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Found 645 iu-health-enterprise-system trials

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Autoimmune Liver Disease Network for Kids (A-LiNK): Using Patient Data to Transform Care and Improve Outcomes for Children, Adolescents, and Young Adults With Autoimmune Liver Disease

K
Kyla Tolliver
1 years - 17 years
All genders
Observational
What is the purpose of this study?The Autoimmune Liver disease Network for Kids (A-LiNK) is a multi-institutional group with the mission to deliver the best care to kids with pediatric autoimmune liver disease (AILD).This study will establish a shared clinical registry and a learning health network for the participating sites …
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The Assessment of Smart Phone Everyday Tasks (ASSET): A new IADL test for early AD

L
Liana Apostolova, MD
55 years - 90 years
Accepts healthy volunteer
All genders
What is the purpose of this study?The overall goal of this project is to validate a novel performance-based IADL instrument that uses a smartphone to assess healthcare-related daily activities, ASSET. This IADL test has been designed to tap the high-level tasks that challenge seniors in daily life, to serve as …
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Investigating Treatment Completion in Breast Cancer Patients

T
Tarah Ballinger, MD
18 years - 100 years
Female
This study investigates how genetic ancestry affects the completion of treatment in patients diagnosed with breast cancer. Breast cancer is a disease where cells in the breast grow out of control. This study involves newly diagnosed women with stages I-III breast cancer who self-report as Black or White.Participants will provide …
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Investigating Methods to Increase Genetic Testing for Cancer Risk in Black Families

N
Nawal Kassem
18 years - 100 years
All genders
This study investigates how to increase genetic testing in Black families with hereditary cancer syndromes. Hereditary cancer syndromes are conditions where gene changes increase the risk of cancer in families. The study focuses on Black patients who have been advised to undergo genetic testing. It aims to see if using …
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Investigating Treatment Deintensification for HPV-Positive Oropharyngeal Cancer

M
Michael W. Sim, MD
18 years - 100 years
All genders
This study investigates a new approach for treating HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). The purpose of this study is to see if reducing the intensity of treatment, based on levels of ctHPVDNA (pieces of cancer DNA in blood samples), can be as effective as the standard treatment. OPSCC is …
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Indiana University Gastric Electrical Stimulation Registry

J
John Wo, MD
18 years - 80 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to develop a clinical registry in patients with Gastric Electrical Stimulation (GES) therapy for gastroparesis to support future gastrointestinal therapies, medical procedures and diagnostics. This clinical registry will support future clinical and translational research. Gastroparesis is an illness …
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Study of Investigational Medication with Chemotherapy for Certain Blood Cancers

B
Brian Weiss
1 year - 18 years
All genders
Phase 1
This study investigates the safety and best dose of an investigational medication combined with chemotherapy drugs, fludarabine and cytarabine, for treating certain blood cancers. The cancers include acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and juvenile myelomonocytic leukemia (JMML) that have not responded to previous treatment or have returned after …
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Determining the presence and significance of atherosclerotic plaque-associated biofilms in peripheral arterial disease

M
Mithun Sinha
18 years - 100 years
All genders
Observational
What is the purpose of this study?This study will examine the relationship between bacteria and biofilms in tibial arteries and lower limb tissue and patient characteristics in a population with critical limb threatening ischemia (CLTI), who have undergone lower extremity amputation. The study will analyze tissue samples from amputation specimens …
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Continuous Glucose Monitoring for Gestational Diabetes: An Ancillary Study to the iGDM Trial

C
Christina M. Scifres, MD
18 years - 100 years
Female
Observational
What is the purpose of this study?The purpose of this ancillary study to the iGDM randomized clinical trail is to determine whether CGM can reveal additional information about maternal glucose values above and beyond the information obtained from checking blood glucose values 4 times per day. THIS STUDY IS ENROLLING BY …
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Study on Therapy Reduction in Early-stage Triple-negative Breast Cancer

N
Nawal Kassem
18 years - 100 years
All genders
Phase 3
This study investigates the effects of continuing pembrolizumab treatment versus observation in patients with early-stage triple-negative breast cancer (TNBC) who have achieved a pathologic complete response (pCR) after receiving chemotherapy and pembrolizumab before surgery. Triple-negative breast cancer is a type of cancer that lacks three common receptors known to fuel …
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