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Found 607 iu-health-enterprise-system trials
A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Jonathan L. Berkowitz, MD, PhD
This study investigates the use of biomarkers to help diagnose and manage patients in a personalized way. Biomarkers are substances in the body that can indicate a disease. This study looks at changes in DNA and RNA, which are molecules that carry genetic information, to find new ways to identify …
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Caroline Rouse, MD
The primary aim of this study is to evaluate patient knowledge regarding cardiovascular risk during pregnancy in people with CHD of reproductive age (16-49 years) following the passing of Indiana Senate Bill-1.Secondary outcomes include evaluation between perceived and actual cardiovascular risk of pregnancy in people with CHD and discrepancy between …
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Michelle C. Starr, MD
Children born prematurely have increased risks of chronic kidney disease (CKD) and end-stage kidney disease compared to children born full-term. The factors which contribute to this risk are unclear, and one potential factor is the impact of food insecurity and maternal malnutrition. The purpose of this project is to describe …
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Jeremy Herrmann, MD
What is the purpose of this study?SANOFI Genzyme collects thymus fragments from pediatric cardiothoracic centers. These thymus fragments are used for the extraction of thymocytes to manufacture the medicine named Thymoglobuline. This medication is used in organ transplantation and in hematological disorders. THIS STUDY IS ENROLLING BY INVITATION ONLY - Subjects …
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Marianne Matthias
What is the purpose of this study?This is phase 2 of a two-phase project with the overarching goal of testing a decision aid paired with coaching sessions, tailored to Black patients with comorbid chronic pain and depression. The decision aid/coaching sessions are designed to help people learn more about other …
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Katelyn Makar
What is the purpose of this study?Craniosynostosis can affect normal brain development by causing local or regional increases in intracranial pressure. The goals of surgery in the treatment of craniosynostosis are to improve the appearance and morphology of the skull and to prevent functional disturbances such as intracranial hypertension and …
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Jennifer Ivanovich
What is the purpose of this study?In partnership with Indiana Biosciences Research Institute, we will develop new models to study pediatric osteosarcoma. We will invite children with Li-Fraumeni syndrome, hereditary retinoblastoma syndrome, or Rothmund-Thompson syndrome to participate. These three syndromes are associated with an increased risk to develop osteosarcoma. THIS STUDY …
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Jignesh Tailor
The purpose of this study is to collect tissue, blood, and cerebrospinal fluid (CSF) in patients with conditions affecting the brain and spinal cord. CSF is a clear fluid found in the brain and spine. This study aims to develop a repository of biospecimens and clinical data for patients who …
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Mateusz Opyrchal, MD, PhD
What is the purpose of this study?Phase 1a Dose Escalation/Cohort Expansion BBO-10203 Monotherapy Primary: To evaluate the safety and tolerability of BBO-10203, an inhibitor of the PI3Kα:RAS interaction, in subjects with locally advanced unresectable or metastatic (ie, advanced) HER2-positive BC; HR-positive, HER2-negative BC; KRAS mutant NSCLC; and KRAS mutant CRC. Secondary: To evaluate …
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Timothy Masterson
This study investigates two different surgical techniques for treating testis cancer, focusing on retroperitoneal lymph node dissection (RPLND). The study compares the transperitoneal (TP) and extraperitoneal (EP) approaches. RPLND is a surgery to remove lymph nodes from the back of the abdomen. The purpose is to see if the EP …
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