumulate in the lungs, airway, and sinuses, leading to an increased chance of developing infection and bronchiectasis. PCD is …

Enroll-HD: Registry trial for participants with Huntington’s disease

C
Christopher James
Accepts healthy volunteer
All genders
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD …
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