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Found 573 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

MOSES Lithotripsy Technology Applied to Stone Fragmentation during Ureteroscopy.

M
Marcelino Rivera
A
Amy Krambeck, MD
18 years - 100 years
All genders
The purpose of this study is to determine to the effects of MOSES laser modulation technology can improve the safety and efficiency to laser fragmentation resulting in decreased total laser time, reduced potential for injury to the patient, and total operating room time and utilization.
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A Phase 3, Randomized, Open-label, Multicenter Study Comparing Ponatinib Versus Imatinib, Administered in Combination With Reduced-Intensity Chemotherapy, in Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

E
Elizabeth Martin
18 years - 100 years
All genders
The primary objective of the study is to compare the efficacy of ponatinib versus imatinib, administered as first-line therapy in combination with reduced-intensity chemotherapy, in patients with newly diagnosed Ph+ ALL, as measured by the MRD-negative CR rate at the end of induction
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Clinical Evaluation of New Sexually Transmitted Infection/Vaginitis Test

A
Aaron Ermel, MD
18 years - 100 years
Accepts healthy volunteer
All genders
The purpose of this study is to evaluate the performance of a new test that will detect and identify microorganisms responsible for sexually transmitted infections and vaginitis.
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High Intensity Training in Incomplete Spinal Cord Injury

T
T. George Hornby
18 years - 75 years
All genders
The purpose of this study is to investigate the effectiveness of two different walking training procedures on the recovery of mobility, walking and other measures of health in individuals with motor incomplete spinal cord injury.  
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Influence of cooling duration on efficacy in cardiac patients (ICECAP Study)

B
Benton Hunter, MD
18 years - 100 years
All genders
To characterize the duration response curve for hypothermia and determine in each of two populations:A. the shortest duration of cooling that provides the maximal treatment effect, andB. whether the  duration-response implies efficacy versus no cooling This study is enrolling comatose adult survivors of out of hospital cardiac arrest that have …
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Post-approval Study of Transcarotid Artery Revascularization in Standard Risk Patients With Significant Carotid Artery Disease

R
Raghu Motaganahalli, MD
18 years - 79 years
All genders
Observational
The study objective is to evaluate real world usage of the ENROUTE Transcarotid Stent when used with the ENROUTE Transcarotid Neuroprotection System in patients at standard risk fordverse events from carotid endarterectomy
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Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures

K
Karl Shively
B
Brian Mullis, MD
18 years - 80 years
All genders
Phase 3
Interventional
The proposed study is a two arm, pragmatic, randomized controlled multicenter Phase IIIy trial. 1,000 patients with tibia fractures treated with intramedullary (IM)will be randomized into two treatment arms. The control arm will receive standard paingement and no NSAIDs. The treatment arm will receive standard pain management plus up toweeks …
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Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease (DIVERSITYLTE)

M
Matthew Bohm, DO
18 years or above
All genders
Phase 3
Interventional
The primary objective of this study is to observe the long-term safety of filgotinib indults who have completed or met protocol specified efficacy discontinuation criteria in agotinib treatment study in Crohn's disease (CD).
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Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome (LEOPARDS)

C
Courtney Rowan, MD
44 weeks - 17 years
All genders
Observational
The overall goal of the study is to risk stratify pediatric Acute Respiratory Distressyndrome (ARDS) patients and to identify sub-phenotypes with shared biology in order toy target therapies in future trials. This is a prospective, multicenter study of 500 intubated children with ARDS, with planned blood collection within 24 hours …
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NGAL Usage In Determining AKI Risk in Critically Ill Children

C
Christopher Mastropietro, MD
3 months - 22 years
Accepts healthy volunteer
All genders
This is a prospective, observational, non-significant risk clinical study to validate the performance of BioPorto Diagnostics’ The NGAL TestTM in patients aged ≥ 90 days to < 22 years of age that have been admitted to the Pediatric Intensive Care Unit (PICU) with at least one of the following within …
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